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9 hasil untuk "Carsen Stringer"

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  1. Artikel Jurnal

    Cellpose3: one-click image restoration for improved cellular segmentation

    Carsen Stringer; Marius Pachitariu

    Nature Methods · 2025 · Inggris · OpenAlex Scopus

    Generalist methods for cellular segmentation have good out-of-the-box performance on a variety of image types; however, existing methods struggle for images that are degraded by noise, blurring or undersampling, all of which are common in microscopy. We focused the development of Cellpose3 on…

  2. Artikel Jurnal Teks lengkap

    Cellpose 2.0: how to train your own model

    Marius Pachitariu; Carsen Stringer

    Nature Methods · 2022 · Inggris · OpenAlex Scopus

    Pretrained neural network models for biological segmentation can provide good out-of-the-box results for many image types. However, such models do not allow users to adapt the segmentation style to their specific needs and can perform suboptimally for test images that are very different from the…

  3. Artikel Jurnal Teks lengkap

    Spike sorting with Kilosort4

    Marius Pachitariu; Shashwat Sridhar; Jacob R. Pennington dkk.

    Nature Methods · 2024 · Inggris · OpenAlex Scopus

    Spike sorting is the computational process of extracting the firing times of single neurons from recordings of local electrical fields. This is an important but hard problem in neuroscience, made complicated by the nonstationarity of the recordings and the dense overlap in electrical fields between…

  4. Artikel Jurnal

    A simplified minimodel of visual cortical neurons

    Fengtong Du; Miguel Angel Núñez-Ochoa; Marius Pachitariu dkk.

    Nature Communications, Vol. 16 No. 1 · 2025 · Inggris · DOAJ Scopus

    Abstract Artificial neural networks (ANNs) have been shown to predict neural responses in primary visual cortex (V1) better than classical models. However, this performance often comes at the expense of simplicity and interpretability. Here we introduce a new class of simplified ANN models that can…

  5. Artikel Jurnal Teks lengkap

    Brainwide hemodynamics predict EEG neural rhythms across sleep and wakefulness in humans

    Leandro P. L. Jacob; Sydney M. Bailes; Stephanie D. Williams dkk.

    PLOS Computational Biology, Vol. 21 No. 9 · 2025 · Inggris · PLOS Scopus

    The brain exhibits rich oscillatory dynamics that play critical roles in vigilance and cognition, such as the neural rhythms that define sleep. These rhythms continuously fluctuate, signaling major changes in vigilance, but the widespread brain dynamics underlying these oscillations are difficult…

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  6. Artikel Jurnal Teks lengkap

    Omnipose: a high-precision morphology-independent solution for bacterial cell segmentation

    Kevin J. Cutler; Carsen Stringer; Teresa W. Lo dkk.

    Nature Methods · 2022 · Inggris · OpenAlex Scopus

    Advances in microscopy hold great promise for allowing quantitative and precise measurement of morphological and molecular phenomena at the single-cell level in bacteria; however, the potential of this approach is ultimately limited by the availability of methods to faithfully segment cells…

  7. Artikel Jurnal

    Inhibitory control of correlated intrinsic variability in cortical networks

    Carsen Stringer; Marius Pachitariu; Nicholas A Steinmetz dkk.

    eLife, Vol. 5 · 2016 · Inggris · DOAJ

    Cortical networks exhibit intrinsic dynamics that drive coordinated, large-scale fluctuations across neuronal populations and create noise correlations that impact sensory coding. To investigate the network-level mechanisms that underlie these dynamics, we developed novel computational techniques…