20 hasil untuk "Burhan TURGUT"

Measurable Residual Disease in Chronic Lymphocytic Leukemia: Experience in Real-Life Setting with Dry Tube Flow Cytometric Method

Seval AKPINAR; Burhan TURGUT

Namık Kemal Tıp Dergisi, Vol. 10 No. 2 · 2022 · Turki · DOAJ Scopus

Aim:Undetectable measurable residual disease (uMRD) after chemoimmunotherapy (CI) is associated longer progression-free survival (PFS) and overall survival. However, it remains to be demonstrated whether uMRD translates into survival benefit in patients treated outside of clinical trials…

HAIR REPIGMENTATION IN AN OLDER PATIENT TREATED WITH ASCIMINIB

Burcu Altındağ Avcı; Burhan Turgut

Hematology, Transfusion and Cell Therapy, Vol. 46 · 2024 · Inggris · DOAJ Scopus

Objective: Asciminib may be a promising treatment option for intolerance of tyrosine kinase inhibitors (TKIs). It is a first-in-class inhibitor with a more selective mechanism of action different from the ATP-competitive inhibition that occurs with TKIs. Adverse effects (AEs) related to the…

Mutation Analysis in Iron Deficiency Anemia of Undeterminable Etiology

Banu Çiçek Yalçın Dulundu; Burhan Turgut

Namık Kemal Tıp Dergisi, Vol. 4 No. 3 · 2016 · Turki · DOAJ Scopus

Iron deficiency is the main cause of anemia worldwide. Iron deficiency anemia (IDA) occurs under such conditions as insufficient intake (when requirements increase or under normal conditions) or when losses cannot be met by intake. IDA may also rarely be seen in rare situations such as when…

Comparative Analysis of Cell Dilution Assays for Single-Cell Colony Formation in CRISPR-Mediated Knockout Screening

Hülya Dönmez; Bahadır Batar; Burhan Turgut

Cyprus Journal of Medical Sciences, Vol. 11 No. 1 · 2026 · Inggris · DOAJ

BACKGROUND/AIMS: The ribonucleic acid (RNA)-guided Cas9 nuclease from the microbial clustered regularly interspaced palindromic repeats (CRISPR) immune system enables genome editing in eukaryotic cells by using a 20-nucleotide target sequence guide RNA. A key CRISPR technique is the ability to…

Chronic Lymphocytic Leukemia With Central Nervous Involvement In The Form of Localized Mass Responding to Therapy With Fludarabine

Burhan Turgut; Gülsüm Emel Pamuk; Nilda Turgut dkk.

Neuropsychiatric Investigation, Vol. 45 No. 2 · 2007 · Inggris · DOAJ Scopus

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Social Navigation in Warehouse Logistics Based on Artificial Intelligence and RGB-D

Burhan Turgut Ulutürk; Emre Sebat; Hilal Öztemel dkk.

Verimlilik Dergisi, Vol. 59 No. 2 · 2025 · Turki · DOAJ

Purpose: Ensuring both human safety and transportation efficiency simultaneously during the navigation of autonomous mobile robots (AMRs) in warehouse logistics is a challenging problem due to dynamic environments and diverse obstacles. In this study, a social navigation approach based on…

The Diagnostic Utility of Flow Cytometry in Celiac Disease Presented Isolated Iron Deficiency Anemia

Rafet Mete; Mustafa Oran; Burcu Altındağ Avcı dkk.

The Turkish Journal of Gastroenterology, Vol. 32 No. 11 · 2021 · Inggris · DOAJ Scopus

Background: Flow cytometric analysis of intestinal intraepithelial lymphocytes contributes to the diagnosis of celiac disease. Celiac disease may present with iron deficiency anemia alone which is considered as one of the forms of atypical celiac disease. In this study, we have aimed to investigate…

Contribution of Leukocyte Platelet Aggregates To Development of Thrombosis In Patients With Advanced Cancer

Burcu AVCI; Okan AVCI; Dilek SOLMAZ dkk.

Namık Kemal Tıp Dergisi, Vol. 5 No. 1 · 2017 · Turki · DOAJ Scopus

Objective:The aim of our study was to determine the correlation between leukocyte platelet aggregates and thrombosis in patients with solid tumors who are susceptible to inflammation and thrombosis.Material and Method:In this study, we compared laboratory and clinical data of 28 metastatic…

Association of WWOX Gene Expression with Chronic Lymphocytic Leukemia

Halil HANCI; Birol TOPÇU; Seval AKPINAR dkk.

Namık Kemal Tıp Dergisi, Vol. 8 No. 2 · 2020 · Turki · DOAJ Scopus

Aim:The WW domain-containing oxidoreductase (WWOX) gene is located on chromosome 16q23.3-q24.1 and contains the common chromosomal fragile site, FRA16D. The WWOX gene encodes a Wwox tumor suppressor protein with a molecular weight of 46 kDa. Loss of heterozygosity (LOH) at the WWOX locus, promoter…

Retrospective Evaluation of Patients Diagnosed with Diffuse Large B Cell Lymphoma (DLBCL)

Atakan TEKİNALP; Sinan DEMİRCİOĞLU; Volkan KARAKUŞ dkk.

