17 results for "Cheng He"

Using LiDAR Data to Measure the 3D Green Biomass of Beijing Urban Forest in China

Cheng He; Matteo Convertino; Zhongke Feng et al.

PLoS ONE, Vol. 8 No. 10 · 2013 · English · PLOS Scopus

The purpose of the paper is to find a new approach to measure 3D green biomass of urban forest and to testify its precision. In this study, the 3D green biomass could be acquired on basis of a remote sensing inversion model in which each standing wood was first scanned by Terrestrial Laser Scanner…

K V 7/KCNQ Channels Are Functionally Expressed in Oligodendrocyte Progenitor Cells

Wei Wang; Xiao-Fei Gao; Lin Xiao et al.

PLoS ONE, Vol. 6 No. 7 · 2011 · English · PLOS Scopus

Background: KV7/KCNQ channels are widely expressed in neurons and they have multiple important functions, including control of excitability, spike afterpotentials, adaptation, and theta resonance. Mutations in KCNQ genes have been demonstrated to associate with human neurological pathologies…

Nitrated α-Synuclein Induces the Loss of Dopaminergic Neurons in the Substantia Nigra of Rats

Zhongwang Yu; Xiaohui Xu; Zhenghua Xiang et al.

PLoS ONE, Vol. 5 No. 4 · 2010 · English · PLOS Scopus

Background: The pathology of Parkinson's disease (PD) is characterized by the degeneration of the nigrostriatal dopaminergic pathway, as well as the formation of intraneuronal inclusions known as Lewy bodies and Lewy neurites in the substantia nigra. Accumulations of nitrated α-synuclein are…

Reactive Astrocytes in Glial Scar Attract Olfactory Ensheathing Cells Migration by Secreted TNF-α in Spinal Cord Lesion of Rat

Zhida Su; Yimin Yuan; Jingjing Chen et al.

PLoS ONE, Vol. 4 No. 12 · 2009 · English · PLOS Scopus

Background: After spinal cord injury (SCI), the formation of glial scar contributes to the failure of injured adult axons to regenerate past the lesion. Increasing evidence indicates that olfactory ensheathing cells (OECs) implanted into spinal cord are found to migrate into the lesion site and…

Cyclone exposure and mortality risk of children under 5 years old: An observational study in 34 low- and middle-income countries

Yichen Guo; Yixiang Zhu; Cheng He et al.

PLOS Medicine, Vol. 22 No. 9 · 2025 · English · PLOS Scopus

Background: Climate change has exacerbated the frequency, intensity, and impacts of extreme weather events (EWEs), such as tropical cyclones. However, the increasing impact of tropical cyclones on child mortality, especially in low- and middle-income countries (LMICs), remains understudied. Methods…

Protocatechuic Acid, a Novel Active Substance against Avian Influenza Virus H9N2 Infection

Changbo Ou; Ningning Shi; Qunhui Yang et al.

PLoS ONE, Vol. 9 No. 10 · 2014 · English · PLOS Scopus

Influenza virus H9N2 subtype has triggered co-infection with other infectious agents, resulting in huge economical losses in the poultry industry. Our current study aims to evaluate the antiviral activity of protocatechuic acid (PCA) against a virulent H9N2 strain in a mouse model. 120 BALB/c mice…

SHP-2 Promotes the Maturation of Oligodendrocyte Precursor Cells Through Akt and ERK1/2 Signaling In Vitro

Xiujie Liu; Yuanyuan Li; Yong Zhang et al.

PLoS ONE, Vol. 6 No. 6 · 2011 · English · PLOS Scopus

Background: Oligodendrocyte precursor cells (OPCs) differentiate into oligodendrocytes (OLs), which are responsible for myelination. Myelin is essential for saltatory nerve conduction in the vertebrate nervous system. However, the molecular mechanisms of maturation and myelination by…

A Gene-Oriented Haplotype Comparison Reveals Recently Selected Genomic Regions in Temperate and Tropical Maize Germplasm

Cheng He; Junjie Fu; Jie Zhang et al.

