594 hasil untuk "Dharmendra Kumar"
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Artikel Jurnal
Evaluation of nematophagous and biocontrol efficacy of Dactylellina phymatopaga against Meloidogyne graminicola on rice (Oryza sativa L.)
Dactylellina phymatopaga is a nematode-trapping fungus which traps, kills and parasitizes nematodes. The rice root-knot nematode, Meloidogyne graminicola, is an important plant-parasitic nematode that threatens rice production worldwide. Therefore, it is most important to find new substitute for…
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Peroxiredoxin 1, pyroptosis, and the emerging frontier in colorectal cancer therapy
Colorectal cancer (CRC) remains a major global health challenge, with high recurrence and mortality despite advances in surgery, chemotherapy, and immunotherapy. The study by He et al identifies a novel mechanism by which peroxiredoxin 1 (Prdx1) inhibits CRC progression through induction of…
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Role of Non-Coding RNAs in Post-Transcriptional Regulation of Lung Diseases
Non-coding RNAs (ncRNAs), notably microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), have recently gained increasing consideration because of their versatile role as key regulators of gene expression. They adopt diverse mechanisms to regulate transcription and translation, and thereby, the…
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Exploring the multifaceted functions of APPL in metabolism and memory using Drosophila melanogaster
Amyloid precursor protein (APP) is a single-pass transmembrane protein abundantly expressed in the central nervous system and implicated in familial Alzheimer’s disease, a progressive neurodegenerative disorder that impairs memory. Here, we investigated the role of amyloid precursor protein-like…
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Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury
Wharton’s jelly mesenchymal stem cells (WJ-MSCs) are gaining significant attention in regenerative medicine for their potential to treat degenerative diseases and mitigate radiation injuries. WJ-MSCs are more naïve and have a better safety profile, making them suitable for both autologous and…
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Evaluation of traditional ayurvedic Kadha for prevention and management of the novel Coronavirus (SARS-CoV-2) using in silico approach
Since the emergence of novel Coronavirus (SARS-CoV-2) infection in Wuhan, China in December 2019, it has now spread to over 205 countries. The ever-growing list of globally spread corona virus-19 disease (COVID-19) patients has demonstrated the high transmission rate among the human population…
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Tissue Diagnosis in Infective Spondylodiscitis by CT-Guided Spinal Biopsy: A Standard Practice before Starting Treatment
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Sclerostin silencing in human umbilical cord mesenchymal stem cells enhances bone regeneration via Wnt pathway activation
Steroid-induced avascular necrosis of the femoral head is a debilitating condition caused by prolonged glucocorticoid exposure, leading to bone death and disrupted metabolism. Current treatment options are limited, especially in late-stage disease, emphasizing the urgent need for novel regenerative…
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Gut-Derived Metabolites and Cognitive Health: Roles of Short-Chain Fatty Acids and Trimethylamine N-oxide
The gut microbiota has emerged as an important regulator of host physiology, extending well beyond digestion and metabolism. Increasing attention has focused on the gut-brain axis, a bidirectional communication network linking the gastrointestinal tract and the central nervous system. Among the…
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Some new records of katydids (Orthoptera: Tettigoniidae) from Uttar Pradesh, India
In the present investigation intensive field surveys were undertaken to explore katydids of Uttar Pradesh. Five species of katydids from four genera, namely, Letana cf. megastridula Ingrisch, 1990, Parasanaa donovani (Donovan, 1834), Sathrophyllia femorata (Fabricius, 1787), S. rugosa (Linnaeus…
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Integrating Research into Indian Undergraduate Medical Education: A Systematic Review Aligned with Competency-based Medical Education and National Medical Commission Competencies
In 2024, the National Medical Commission (NMC) of India revised its Graduate Medical Education Regulations to include “researcher” and “critical thinker” as core roles for Indian Medical Graduates, aligning with global trends in competency-based medical education (CBME). However, research training…
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Lecanemab and Donanemab in Early Alzheimer’s Disease: A Systematic Review of Clinical, Biomarker, and Safety Outcomes
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia worldwide. Characterized by amyloid-beta (Aβ) accumulation, tau pathology, and cognitive decline, it has long lacked effective disease-modifying treatments. Recently, monoclonal antibodies…
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The Role of Glucagon-Like Peptide-1 Receptor Agonists in Cognitive Decline and Dementia Prevention: A Systematic Review and Semiquantitative Synthesis
Dementia, particularly Alzheimer’s disease (AD), is a major global health challenge with limited treatment options. Growing evidence suggests that glucagon-like peptide-1 receptor agonists (GLP-1 RAs), originally developed for type 2 diabetes mellitus (T2DM), may offer neuroprotective benefits by…
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Anomalous Right Coronary Artery Originating from Mid Left Anterior Descending Artery- An Unexpected Encounter during Primary Percutaneous Coronary Intervention
The appearance of single coronary artery with anomalous Right Coronary Artery (RCA) originating from left coronary artery is an extremely rare encounter. Here, the authors report one such case of a 34-year-old male, who was serendipitously encountered with a single coronary artery with anomalous…