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Stance modals in Chinese EFL learners’ monologue tasks: A corpus-based study
This study investigates how Chinese tertiary-level EFL learners used modals as linguistic devices for expressing stances in spoken English. Modals convey speakers’ commitment to propositions (epistemic stance) and intentions to affect reality (effective stance). While existing research has…
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Acceptability of Suubi+Adherence intervention to improve ART adherence in Southern Uganda: A qualitative analysis
In Uganda, 150,000 young people were living with HIV by the end of 2023. While Antiretroviral therapy (ART) is effective in reducing HIV transmission, youth in SSA, including in Uganda, face greater challenges with ART adherence compared to adults. Poverty-focused interventions have been…
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Development and validation of the MIPPE: A novel dyadic assessment tool for early parent-child interactions in clinical practice
Early parent-child interactions are crucial for child development. Existing assessment scales have several limitations: intensive training often exceeding 40 hours, administration time up to two hours, and unbalanced distribution of items to the detriment of the dyadic dimension of interactions…
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Resilient road safety modeling through spatially disaggregated explainable AI
Understanding spatial disparities in traffic accident severity is essential not only for improving transport safety but also for advancing sustainable and inclusive transportation systems. Road crashes represent a persistent public health and equity challenge, directly linked to the United Nations…
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Sorting the mind: A systematic review and meta-analysis protocol of transcutaneous auricular vagus nerve stimulation on cognitive functions
Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive neuromodulation technique that activates vagal afferents projecting to prefrontal–limbic circuits implicated in attention, memory, and emotion regulation. Preliminary studies suggest that taVNS may enhance…
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Effectiveness of community-based interventions for PTSD among youth in low- and middle-income countries affected by humanitarian emergencies: A systematic review and meta-analysis
Humanitarian emergencies expose millions of young people to adversity each year, with particularly severe consequences in low-and middle-income countries (LMICs) where mental health resources are scarce. In these contexts, community-based interventions (CBIs) can fill treatment gaps by leveraging…
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The transcription factor TaWRKY58 coordinates growth and drought sensitivity in wheat by repressing TaLRR and TaBCS1
Balancing growth and stress adaptation is essential for optimizing crop productivity, yet the transcriptional mechanisms underlying this trade-off in wheat remain poorly understood. Here, we identify the WRKY transcription factor TaWRKY58 as a key repressor coordinating plant architecture and…
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Pre-Human Immunodeficiency Virus (HIV) infection Th17 CD4 + T cells as predictors of early HIV disease progression
Interleukin-17-producing T helper (Th17) CD4+ T cells are highly susceptible to HIV infection and are depleted early in people living with HIV. Here, we investigated whether systemic Th17 cell levels prior to HIV infection are associated with subsequent HIV disease progression. We analyzed archived…
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Automating population construction and parallel simulation of biophysical models for neuromuscular cells: An inverse approach
Biophysical modeling and simulation help to promote a comprehensive understanding of the neuromuscular mechanisms underlying muscle force generation and control in normal and pathological states. However, this process is labor intensive and limited to special conditions due to the heterogeneity of…
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Baa-iov: Blockchain-enabled anonymous authentication for internet of vehicles
As a core component of intelligent transportation systems, the Internet of Vehicles (IoV) relies heavily on secure and efficient authentication mechanisms to support real-time information exchange and data sharing among network entities. However, traditional centralized authentication schemes…
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Effect of psychoeducation in reducing caregiver burden among family caregivers of people with mental disorders in Western Ethiopia, 2021–2022: A pre-test post-test study
Background: Family caregivers of individuals with mental disorders experience significant financial, emotional, and psychological burden, particularly in low-resource settings with limited access to formal mental health services. Although psychoeducation is an effective strategy for reducing…
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Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial
We aimed to evaluate the efficacy and safety of a spore-forming probiotic blend containing Clostridium butyricum IDCC 1301, Weizmannia coagulans IDCC 1201, and Bacillus subtilis IDCC 1101 for improving bowel function and well-being in adults with functional constipation (FC). In a randomized…
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Optimization of wind-solar-gas-storage integrated energy systems under the carbon and green certificate markets
This study investigates the optimization of wind-solar-gas-storage integrated energy systems (IES) under the dual-market mechanisms of carbon emission trading (CET) and green certificate trading (GCT). A unified analytical framework is developed to examine the techno-economic and environmental…
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Prevalence of fungal infections in a patient cohort in The Gambia: Identification and characterization of three priority fungal species in patients with symptoms suggestive of TB
Invasive fungal infections are an increasing global health concern, particularly in low-resource settings where diagnostic capacity is limited. In The Gambia, where tuberculosis is highly prevalent, fungal infections may be misdiagnosed as mycobacterial disease due to overlapping clinical symptoms…
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Predicting multiple sclerosis from radiologically isolated syndrome using generative artificial intelligence
Radiologically Isolated Syndrome (RIS) is characterized by incidental MRI findings indicative of multiple sclerosis (MS) in asymptomatic individuals. Factors such as younger age, positive cerebrospinal fluid biomarkers, and specific lesion locations have been previously linked to a higher risk of…
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Sustainable preservation of dried fish using hybridized plant extracts: HPLC-based quantification of aflatoxins and vitamins, and assessment of broad-spectrum antimicrobial efficacy
This research aimed to preserve the nutritional qualities of fish flesh during prolonged storage, by utilizing bioactive compounds derived from plant extracts and oils. Fish flesh (tissues) was treated with lime, ginger, turmeric, banana peel extracts, and oils – including their hybridized forms…
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LAMAS (Light, Activity, Meals, & Sleep) timings & burnout, anxiety, and depression in teachers: Protocol for a cross-sectional study
Background: Teachers play a key role in society and make up ~1.5–2.5% of the working population. Yet, there is a teacher shortage in many countries and preventive occupational medicine strategies are called for. The primary objective of this project is to explore single and joint associations of…
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An online stigma reduction education program for healthcare workers working with people who inject drugs: Development
Canada has a high prevalence of people who inject drugs (PWID), many of whom experience limited access to necessary diagnosis, treatment, and support. PWID often avoid seeking care due to stigma from healthcare workers (HCWs). Implementing a stigma reduction education program for HCWs could improve…
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Gut microbiome alterations among Ghanaian children with asymptomatic malaria infections
The human gut microbiome, consisting of bacteria, archaea, fungi, and viruses, influences various physiological processes of the body. The gut microbiome composition is shaped by factors such as diet, geography, and antibiotic use. Malaria has been a global health challenge over the years…
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Protocol for a randomized pilot trial of COMPASS, an open‑source, culturally adapted cognitive behavioral therapy program for forcibly displaced Venezuelan adults in Peru
Task-sharing approaches have shown promise in low-resource settings, yet few culturally adapted interventions have been systematically evaluated for forcibly displaced populations. Since 2016, over 1.7 million Venezuelans have migrated to Peru, facing significant barriers to healthcare and elevated…
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