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Artikel Jurnal Teks lengkap
PLoS Computational Biology Issue Image | Vol. 2(6) June 2006
Min protein locations in simulated filamentous E. coli: Snapshot of Min protein locations in simulated filamentous (ftsZ-), wild-type and spherical (rodA-) Escherichia coli (see Fange and Elf). A stochastic reaction–diffusion model is used to account for the spatiotemporal Min oscillations in…
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Artikel Jurnal Teks lengkap
PLoS Genetics Issue Image | Vol. 2(6) June 2006
The Xenopus tropicalis dwarf mutant yodaa (bottom) and a wild-type sibling: The Xenopus tropicalis dwarf mutant yodaa (bottom) and a wild-type sibling (top) are stained with anti-Laminin 1 antibody to highlight the boundaries between developing muscle blocks. The yodaa locus was identified in a…
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Artikel Jurnal Teks lengkap
PLoS Pathogens Issue Image | Vol. 2(6) June 2006
Schistosome egg excretion: A female schistosome excreting an egg through the gonopore. The female schistosome resides in a ventral groove of the male, the gynecophoric canal. The male worm sends a stimulus to regulate female-specific gene expression that in turn controls female reproductive…
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Artikel Jurnal Teks lengkap
Noise-Induced Min Phenotypes in E. coli
The spatiotemporal oscillations of the Escherichia coli proteins MinD and MinE direct cell division to the region between the chromosomes. Several quantitative models of the Min system have been suggested before, but no one of them accounts for the behavior of all documented mutant phenotypes. We…
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Artikel Jurnal Teks lengkap
Identification and Analysis of Genes and Pseudogenes within Duplicated Regions in the Human and Mouse Genomes
The identification and classification of genes and pseudogenes in duplicated regions still constitutes a challenge for standard automated genome annotation procedures. Using an integrated homology and orthology analysis independent of current gene annotation, we have identified 9,484 and 9,017 gene…
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Artikel Jurnal Teks lengkap
Immunoinformatics Comes of Age
With the burgeoning immunological data in the scientific literature, scientists must increasingly rely on Internet resources to inform and enhance their work. Here we provide a brief overview of the adaptive immune response and summaries of immunoinformatics resources, emphasizing those with Web…
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Artikel Jurnal Teks lengkap
Shoot Meristem Function and Leaf Polarity: The Role of Class III HD–ZIP Genes
The shoot apical meristem comprises an organized cluster of cells with a central region population of self-maintaining stem cells providing peripheral region cells that are recruited to form differentiated lateral organs. Leaves, the principal lateral organ of the shoot, develop as polar structures…
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Artikel Jurnal Teks lengkap
Histone H3.3 Variant Dynamics in the Germline of Caenorhabditis elegans
Germline chromatin undergoes dramatic remodeling events involving histone variants during the life cycle of an organism. A universal histone variant, H3.3, is incorporated at sites of active transcription throughout the cell cycle. The presence of H3.3 in chromatin indicates histone turnover, which…
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Artikel Jurnal Teks lengkap
Secondary Outcomes of a Pilot Randomized Trial of Azithromycin Treatment for Asthma
Objectives: The respiratory pathogen Chlamydia pneumoniae (C. pneumoniae) produces acute and chronic lung infections and is associated with asthma. Evidence for effectiveness of antichlamydial antibiotics in asthma is limited. The primary objective of this pilot study was to investigate the…
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Artikel Jurnal Teks lengkap
Genetic Polymorphisms and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets
Objectives: To study if genes with common single nucleotide polymorphisms (SNPs) associated with obesity-related phenotypes influence weight loss (WL) in obese individuals treated by a hypo-energetic low-fat or high-fat diet. Design: Randomised, parallel, two-arm, open-label multi-centre trial…
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The Clinical Trials Directive: How Is It Affecting Europe's Noncommercial Research
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Artikel Jurnal Teks lengkap
The Thymus Is a Common Target Organ in Infectious Diseases
Infectious disease immunology has largely focused on the effector immune response, changes in the blood and peripheral lymphoid organs of infected individuals, and vaccine development. Studies of the thymus in infected individuals have been neglected, although this is progressively changing. The…
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Artikel Jurnal Teks lengkap
Correction: A New Bacillus anthracis Found in Wild Chimpanzees and a Gorilla from West and Central Africa
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Artikel Jurnal Teks lengkap
Listeria monocytogenes Traffics from Maternal Organs to the Placenta and Back
Infection with Listeria monocytogenes is a significant health problem during pregnancy. This study evaluates the role of trafficking between maternal organs and placenta in a pregnant guinea pig model of listeriosis. After intravenous inoculation of guinea pigs, the initial ratio of bacteria in…
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