16 hasil untuk "DEVRAJ"
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Artikel Jurnal Teks lengkap
Land use change affects water erosion in the Nepal Himalayas
Soil erosion is a global environmental threat, and Land Use Land Cover Changes (LUCC) have significant impacts on it. Nepal, being a mountainous country, has significant soil erosion issues. To examine the effects of LUCC on water erosion, we studied the LUCC in Sarada, Rapti and Thuli Bheri river…
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Digital soil mapping in the Bara district of Nepal using kriging tool in ArcGIS
Digital soil mapping has been widely used to develop statistical models of the relationships between environmental variables and soil attributes. This study aimed at determining and mapping the spatial distribution of the variability in soil chemical properties of the agricultural floodplain lands…
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p53 Target Gene SMAR1 Is Dysregulated in Breast Cancer: Its Role in Cancer Cell Migration and Invasion
Tumor suppressor SMAR1 interacts and stabilizes p53 through phosphorylation at its serine-15 residue. We show that SMAR1 transcription is regulated by p53 through its response element present in the SMAR1 promoter. Upon Doxorubicin induced DNA damage, acetylated p53 is recruited on SMAR1 promoter…
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Birth preparedness and complication readiness knowledge, practices and its associated factors among recently delivered women: A cross-sectional study in Bharatpur, Chitwan, Nepal
Background: Birth preparedness and complication readiness (BPCR) is a comprehensive strategy, aimed at ensuring that expectant mothers and their families are for normal delivery and preparing for potential complications that may arise during pregnancy, labor, delivery, and the postpartum period…
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Analgesic and Anti-Inflammatory Properties of Gelsolin in Acetic Acid Induced Writhing, Tail Immersion and Carrageenan Induced Paw Edema in Mice
Plasma gelsolin levels significantly decline in several disease conditions, since gelsolin gets scavenged when it depolymerizes and caps filamentous actin released in the circulation following tissue injury. It is well established that our body require/implement inflammatory and analgesic responses…
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Trends and outcomes of non-primary PCI at sites without cardiac surgery on-site: The early Michigan experience
Introduction: Non-primary percutaneous coronary intervention (non-PPCI) recently received certificate of need approval in the state of Michigan at sites without cardiac surgery on-site (cSoS). This requires quality oversight through participation in the BMC2 registry. While previous studies have…
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Emergence of Orientia tsutsugamushi as an important cause of Acute Encephalitis Syndrome in India
Background: Acute Encephalitis Syndrome (AES) is a major seasonal public health problem in Bihar, India. Despite efforts of the Bihar health department and the Government of India, burden and mortality of AES cases have not decreased, and definitive etiologies for the illness have yet to be…
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Predicting 30-day hospital readmissions using artificial neural networks with medical code embedding
Reducing unplanned readmissions is a major focus of current hospital quality efforts. In order to avoid unfair penalization, administrators and policymakers use prediction models to adjust for the performance of hospitals from healthcare claims data. Regression-based models are a commonly utilized…
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Prevalence of coronary risk factors in contemporary practice among patients undergoing their first percutaneous coronary intervention: Implications for primary prevention
Background: Cigarette smoking, hypertension, dyslipidemia, diabetes, and obesity are conventional risk factors (RFs) for coronary artery disease (CAD). Population trends for these RFs have varied in recent decades. Consequently, the risk factor profile for patients presenting with a new diagnosis…
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Association between socioeconomic position and cardiovascular disease risk factors in rural north India: The Solan Surveillance Study
Background: Although most Indians live in rural settings, data on cardiovascular disease risk factors in these groups are limited. We describe the association between socioeconomic position and cardiovascular disease risk factors in a large rural population in north India. Methods: We performed…
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Trends and outcomes of percutaneous coronary intervention during the COVID-19 pandemic in Michigan
Background: The COVID-19 pandemic has severely impacted healthcare delivery and patient outcomes globally. Aims: We aimed to evaluate the influence of the COVID-19 pandemic on the temporal trends and outcomes of patients undergoing percutaneous coronary intervention (PCI) in Michigan. Methods: We…
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Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro
Reproducing the characteristics and the functional responses of the blood–brain barrier (BBB) in vitro represents an important task for the research community, and would be a critical biotechnological breakthrough. Pharmaceutical and biotechnology industries provide strong demand for inexpensive…
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Cause and preventability of in-hospital mortality after PCI: A statewide root-cause analysis of 1,163 deaths
Background: Mortality is the most devastating complication of percutaneous coronary interventions (PCI). Identifying the most common causes and mechanisms of death after PCI in contemporary practice is an important step in further reducing periprocedural mortality. Objectives: To systematically…
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Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation
When stimulated by inflammation, peripheral blood cells signal directly to neurons in the brain via the transfer of functional RNA enclosed in extracellular vesicles. Mechanisms behind how the immune system signals to the brain in response to systemic inflammation are not fully understood…
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Racial and ethnic disparities in diagnosis, management and outcomes of aortic stenosis in the Medicare population
Importance: Aortic stenosis (AS) is one of the most common heart valve conditions and its incidence and prevalence increases with age. With the introduction of transcatheter aortic valve replacement (TAVR), racial and ethnic disparities in AS diagnosis, treatment and outcomes is poorly understood…
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Assessing a multicomponent quality improvement strategy for chronic care of cardiovascular diseases in India: The C-QIP randomized feasibility trial
Background: Chronic cardiovascular diseases (CVD) care quality remains suboptimal, globally. We assessed the feasibility, acceptability, fidelity, and preliminary effect of a multicomponent, collaborative quality improvement (C-QIP) strategy among patients with CVD attending outpatient clinics in…