11 hasil untuk "Jane Ho"

Acute internal medicine as the engine room of the modern hospital: The Midland Metropolitan University Hospital blueprint

Sarbjit Clare, MBE; Jane Ho; Rachel Barlow

Future Healthcare Journal, Vol. 13 No. 2 · 2026 · Inggris · DOAJ Scopus

Modern hospitals are increasingly defined by their ability to manage undifferentiated, complex acute medical demand rather than elective programmes or specialist services. The Midland Metropolitan University Hospital (MMUH) opened in October 2024, and is one of the first major UK acute hospitals…

Psychosocial assessment of adolescents and young adults in paediatric hospital settings: patient and staff perspectives on implementation of the e-HEEADSSS

Daniel Waller; Sophie Bailey; Elham Zolfaghari dkk.

BMC Health Services Research, Vol. 23 No. 1 · 2023 · Inggris · DOAJ Scopus

Abstract Background The main causes of morbidity and mortality for adolescents and young adults are preventable and stem from psychosocial and behavioural concerns. Psychosocial assessments can help clinicians to identify and respond holistically to risks and strengths that may impact upon a young…

Effects of Nutrients and Growth Regulators on Seed Germination and Development of Juvenile Rhizome Proliferation of Gastrodia elata In Vitro

Chi-Hung Hsieh; Zeng-Chin Liang; Wen-Jang Shieh dkk.

Agriculture, Vol. 12 No. 8 · 2022 · Inggris · DOAJ Scopus

Two prevalent issues with Gastrodia elata growing in a natural wild environment are the necessary symbiotic seed germination with Mycena spp. and the long growing cycle of protocorms into mature rhizomes with Armillaria mellea. This study explored the most suitable nutrients to germinate seeds and…

Patient and carer transition outcomes and experiences at the Westmead Centre for Adolescent and Young Adult Health, Westmead, Australia: protocol for a longitudinal cohort study

Yvonne Zurynski; Katharine Steinbeck; Susan Towns dkk.

BMJ Open, Vol. 14 No. 8 · 2024 · Inggris · DOAJ Scopus

Introduction The Westmead Centre for Adolescent and Young Adult Health is a purpose-built facility supporting integrated care for young patients with a variety of long-term health conditions transitioning from paediatric services at the Children’s Hospital at Westmead to adult services at Westmead…

Patient Perceptions of Exertion and Dyspnea With Interleukin-1 Blockade in Patients With Recently Decompensated Systolic Heart Failure

Mihalick, Virginia; Wohlford, George; Talasaz, Azita H dkk.

Am J Cardiol · 2022 · Inggris · PubMed Central

Interleukin-1 (IL-1) blockade is an anti-inflammatory treatment that may affect exercise capacity in heart failure (HF). We evaluated patient-reported perceptions of exertion and dyspnea at sub-maximal exercise during cardiopulmonary exercise testing (CPET) in a double-blind, placebo-controlled…

PARP inhibitor Olaparib overcomes Sorafenib resistance through reshaping the pluripotent transcriptome in hepatocellular carcinoma

Yang, Xiao-Dong; Kong, Fan-En; Qi, Ling dkk.

Mol Cancer · 2021 · Inggris · PubMed Central

Hepatocellular carcinoma (HCC) is one of the most common human malignancies worldwide with very poor prognosis. Resistance to targeted therapeutic drugs such as sorafenib remains one of the major challenges in clinical treatment. In the present study, PARP1 was found to be highly expressed in human…

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Nationwide Newborn Screening Program for Mucopolysaccharidoses in Taiwan and an Update of the “Gold Standard” Criteria Required to Make a Confirmatory Diagnosis

Chih-Kuang Chuang; Chung-Lin Lee; Ru-Yi Tu dkk.

Diagnostics, Vol. 11 No. 9 · 2021 · Inggris · DOAJ Scopus

Mucopolysaccharidoses (MPSs) are a group of lysosomal storage diseases (LSDs) caused by an inherited gene defect. MPS patients can remain undetected unless the initial signs or symptoms have been identified. Newborn screening (NBS) programs for MPSs have been implemented in Taiwan since 2015, and…

Change in Eosinophil Count in Patients with Heart Failure Treated with Anakinra

Michele Golino; Francesco Moroni; Marco Giuseppe Del Buono dkk.

Cells, Vol. 12 No. 8 · 2023 · Inggris · DOAJ Scopus

Background: Interleukin-1 blockade with anakinra leads to a transient increase in eosinophil blood count (eosinophils) in patients with acute myocardial infarction. We aimed to investigate the effect of anakinra on changes in eosinophils in patients with heart failure (HF) and their correlation…

Methylmalonic acidemia/propionic acidemia – the biochemical presentation and comparing the outcome between liver transplantation versus non-liver transplantation groups

Tzu-Hung Chu; Yin-Hsiu Chien; Hsiang-Yu Lin dkk.

Orphanet Journal of Rare Diseases, Vol. 14 No. 1 · 2019 · Inggris · DOAJ Scopus

Abstract Background Most patients with isolated methylmalonic acidemia (MMA) /propionic acidemia (PA) presenting during the neonatal period with acute metabolic distress are at risk for death and significant neurodevelopmental disability. The nationwide newborn screening for MMA/PA has been in…

Precision Medicine to Redefine Insulin Secretion and Monogenic Diabetes-Randomized Controlled Trial (PRISM-RCT) in Chinese patients with young-onset diabetes: design, methods and baseline characteristics

Elaine Cheung; Maggie Wang; Juliana C N Chan dkk.

BMJ Open Diabetes Research & Care, Vol. 12 No. 3 · 2024 · Inggris · DOAJ Scopus

Introduction We designed and implemented a patient-centered, data-driven, holistic care model with evaluation of its impacts on clinical outcomes in patients with young-onset type 2 diabetes (T2D) for which there is a lack of evidence-based practice guidelines.Research design and methods In this…