55 hasil untuk "Laila Rashed"

Salivary expression of lncRNA DQ786243 and IL-17 in oral lichen planus: case–control study

Engy Abdeldayem; Laila Rashed; Shereen Ali

BMC Oral Health, Vol. 22 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background A growing number of studies has investigated IL-17 in OLP. However, its exact role and interactions are not fully determined. In addition, the literature investigating its salivary expression is limited. The scarcity in the literature studying lncRNAs was noticed, particularly…

T-cell markers in systemic lupus erythromatosus patients

Laila Rashed; Randa Talaat; Mostafa Drawy

Research Journal of Applied Biotechnology, Vol. 4 No. 1 · 2018 · Inggris · DOAJ

Systemic lupus erythematosis (SLE) is an autoimmune disease characterized by the presence of multiple autoantibodies. Detecting the expression of CD antigens is supposed to be novel diagnosis methods. Therefore, the aim of current study was to investigate the importance of 2 markers (CD69 and CD73)…

Evaluation of Renal Gene Expression of Protein Kinase C (PKC) Isoforms in Diabetic and Nondiabetic Proliferative Glomerular Diseases

Salwa Ibrahim; Laila Rashed; Sawsan Fadda

The Scientific World Journal, Vol. 8 · 2008 · Inggris · DOAJ Scopus

The protein kinase C (PKC) family consists of 13 members categorized as conventional or novel depending on whether diacylglycerol, calcium, or phosphatidylserine is required for activation. High glucose leads to activation of different forms of PKC across tissue types, thus determining the kind of…

The cross-talk between matrix metalloproteinase-9, RANKL/OPG system and cardiovascular risk factors in ovariectomized rat model of postmenopausal osteoporosis

Maha Sabry; Seham Mostafa; Samaa Kamar dkk.

PLOS ONE, Vol. 16 No. 10 · 2021 · Inggris · PLOS Scopus

Epidemiology and pathogenesis of cardiovascular diseases (CVD) and osteoporosis are strikingly overlapping. This study presents matrix metalloproteinase-9 (MMP-9), as a simple molecular link more consistently associated with the pathophysiology of both osteoporosis and CVD risk factors. 40 adult…

Juga tersedia di: DOAJ

Plasma lactoferrin level as a predictor to endothelial dysfunction in patients with obstructive sleep apnea

Abir Zakaria; Mostafa El Shazly; Laila Rashed

The Egyptian Journal of Internal Medicine, Vol. 25 No. 2 · 2013 · Inggris · DOAJ

Background Obstructive sleep apnea (OSA) syndrome is associated with cardiovascular complications attributed to endothelial dysfunction. There are contradictory reports on whether lactoferrin is protective or injurious to the blood vessels. Objectives To determine circulating plasma lactoferrin…

Matrix metalloproteinase 9 a potential major player connecting atherosclerosis and osteoporosis in high fat diet fed rats

Maha Sabry; Seham Mostafa; Laila Rashed dkk.

PLOS ONE, Vol. 16 No. 2 · 2021 · Inggris · PLOS Scopus

Background: Cardiovascular diseases (CVD) represent one of the major sequelae of obesity. On the other hand, the relationship between bone diseases and obesity remains unclear. An increasing number of biological and epidemiological studies suggest the presence of a link between atherosclerosis and…

Serum Zonulin and Its Role in Rosacea Pathogenesis: A Comprehensive Estimation Study

Fatma Shabaka; Laila Rashed; Mona Ali dkk.

Dermatology Practical & Conceptual, Vol. 15 No. 3 · 2025 · Inggris · DOAJ Scopus

Introduction: Rosacea is a chronic inflammatory skin disorder distinguished by recurrent episodes of inflammatory papules, persistent erythema, facial flushing, pustules, and telangiectasia. Any disturbance in the gut microbiome could influence the immune system equilibrium in rosacea through the…

Circulating

Safy Kaddah; Samah Selim; Laila Rashed dkk.

