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Artikel Jurnal Teks lengkap
Changes in the Expression of Human Cell Division Autoantigen-1 Influence Toxoplasma gondii Growth and Development
Toxoplasma is a significant opportunistic pathogen in AIDS, and bradyzoite differentiation is the critical step in the pathogenesis of chronic infection. Bradyzoite development has an apparent tropism for cells and tissues of the central nervous system, suggesting the need for a specific molecular…
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Artikel Jurnal Teks lengkap
Correction: The Tripartite Associations between Bacteriophage, Wolbachia, and Arthropods
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Artikel Jurnal Teks lengkap
Quantitative Membrane Proteomics Reveals New Cellular Targets of Viral Immune Modulators
Immunomodulators of pathogens frequently affect multiple cellular targets, thus preventing recognition by different immune cells. For instance, the K5 modulator of immune recognition (MIR2) from Kaposi sarcoma–associated herpesvirus prevents activation of cytotoxic T cells, natural killer cells…
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Artikel Jurnal Teks lengkap
SabA Is the H. pylori Hemagglutinin and Is Polymorphic in Binding to Sialylated Glycans
Adherence of Helicobacter pylori to inflamed gastric mucosa is dependent on the sialic acid–binding adhesin (SabA) and cognate sialylated/fucosylated glycans on the host cell surface. By in situ hybridization, H. pylori bacteria were observed in close association with erythrocytes in capillaries…
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Artikel Jurnal Teks lengkap
IAP-IAP Complexes Required for Apoptosis Resistance of C. trachomatis –Infected Cells
Host cells infected with obligate intracellular bacteria Chlamydia trachomatis are profoundly resistant to diverse apoptotic stimuli. The molecular mechanisms underlying the block in apoptotic signaling of infected cells is not well understood. Here we investigated the molecular mechanism by which…
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Artikel Jurnal Teks lengkap
EC 5 S Ubiquitin Complex Is Recruited by KSHV Latent Antigen LANA for Degradation of the VHL and p53 Tumor Suppressors
Cellular protein degradation pathways can be utilized by viruses to establish an environment that favors their propagation. Here we report that the Kaposi's sarcoma–associated herpesvirus (KSHV)-encoded latency-associated nuclear antigen (LANA) directly functions as a component of the EC5S…
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Artikel Jurnal Teks lengkap
Recent Common Ancestry of Ebola Zaire Virus Found in a Bat Reservoir
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Artikel Jurnal Teks lengkap
PLoS Biology Issue Image | Vol. 4(10) October 2006
Rescue of sun sensitivity and premature aging.: Rescue of sun sensitivity and premature aging by embryonic lethal Xpd alleles in compound heterozygote mice suggests new thinking about recessive disorders in humans (see Mitchell et al.). Depicted is an artistic representation of the two alleles…
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Artikel Jurnal Teks lengkap
PLoS Medicine Issue Image | Vol. 3(10) October 2006
Social Medicine across the Ages.: The cover image takes its theme from Dorothy Porter's article, which looks at the historical roots of social medicine and asks where it is heading. The article is part of a special collection of eleven magazine pieces and five original research papers examining…
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Artikel Jurnal Teks lengkap
Complement Factor H Gene Abnormalities in Haemolytic Uraemic Syndrome: From Point Mutations to Hybrid Gene
Noris and Remuzzi discuss a new study showing an association between atypical haemolytic uremic syndrome and a hybrid complement gene,CFH/CFHL1.
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Artikel Jurnal Teks lengkap
Can the Severity of Normal Tissue Damage after Radiation Therapy Be Predicted?
Begg discusses a new study by Svensson and colleagues in which the researchers attempted to elucidate genetic factors involved in late radiation toxicity.
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Artikel Jurnal Teks lengkap
HIV, Stigma, and Rates of Infection: A Rumour without Evidence
Although HIV-related stigma is often seen as the greatest barrier to controlling the HIV epidemic, this assertion is still only a hypothesis, say Reidpath and Chan.
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Artikel Jurnal Teks lengkap
Research Ethics Boards: No Data on Quality of For-Profit or Non-Profit IRBs
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