29 results for "Heather Draper"

Ethical challenges experienced by UK military medical personnel deployed to Sierra Leone (operation GRITROCK) during the 2014–2015 Ebola outbreak: a qualitative study

Heather Draper; Simon Jenkins

BMC Medical Ethics, Vol. 18 No. 1 · 2017 · English · DOAJ Scopus

Abstract Background As part of its response to the 2014 Ebola outbreak in west Africa, the United Kingdom (UK) government established an Ebola treatment unit in Sierra Leone, staffed by military personnel. Little is known about the ethical challenges experienced by military medical staff on…

Second thoughts about privacy, safety and deception

Tom Sorell; Heather Draper

Connection Science, Vol. 29 No. 3 · 2017 · English · DOAJ Scopus

In this paper, we point out some difficulties with interpreting three of five principles formulated at a retreat on robot ethics sponsored by the Arts and Humanities Council and the Engineering and Physical Sciences Research Council. We also attempt to iron out some conflicts between the…

A Systematic Review of Ebola Treatment Trials to Assess the Extent to Which They Adhere to Ethical Guidelines.

Thomas Richardson; Andrew McDonald Johnston; Heather Draper

PLoS ONE, Vol. 12 No. 1 · 2017 · English · DOAJ Scopus

BackgroundObjective: To determine to what extent each trial met criteria specified in three research frameworks for ethical trial conduct. Design: Systematic review and narrative analysis.Methods and findingsData sources: MEDBASE and EMBASE databases were searched using a specific search strategy…

Also available at: PLOS

Management of Patient-Reported Outcome (PRO) Alerts in Clinical Trials: A Cross Sectional Survey.

Derek Kyte; Jonathan Ives; Heather Draper et al.

PLoS ONE, Vol. 11 No. 1 · 2016 · English · DOAJ Scopus

BACKGROUND:Assessment of patient-reported outcomes (PROs) provides valuable information to inform patient-centered care, but may also reveal 'PRO alerts': psychological distress or physical symptoms that may require an immediate response. Ad-hoc management of PRO alerts in clinical trials may…

Also available at: PLOS

Potential research participants' use of information during the consent process: A qualitative pilot study of patients enrolled in a clinical trial.

Simon Paul Jenkins; Melanie J Calvert; Heather Draper

PLoS ONE, Vol. 15 No. 6 · 2020 · English · DOAJ Scopus

There is increasing evidence that clinical trial participants are uninformed about the trials in which they participate, raising ethical concerns regarding informed consent. The aim of this pilot study was to explore clinical trial participants' use of consent discussions and information sheets…

Also available at: PLOS

Informing potential participants about research: observational study with an embedded randomized controlled trial.

Helen M Kirkby; Melanie Calvert; Richard J McManus et al.

PLoS ONE, Vol. 8 No. 10 · 2013 · English · DOAJ Scopus

ObjectivesTo assess: 1) the feasibility of electronic information provision; 2) gather evidence on the topics and level of detail of information potential research participant's accessed; 3) to assess satisfaction and understanding.DesignObservational study with an embedded randomised controlled…

Also available at: PLOS

Inconsistencies in quality of life data collection in clinical trials: a potential source of bias? Interviews with research nurses and trialists.

Derek Kyte; Jonathan Ives; Heather Draper et al.

PLoS ONE, Vol. 8 No. 10 · 2013 · English · DOAJ Scopus

BACKGROUND:Patient-reported outcomes (PROs), such as health-related quality of life (HRQL) are increasingly used to evaluate treatment effectiveness in clinical trials, are valued by patients, and may inform important decisions in the clinical setting. It is of concern, therefore, that preliminary…

Also available at: PLOS

Acceptability of donor funding for clinical trials in the UK: a qualitative empirical ethics study using focus groups to elicit the views of research patient public involvement group members, research ethics committee chairs and clinical researchers

Simon Bowman; Heather Draper; Alexander Masters et al.

BMJ Open, Vol. 12 No. 6 · 2022 · English · DOAJ Scopus

Objectives The Plutocratic Proposal is a novel method of funding early phase clinical trials where a single donor funds the entire trial and in so doing secures a place on it. The aim of this study was to identify and explore concerns that may be raised by UK research ethics committees (RECs) when…

Using symbiotic empirical ethics to explore the significance of relationships to clinical ethics: findings from the Reset Ethics research project

Caroline A. B. Redhead; Lucy Frith; Anna Chiumento et al.

BMC Medical Ethics, Vol. 25 No. 1 · 2024 · English · DOAJ Scopus

Abstract Background At the beginning of the coronavirus (Covid-19) pandemic, many non-Covid healthcare services were suspended. In April 2020, the Department of Health in England mandated that non-Covid services should resume, alongside the continuing pandemic response. This ‘resetting’ of…

Which ethical values underpin England’s National Health Service reset of paediatric and maternity services following COVID-19: a rapid review

Paul Baines; Heather Draper; Lucy Frith et al.

BMJ Open, Vol. 11 No. 6 · 2021 · English · DOAJ Scopus

Objective To identify ethical values guiding decision making in resetting non-COVID-19 paediatric surgery and maternity services in the National Health Service (NHS).Design A rapid review of academic and grey literature sources from 29 April to 31 December 2020, covering non-urgent, non-COVID-19…

Correction: Patient Reported Outcomes (PROs) in Clinical Trials: Is ‘In-Trial’ Guidance Lacking? A Systematic Review.

Derek G. Kyte; Heather Draper; Jonathan Ives et al.

PLoS ONE, Vol. 9 No. 1 · 2014 · English · DOAJ Scopus

Also available at: PLOS

Patient reported outcomes (PROs) in clinical trials: is 'in-trial' guidance lacking? a systematic review.

Derek G Kyte; Heather Draper; Jonathan Ives et al.

PLoS ONE, Vol. 8 No. 4 · 2013 · English · DOAJ Scopus

BackgroundPatient reported outcomes (PROs) are increasingly assessed in clinical trials, and guidelines are available to inform the design and reporting of such trials. However, researchers involved in PRO data collection report that specific guidance on 'in-trial' activity (recruitment, data…

Also available at: PLOS

Wilms tumour: Long-term survival of patients treated at Mbingo Baptist Hospital in Cameroon between 2007 and 2012

Peter B. Hesseling; Richard Bardin; James A. Brown et al.

South African Journal of Oncology, Vol. 3 No. 0 · 2019 · English · DOAJ

Background: The survival rate of Wilms tumour (WT) in low-income sub-Saharan countries in Africa is below 50%. Thirty-five consecutive children diagnosed with WT between 2007 and 2012 at Mbingo Baptist Hospital, Cameroon, were observed in this study and treated with a modified International Society…