64 hasil untuk "Deepesh Kumar"
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Machine Learning Strategies for Drug Discovery in AML: Focus on RUNX1 Bioactivity
Acute myeloid leukemia (AML) is an aggressive blood cancer where immature stem cells in the bone marrow multiply rapidly, disrupting blood cell production and leading to infections, anemia, and bleeding [...]
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Biodegradation of LDPE-based Vegetable Packaging Films through Bacteria Isolated from a Waste Disposal Site
Low density polyethylene (LDPE) is widely used plastic and its use has increased over the past few decades due to its extensive properties. The increased use of plastic generates an increasing amount of plastic waste making waste management more challenging and ultimately contributing to plastic…
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Diagnostic Utility of Target Genes 19 kDa Gene, TRC4 Element, MPB64 Gene and 32 kDa Gene in the Diagnosis of Female Genital Tuberculosis
Background: The prevalence, morbidity and mortality due to tuberculosis are high worldwide, particularly in developing countries. The extra-pulmonary tuberculosis is a diagnostic challenge due to paucibacillary nature. The female genital tuberculosis, a chronic disease, presents with atypical…
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Bacterial Extracellular Polymers: A Review
Prokaryotic microbial cells especially bacteria are highly emphases for their exopolysaccharides (EPS) production. EPS are the higher molecular weight natural extracellular compounds observe at the surface of the bacterial cells. Nowadays bacterial EPS represent rapidly emerging as new and…
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Audio-visual stimulation in conjunction with functional electrical stimulation to address upper limb and lower limb movement disorder
Neurological disorders often manifest themselves in the form of movement deficit on the part of the patient. Conventional rehabilitation often used to address these deficits, though powerful are often monotonous in nature. Adequate audio-visual stimulation can prove to be motivational. In the…
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Role of Real Time Polymerase Chain Reaction Targeting mpb64 Gene in the Diagnosis of Genitourinary Tuberculosis: A Cross-sectional Study
Introduction: Genitourinary Tuberculosis (GUTB) remains an important cause of infertility in India. The clinical manifestations of GUTB are non specific, resulting in delayed diagnosis and initiation of Anti Tubercular Treatment (ATT). This delay can lead to various complications such as kidney…
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RUNX1-Regulated Pathways and Biomarkers in Acute Myeloid Leukaemia
Runt-related transcription factor 1 gene (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), plays a crucial role in the pathogenesis of AML. RUNX1/AML1 is one of the most frequently mutated leukaemias associated with a poor prognosis in AML. Researchers and clinicians can develop…
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Virtual reality-based balance training system augmented with operant conditioning paradigm
Abstract Background Stroke-related sensory and motor deficits often steal away the independent mobility and balance from stroke survivors. Often, this compels the stroke survivors to rely heavily on their non-paretic leg during weight shifting to execute activities of daily living (ADL), with…
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Engagement sensitive visual stimulation
Stroke is one of leading cause of death and disability worldwide. Early detection during golden hour and treatment of individual neurological dysfunction in stroke using easy-to-access biomarkers based on a simple-to-use, cost-effective, clinically-valid screening tool can bring a paradigm shift in…
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Dental implant survival in diabetic patients; review and recommendations
Rising population of diabetic individuals across the world has become a big concern to the society. The persistent hyperglycemia may affect each and every tissue and consequently results in morbidity and eventually mortality in diabetic patients. A direct negative response of diabetes has been…
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Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish
Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid dysplasia (PPRD). Yet, the functional significance of CCN6 in the musculoskeletal system remains unclear. Using zebrafish as a model organism, we demonstrated that…
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Tension-induced cytokinetic abscission in human fibroblasts
Previous studies have shown that cytokinetic abscission at the end of mitosis is executed by the ESCRT machinery in mammalian cells, and that the process is dependent on adhesion-induced integrin signalling via a FAK-PLK1-CEP55-TSG101/Alix-CHMP4B pathway. The present study identified an alternative…
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WITHDRAWN: CNN Implementation for Detect Cheating in Online Exams During COVID-19 Pandemic : A CVRU Perspective
This article has been withdrawn: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been withdrawn as part of the withdrawal of the Proceedings of the International Conference on Emerging Trends in Materials…
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SuperTac - tactile data super-resolution via dimensionality reduction
The advancement of tactile sensing in robotics and prosthetics is constrained by the trade-off between spatial and temporal resolution in artificial tactile sensors. To address this limitation, we propose SuperTac, a novel tactile super-resolution framework that enhances tactile perception beyond…
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WITHDRAWN: First wave of covid-19 in India using IoT for identification of virus
This article has been withdrawn: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been withdrawn as part of the withdrawal of the Proceedings of the International Conference on Emerging Trends in Materials…
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Side effects of metal-based dental implantology treatment - A review
Titanium dental implants are widely used for their biocompatibility and mechanical strength but are vulnerable to corrosion within the oral environment. Corrosive processes such as galvanic, pitting, crevice and fretting corrosion are influenced by salivary pH, fluoride concentration, bacterial…
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Best proximity point (pair) theorem using ( α − ς ) Meir-Keeler condensing operators in Busemann convex spaces
Two new class of condensing operators, called ( α − ς ) and ( β − ς ) Meir-Keelercondensing operators, are introduced and used to investigate the existence of best proximity points (pairs) for cyclic (noncyclic) relatively nonexpansive mappings to more general metric space, namely reflexive and…
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Septin and Ras regulate cytokinetic abscission in detached cells
BACKGROUND: Integrin-mediated adhesion is normally required for cytokinetic abscission, and failure in the process can generate potentially oncogenic tetraploid cells. Here, detachment-induced formation of oncogenic tetraploid cells was analyzed in non-transformed human BJ fibroblasts and BJ…
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Characterization, Phylogenetic Analysis and Potential Applications of Heterotrophic Bacteria Inhabit Sand Dunes of Thar Desert, India
Microorganisms inhabit extreme environments are novel in terms of phylogeny and also valuable source of extracellular hydrolytic enzymes. The present study focused on isolation and characterization of moderately thermophilic heterotrophic bacteria from Thar Desert using culture dependent method and…