10 results for "Daniel Simancas-Racines"
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H5N1 Avian Influenza: A Narrative Review of Scientific Advances and Global Policy Challenges
The H5N1 avian influenza virus continues to evolve into genetically diverse and highly pathogenic clades with increased potential for cross-species transmission. Recent scientific advances have included the development of next-generation vaccine platforms, promising antiviral compounds, and more…
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Evaluación crítica de la Guía de Práctica Clínica para malaria de la OMS utilizando el instrumento AGREE II
Objetivo: Evaluar críticamente la calidad metodológica de la Guía de Práctica Clínica para malaria de la Organización Mundial de la Salud. Metodología: Tres revisores de forma independiente utilizaron el instrumento AGREE II para evaluar la calidad metodológica de la Guía de Práctica Clínica para…
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Spatiotemporal clustering and epidemiological characterization of suicides in Ecuador, 2015–2023
Suicide is an important public health issue worldwide, especially among the young population. This study aimed to analyze the epidemiological characteristics and the spatial and temporal distribution of suicide at the provincial level in Ecuador between 2015 and 2023, using national mortality…
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Avian Influenza: Strategies to Manage an Outbreak
Avian influenza (AI) is a contagious disease among the poultry population with high avian mortality, which generates significant economic losses and elevated costs for disease control and outbreak eradication. AI is caused by an RNA virus part of the Orthomyxoviridae family; however, only…
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Medicina Basada en la Evidencia. Lectura Crítica de “Guías de Práctica Clínica”
Las guías de práctica clínica (GPC) son documentos que incluyen recomendaciones basadas en la evidencia científica para la toma de decisiones clínicas; al mismo tiempo, pueden desempeñar un papel importante en la elaboración de políticas de salud. Por lo tanto, es crucial que se evalúe críticamente…
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Liquid Biopsy and Multi-Omic Biomarkers in Breast Cancer: Innovations in Early Detection, Therapy Guidance, and Disease Monitoring
Liquid biopsy and multi-omic biomarker integration are transforming precision oncology in breast cancer, providing real-time, minimally invasive insights into tumor biology. By analyzing circulating tumor DNA, circulating tumor cells, exosomal non-coding RNAs, and proteomic or metabolomic profiles…
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False-negative results of initial RT-PCR assays for COVID-19: A systematic review
Background: A false-negative case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is defined as a person with suspected infection and an initial negative result by reverse transcription-polymerase chain reaction (RT-PCR) test, with a positive result on a subsequent test…
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Bioactive Natural Compounds in Triple-Negative Breast Cancer: Molecular Targets and Therapeutic Perspectives
Triple-negative breast cancer represents one of the most aggressive and therapeutically challenging subtypes of breast malignancies, characterized by marked biological heterogeneity, rapid progression, and limited targeted treatment options. Conventional therapies are frequently constrained by drug…
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Recommendations for SARS-CoV-2/COVID-19 testing: a scoping review of current guidance
Background Testing used in screening, diagnosis and follow-up of COVID-19 has been a subject of debate. Several organisations have developed formal advice about testing for COVID-19 to assist in the control of the disease. We collated, delineated and appraised current worldwide recommendations…
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Preferences of ICT among Patients with Chronic Kidney Disease Undergoing Hemodialysis: An Ecuadorian Cross-Sectional Study
ObjectivesThe aim of the present study was to assess the frequency of use, and preferences regarding information and communication technologies (ICTs) among Ecuadorian patients with chronic kidney disease (CKD) undergoing hemodialysis.MethodsWe conducted an anonymous cross-sectional survey-based…