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38 results for "Ina"

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  1. Journal Article Full text

    The PI3K-Akt-mTOR Signaling Pathway in Human Acute Myeloid Leukemia (AML) Cells

    Ina Nepstad; Kimberley Joanne Hatfield; Ida Sofie Grønningsæter et al.

    International Journal of Molecular Sciences · 2020 · English · OpenAlex Scopus

    Acute myeloid leukemia (AML) is a heterogeneous group of diseases characterized by uncontrolled proliferation of hematopoietic stem cells in the bone marrow. Malignant cell growth is characterized by disruption of normal intracellular signaling, caused by mutations or aberrant external signaling…

  2. Journal Article Full text

    MOF-in-COF molecular sieving membrane for selective hydrogen separation

    Hongwei Fan; Manhua Peng; Ina Strauß et al.

    Nature Communications · 2021 · English · OpenAlex Scopus

    Abstract Covalent organic frameworks (COFs) are promising materials for advanced molecular-separation membranes, but their wide nanometer-sized pores prevent selective gas separation through molecular sieving. Herein, we propose a MOF-in-COF concept for the confined growth of metal-organic…

  3. Book Chapter Full text

    How Big Old Companies Navigate Digital Transformation

    Ina M. Sebastian; Jeanne W. Ross; Cynthia Mathis Beath et al.

    2020 · English · OpenAlex

    New digital technologies present both game-changing opportunities for—and existential threats to—companies whose success was built in the pre-digital economy. This article describes our findings from a study of 25 companies that were embarking on digital transformation journeys. We identified two…

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  1. Journal Article Full text

    Antimicrobial Susceptibility Testing: A Comprehensive Review of Currently Used Methods

    Ina Gajić; Jovana Kabić; Dušan Kekić et al.

    Antibiotics · 2022 · English · OpenAlex Scopus

    Antimicrobial resistance (AMR) has emerged as a major threat to public health globally. Accurate and rapid detection of resistance to antimicrobial drugs, and subsequent appropriate antimicrobial treatment, combined with antimicrobial stewardship, are essential for controlling the emergence and…

  2. Journal Article Full text

    Nature-based solutions in the urban context: terminology, classification and scoring for urban challenges and ecosystem services

    Joana Castellar; Lucía Alexandra Popartan; Josep Pueyo‐Ros et al.

    The Science of The Total Environment · 2021 · English · OpenAlex Scopus

    The concept of Nature-Based Solutions (NBS) has emerged to foster sustainable development by transversally addressing social, economic, and environmental urban challenges. However, there is still a considerable lack of agreement on the conceptualization of NBS, especially concerning typologies…

  3. Journal Article Full text

    Surplus Carbon Drives Allocation and Plant–Soil Interactions

    Cindy E. Prescott; S. J. Grayston; Heljä‐Sisko Helmisaari et al.

    Trends in Ecology & Evolution · 2020 · English · OpenAlex Scopus

    Plant growth is usually constrained by the availability of nutrients, water, or temperature, rather than photosynthetic carbon (C) fixation. Under these conditions leaf growth is curtailed more than C fixation, and the surplus photosynthates are exported from the leaf. In plants limited by nitrogen…

  4. Journal Article Full text

    Sexually Transmitted Infections Treatment Guidelines, 2021

    Kimberly Workowski; Laura H. Bachmann; Philip A. Chan et al.

    MMWR Recommendations and Reports · 2021 · English · OpenAlex Scopus

    These guidelines for the treatment of persons who have or are at risk for sexually transmitted infections (STIs) were updated by CDC after consultation with professionals knowledgeable in the field of STIs who met in Atlanta, Georgia, June 11-14, 2019. The information in this report updates the…

  5. Journal Article Full text

    Beyond Mechanical Recycling: Giving New Life to Plastic Waste

    Ina Vollmer; Michael J. F. Jenks; Mark C. P. Roelands et al.

    Angewandte Chemie International Edition · 2020 · English · OpenAlex Scopus

    Increasing the stream of recycled plastic necessitates an approach beyond the traditional recycling via melting and re-extrusion. Various chemical recycling processes have great potential to enhance recycling rates. In this Review, a summary of the various chemical recycling routes and assessment…

  6. Journal Article Full text

    Efficient overall water splitting in acid with anisotropic metal nanosheets

    Dongshuang Wu; Kohei Kusada; Satoru Yoshioka et al.