PLOS ONE, Vol. 12 No. 1 · 2017 · English · PLOS Scopus

The extensive genetic variation present in maize (Zea mays) germplasm makes it possible to detect signatures of positive artificial selection that occurred during temperate and tropical maize improvement. Here we report an analysis of 532,815 polymorphisms from a maize association panel consisting…

Dimethyl itaconate ameliorates the deficits of goal-directed behavior in Toxoplasma gondii infected mice

Yongshuai Wu; Daxiang Xu; Yan He et al.

PLOS Neglected Tropical Diseases, Vol. 17 No. 5 · 2023 · English · PLOS Scopus

Background: The neurotrophic parasite Toxoplasma gondii (T. gondii) has been implicated as a risk factor for neurodegenerative diseases. However, there is only limited information concerning its underlying mechanism and therapeutic strategy. Here, we investigated the effects of T. gondii chronic…

Gender Differences and Effect of Air Pollution on Asthma in Children with and without Allergic Predisposition: Northeast Chinese Children Health Study

Guang-Hui Dong; Tao Chen; Miao-Miao Liu et al.

PLoS ONE, Vol. 6 No. 7 · 2011 · English · PLOS Scopus

Background: Males and females exhibit different health responses to air pollution, but little is known about how exposure to air pollution affects juvenile respiratory health after analysis stratified by allergic predisposition. The aim of the present study was to assess the relationship between…

Construction of Recombinant HVT Expressing PmpD, and Immunological Evaluation against Chlamydia psittaci and Marek’s Disease Virus

Shanshan Liu; Wei Sun; Jun Chu et al.

PLOS ONE, Vol. 10 No. 4 · 2015 · English · PLOS Scopus

Chlamydia psittaci (C. psittaci) is an obligate intracellular zoonotic pathogen that can be transmitted to humans from birds. No efficacious commercial vaccine is available for clearing chlamydial infection due to lack of potential vaccine candidates and effective delivery vehicles. Herpesvirus of…

Predictive Equations Using Regression Analysis of Pulmonary Function for Healthy Children in Northeast China

Ya-Nan Ma; Jing Wang; Guang-Hui Dong et al.

PLoS ONE, Vol. 8 No. 5 · 2013 · English · PLOS Scopus

Background: There have been few published studies on spirometric reference values for healthy children in China. We hypothesize that there would have been changes in lung function that would not have been precisely predicted by the existing spirometric reference equations. The objective of the…

Climate and health at a critical juncture

Zerina Lokmic-Tomkins; Azar Abadi; Tarik Benmarhnia et al.

PLOS Climate, Vol. 5 No. 4 · 2026 · English · PLOS Scopus

Lysophosphatidic Acid Acyltransferase β (LPAATβ) Promotes the Tumor Growth of Human Osteosarcoma

Farbod Rastegar; Jian-Li Gao; Deana Shenaq et al.

PLoS ONE, Vol. 5 No. 12 · 2010 · English · PLOS Scopus

Background: Osteosarcoma is the most common primary malignancy of bone with poorly characterized molecular pathways important in its pathogenesis. Increasing evidence indicates that elevated lipid biosynthesis is a characteristic feature of cancer. We sought to investigate the role of…

Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential

Enyi Huang; Yang Bi; Wei Jiang et al.

PLoS ONE, Vol. 7 No. 2 · 2012 · English · PLOS Scopus

Mesenchymal stem cells (MSCs) are multipotent cells which reside in many tissues and can give rise to multiple lineages including bone, cartilage and adipose. Although MSCs have attracted significant attention for basic and translational research, primary MSCs have limited life span in culture…

Correction: Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential

Enyi Huang; Yang Bi; Wei Jiang et al.

PLoS ONE, Vol. 8 No. 1 · 2013 · English · PLOS Scopus

Retinoic Acids Potentiate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells

Wenli Zhang; Zhong-Liang Deng; Liang Chen et al.

PLoS ONE, Vol. 5 No. 7 · 2010 · English · PLOS Scopus

Background: As one of the least studied bone morphogenetic proteins (BMPs), BMP9 is one of the most osteogenic BMPs. Retinoic acid (RA) signaling is known to play an important role in development, differentiation and bone metabolism. In this study, we investigate the effect of RA signaling on…