Namık Kemal Tıp Dergisi, Vol. 8 No. 3 · 2020 · Turki · DOAJ Scopus

Aim: Diffuse Large B Cell Lymphoma (DLBCL) is the most common NHL and %80 of all NHLs. Although it has some subtypes with heterogenous characteristic for prognosis, in area of rituximab monoclonal anti-body, improvement in overall survival (OS) was achieved. We evaluated response of treatment…

Validation and Modeling of Flow Cytometric CD36 Coefficient of Variation Analysis in the Diagnosis of Lower-Risk Myelodysplastic Syndrome

Emre Akar; Şüheda Çakmak; Mehmet Baysal dkk.

Turkish Journal of Hematology, Vol. 43 No. 2 · 2026 · Inggris · DOAJ Scopus

Objective: Myelodysplastic syndrome (MDS) constitutes a group of clonal hematopoietic disorders in which flow cytometry plays a limited yet evolving role in diagnosis. Recent studies have identified the CD36 coefficient of variation (CV) as a potential marker of dyserythropoiesis. This study aimed…

The Diagnosis of Multiple Myeloma With Macroglossia and Edema Symptoms

Sonat Pınar Kara; Atakan Tekinalp; Bülent Bilir dkk.

Southern Clinics of Istanbul Eurasia, Vol. 28 No. 1 · 2017 · Inggris · DOAJ

In this case, the importance of multiple myeloma in differential diagnosis of non-specific symptoms, such as macroglossia and significant pretibial edema, is highlighted. A 44-year-old male presented to the internal medicine outpatient clinic with complaints of ongoing and increasing enlargement of…

Obese Subjects Have Low Global Fibrinolytic Capacity Associated with Insulin Resistance

Burhan Turgut; Sibel Güldiken; Muzaffer Demir dkk.

Endocrinology Research and Practice, Vol. 10 No. 2 · 2006 · Inggris · DOAJ Scopus

Abstract Obese subjects frequently have insulin resistance and they are at particularly risk of cardiovascular complications, possibly related to haemostatic and fibrinolytic system dysfunction. The aim of this study was to determine the effects of obesity on global fibrinolytic capacity (GFC)…

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Myxoma Virus Combination Therapy Enhances Lenalidomide and Bortezomib Treatments for Multiple Myeloma

Alpay Yeşilaltay; Dilek Muz; Berna Erdal dkk.

Pathogens, Vol. 13 No. 1 · 2024 · Inggris · DOAJ Scopus

This study aimed to explore the effectiveness and safety of Myxoma virus (MYXV) in MM cell lines and primary myeloma cells obtained from patients with multiple myeloma. Myeloma cells were isolated from MM patients and cultured. MYXV, lenalidomide, and bortezomib were used in MM cells. The…

Acute Lymphoblastic Leukemia in Routine Practice: A Turkish Multicenter Study

Rafiye Çiftçiler; Omur Gokmen Sevindik; Ali İrfan Emre Tekgündüz dkk.

Turkish Journal of Hematology, Vol. 36 No. 3 · 2019 · Inggris · DOAJ Scopus

Objective: Significant developments occurred in the clinical management of acute lymphoblastic leukemia (ALL) in adults in recent decades. However, treatment results are still not satisfactory, especially in routine practice. The objective of this study was to evaluate the general clinical…

Immune Thrombotic Thrombocytopenic Purpura in Elderly Patients: The Roles of PLASMIC and French Scores

Mehmet Baysal; Fehmi Hindilerden; Elif Gülsüm Umit dkk.

Turkish Journal of Hematology, Vol. 40 No. 4 · 2023 · Inggris · DOAJ Scopus

Objective: In recent years, new developments have been incorporated into daily practice in the management of immune thrombotic thrombocytopenic purpura (iTTP). In particular, clinical scoring systems could help clinicians with clinical decision-making and early recognition. However, older patients…

Brentuximab Vedotin Monotherapy in Relapsed/Refractory T Cell Lymphoma Setting-Real Life Data

Tahir Darcın; Istemi Serın; Mehmet Can Ugur dkk.

Hitit Medical Journal, Vol. 6 No. 2 · 2024 · Turki · DOAJ

Objective: We present data of patients with relapsed/ refractory T cell lymphomas treated with brentuximab vedotin (BV) in real-world practice. Material and Method: This study is an observational, multi-center, retrospective study. The data of patients (n=17) treated with BV alone from January 2014…

A Real-Life Turkish Experience of Ruxolitinib in Polycythemia Vera

İstemi Serin; Mehmet Hilmi Doğu; Ömer Ekinci dkk.

İstanbul Medical Journal, Vol. 24 No. 2 · 2023 · Inggris · DOAJ Scopus

Introduction:Ruxolitinib is a small -molecule inhibitor of the JAK1/2 pathway. This study aimed to reveal the results and side-effect profile of the use of ruxolitinib as a treatment option in polycythemia vera (PV).Methods:A total of 34 patients with PV from 18 different centers were included in…

Efficacy and Safety of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia: Retrospective Analysis of Real-Life Data

Anıl Tombak; Funda Pepedil Tanrıkulu; Salih Sertaç Durusoy dkk.

Turkish Journal of Hematology, Vol. 38 No. 4 · 2021 · Inggris · DOAJ Scopus

Objective: This study aimed to retrospectively evaluate the efficacy, safety, and survival outcome of single-agent ibrutinib therapy in chronic lymphocytic leukemia patients. Materials and Methods: A total of 136 patients (mean age +- standard deviation: 64.6+-10.3 years, 66.9% males) who had…