    Nature Communications · 2021 · English · OpenAlex Scopus

    Abstract Water is the only available fossil-free source of hydrogen. Splitting water electrochemically is among the most used techniques, however, it accounts for only 4% of global hydrogen production. One of the reasons is the high cost and low performance of catalysts promoting the oxygen…

  7. Journal Article Full text

    Disentangling the mechanisms shaping the surface ocean microbiota

    Ramiro Logares; Ina Maria Deutschmann; Pedro C. Junger et al.

    Microbiome · 2020 · English · OpenAlex Scopus

    BACKGROUND: The ocean microbiota modulates global biogeochemical cycles and changes in its configuration may have large-scale consequences. Yet, the underlying ecological mechanisms structuring it are unclear. Here, we investigate how fundamental ecological mechanisms (selection, dispersal and…

  8. Journal Article Full text

    TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

    Martina Hallegger; Anob M. Chakrabarti; Flora C. Y. Lee et al.

    Cell · 2021 · English · OpenAlex Scopus

    Mutations causing amyotrophic lateral sclerosis (ALS) often affect the condensation properties of RNA-binding proteins (RBPs). However, the role of RBP condensation in the specificity and function of protein-RNA complexes remains unclear. We created a series of TDP-43 C-terminal domain (CTD)…

  9. Journal Article Full text

    Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

    Cordula Stillhart; Katarina M. Vučićević; Patrick Augustijns et al.

    European Journal of Pharmaceutical Sciences · 2020 · English · OpenAlex Scopus

    The release and absorption profile of an oral medication is influenced by the physicochemical properties of the drug and its formulation, as well as by the anatomy and physiology of the gastrointestinal (GI) tract. During drug development the bioavailability of a new drug is typically assessed in…

  10. Journal Article Full text

    The Lancet Global Health Commission on financing primary health care: putting people at the centre

    Kara Hanson; Nouria Brikci; Darius Erlangga et al.

    The Lancet Global Health · 2022 · English · OpenAlex Scopus

    The Lancet Global Health Commissions classified, and reported to enable longitudinal and crosscountry analyses of achievement of key primary healthcare financing goals.(5) Academic researchers, technical experts, and policy makers, among others, should pursue a robust research agenda on financing…

  11. Journal Article Full text

    The fungal collaboration gradient dominates the root economics space in plants

    Joana Bergmann; Alexandra Weigelt; Fons van der Plas et al.

    Science Advances · 2020 · English · OpenAlex Scopus

    Plant economics run on carbon and nutrients instead of money. Leaf strategies aboveground span an economic spectrum from "live fast and die young" to "slow and steady," but the economy defined by root strategies belowground remains unclear. Here, we take a holistic view of the belowground economy…

  12. Journal Article Full text

    RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

    Jordina Guillén‐Boixet; Andrii Kopach; Alex S. Holehouse et al.

    Cell · 2020 · English · OpenAlex Scopus

    Stressed cells shut down translation, release mRNA molecules from polysomes, and form stress granules (SGs) via a network of interactions that involve G3BP. Here we focus on the mechanistic underpinnings of SG assembly. We show that, under non-stress conditions, G3BP adopts a compact auto-inhibited…

  13. Journal Article Full text

    An integrated framework of plant form and function: the belowground perspective

    Alexandra Weigelt; Liesje Mommer; Karl Andraczek et al.

    New Phytologist · 2021 · English · OpenAlex Scopus

    Plant trait variation drives plant function, community composition and ecosystem processes. However, our current understanding of trait variation disproportionately relies on aboveground observations. Here we integrate root traits into the global framework of plant form and function. We developed…

  14. Journal Article Full text

    Feeding habits and multifunctional classification of soil‐associated consumers from protists to vertebrates

    Anton Potapov; Frédéric Beaulieu; Klaus Birkhofer et al.

    Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2022 · English · OpenAlex

    Soil organisms drive major ecosystem functions by mineralising carbon and releasing nutrients during decomposition processes, which supports plant growth, aboveground biodiversity and, ultimately, human nutrition. Soil ecologists often operate with functional groups to infer the effects of…