8 hasil untuk "Kuan-Fu Lin"

The roles of Arabidopsis HSFA2, HSFA4a, and HSFA7a in the heat shock response and cytosolic protein response

Kuan-Fu Lin; Meng-Yu Tsai; Chung-An Lu dkk.

Botanical Studies, Vol. 59 No. 1 · 2018 · Inggris · DOAJ Scopus

Abstract Previously, we found that Arabidopsis plants transformed with a construct containing the promoter of Oshsp17.3 from rice fused to the β-glucuronidase gene (GUS), Oshsp17.3Pro::GUS (Oshsp17.3p), showed a GUS signal after heat shock (HS) or azetidine-2-carboxylic acid (AZC) treatment. HS and…

Specific personality traits and associated psychosocial distresses among individuals with heroin or methamphetamine use disorder in Taiwan

Chia-Hao Ma; Kuan-Fu Lin; Tzu-Ting Chen dkk.

Journal of the Formosan Medical Association, Vol. 119 No. 3 · 2020 · Inggris · DOAJ Scopus

Background/Purpose: Previous studies showed the association between substance use disorders (SUDs) and borderline and antisocial personality disorders. Substance abusers may have emotional, somatic and interpersonal distresses. This study aimed to investigate the associations between substance…

NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius

Chin-Yu Chen; Tzu-Ping Ko; Kuan-Fu Lin dkk.

Scientific Reports, Vol. 8 No. 1 · 2018 · Inggris · DOAJ Scopus

Abstract Ketol-acid reductoisomerase (KARI) is a bifunctional enzyme in the second step of branched-chain amino acids biosynthetic pathway. Most KARIs prefer NADPH as a cofactor. However, KARI with a preference for NADH is desirable in industrial applications including anaerobic fermentation for…

Dual dimeric interactions in the nucleic acid-binding protein Sac10b lead to multiple bridging of double-stranded DNA

Songqiang Tang; Chun-Hsiang Huang; Tzu-Ping Ko dkk.

Heliyon, Vol. 10 No. 11 · 2024 · Inggris · DOAJ Scopus

Nucleoid-associated proteins play a crucial role in the compaction and regulation of genetic material across organisms. The Sac10b family, also known as Alba, comprises widely distributed and highly conserved nucleoid-associated proteins found in archaea. Sac10b is identified as the first 10 kDa…

The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA

Bo-Lin Lin; Chin-Yu Chen; Chun-Hsiang Huang dkk.

PLOS ONE, Vol. 12 No. 1 · 2017 · Inggris · PLOS Scopus

The Sso7c4 from Sulfolobus solfataricus forms a dimer, which is believed to function as a chromosomal protein involved in genomic DNA compaction and gene regulation. Here, we present the crystal structure of wild-type Sso7c4 at a high resolution of 1.63 Å, showing that the two basic C-termini are…

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Simulation study to demonstrate biases created by diagnostic criteria of mental illnesses: major depressive episodes, dysthymia, and manic episodes

Yi-Sheng Chao; Kuan-Fu Lin; Chao-Jung Wu dkk.

BMJ Open, Vol. 10 No. 11 · 2020 · Inggris · DOAJ Scopus

Objectives Composite diagnostic criteria alone are likely to create and introduce biases into diagnoses that subsequently have poor relationships with input symptoms. This study aims to understand the relationships between the diagnoses and the input symptoms, as well as the magnitudes of biases…

The psychological and physiological effects of integrated cognitive-behavioral and biofeedback therapy on panic disorder: A randomized controlled trial

Chia-Hao Ma; Hung-Yeh Chang; Hui-Chun Lee dkk.

Journal of the Formosan Medical Association, Vol. 122 No. 12 · 2023 · Inggris · DOAJ Scopus

Background: Cognitive-behavioral therapy (CBT) and biofeedback therapy are commonly regarded as effective treatment modalities for panic disorder. The aim of this study was to establish a Taiwanese version of an integrated cognitive-behavioral and biofeedback therapy (ICB) and examine its effects…