5 hasil untuk "Devan Patel"
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Artikel Jurnal
CXCL1: a novel therapeutic target to increase aneurysm healing after coil embolization
ObjectiveCXCL1 is highly expressed in human aneurysms but its role in aneurysm healing is unknown. The objective of this study was to determine whether CXCL1 neutralization increases murine aneurysm healing post-coiling.MethodsCarotid artery aneurysms were created in female and male C57BL/6 mice…
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Artikel Jurnal Teks lengkap
Traumatic Brain Injury and Secondary Neurodegenerative Disease
Traumatic brain injury (TBI) is a devastating event with severe long-term complications. TBI and its sequelae are one of the leading causes of death and disability in those under 50 years old. The full extent of secondary brain injury is still being intensely investigated; however, it is now clear…
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Artikel Jurnal Teks lengkap
Spinal cord injury and neurogenic lower urinary tract dysfunction: what do we know and where are we going?
One of the well reported but difficult to manage symptoms of spinal cord injury (SCI) is neurogenic lower urinary tract dysfunction (NLUTD). The type of NLUTD is variable based on location and extent of injury. SCI affects more males and NLUTD is especially debilitating for men with incomplete…
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Artikel Jurnal
Neutrophils: Novel Contributors to Estrogen‐Dependent Intracranial Aneurysm Rupture Via Neutrophil Extracellular Traps
Background Intracranial aneurysms (IAs) are more prevalent in women than men, and aneurysmal subarachnoid hemorrhage disproportionately affects postmenopausal women. These sex differences suggest estrogen protects against IA progression that can lead to rupture, but the underlying mechanisms are…
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Artikel Jurnal
Subarachnoid hemorrhage-associated brain injury and neurobehavioral deficits are reversed with synthetic adropin treatment through sustained Ser1179 phosphorylation of endothelial nitric oxide synthase
BackgroundSubarachnoid hemorrhage (SAH) is a life-threatening vascular condition without satisfactory treatment options. The secreted peptide adropin is highly expressed in the human brain and has neuroprotective effects in brain injury models, including actions involving the cerebrovasculature…