Egyptian Journal of Chest Disease and Tuberculosis, Vol. 63 No. 4 · 2014 · Inggris · DOAJ

Rationale: Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation that is associated with an enhanced inflammatory response in the airways and the lung. The remodeling process in COPD is greatly under the influence of growth factors. Lung fibroblasts in COPD…

Comparative Study of SIRT1 Expression in Hepatitis B Virus, Hepatitis C Virus, and Hepatocellular Carcinoma Patients

Ahmed Ibrahim; Laila Rashed; Antoun Ghaly dkk.

Egyptian Journal of Medical Research, Vol. 3 No. 2 · 2022 · Inggris · DOAJ

Background and Aim: The most common form of primary liver cancer in adults is hepatocellular carcinoma (HCC), and it is the most common cause of death in people with cirrhosis. The mammalian Sir2 family or sirtuins is formed of a cluster of highly conserved proteins triggering nicotinamide adenine…

Fibroblast Growth Factor 7: Is it Efficient in Detecting Seminal Stains after Long Term Storage?

Iman Gaballah; Ezz Shalaby; Laila Rashed dkk.

The Egyptian Journal of Forensic Sciences and Applied Toxicology, Vol. 20 No. 2 · 2020 · Inggris · DOAJ

ABSTRACT INTRODUCTION: proper detection and analysis of the biological evidence is a crucial matter for crime scene reconstruction and the most promising method for tissue determination is the analysis of differential DNA methylation patterns according to cell or tissue type. These patterns are…

Evaluation of ascitic lactoferrin as a diagnostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis

Walid Abdelrehim; Ayman Fouad; Laila Rashed dkk.

The Egyptian Journal of Internal Medicine, Vol. 37 No. 1 · 2025 · Inggris · DOAJ

Abstract Background The optimal cut-off level of lactoferrin in ascitic fluid is debatable for identification of spontaneous bacterial peritonitis (SBP). This study aimed to detect the cut-off level of lactoferrin in ascitic fluid and its role in the diagnosis of SBP in patients with liver…

Association of Angiotensin-Converting Enzyme (ACE) Gene Polymorphism with Inflammation and Cellular Cytotoxicity in Vitiligo Patients

Laila Rashed; Rania Abdel Hay; Rania Mahmoud dkk.

PLOS ONE, Vol. 10 No. 7 · 2015 · Inggris · PLOS Scopus

Background: Vitiligo is a disorder with profound heterogeneity in its aetio-pathophysiology. Angiotensin converting enzyme (ACE) plays an important role in the physiology of the vasculature, blood pressure and inflammation. An insertion/deletion (I/D) polymorphism of the ACE gene was reported be…

Dipeptidyl peptidase‐4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats

Nagat Younan; Samah Elattar; Mira Farouk dkk.

Physiological Reports, Vol. 7 No. 17 · 2019 · Inggris · DOAJ Scopus

Abstract Menopause increases the risk of non‐alcoholic fatty liver disease (NAFLD). We investigated the effect of incretin and/ or exercise on the hepatic fat accumulation in ovariectomized rats. Rats were divided into five groups: Group 1: Control rats, Group 2: Ovariectomized rats, Group 3…

Vanin-1 Gene Expression in Acne Vulgaris and its Correlation with Disease Severity

Aya Amin; Abd-ElAziz El-Rifaie; Laila Rashed dkk.

Egyptian Journal of Medical Research, Vol. 1 No. 2 · 2020 · Inggris · DOAJ

Background: Acne vulgaris is the most prevalent chronic disease worldwide, occurs during adolescence. The pathogenesis is multifactorial with different grades of severity and the human vanin gene family especially vanin-1 might play a role in pathogenesis of acne. Aim: explore the role of Vanin-1…

Correlation of Vitamin D and Vitamin D Receptors in Chronic Telogen Effluvium in Females

Asmaa Rashad; Laila Rashed; Yasser Gohary dkk.

Minia Journal of Medical Research, Vol. 31 No. 2 · 2020 · Inggris · DOAJ

Telogen effluvium (TE) is the most common form of hair loss. It is caused by any disruption of hair growth cycle resulting in increased synchronized telogen hair shedding. This study was conducted to correlate of vitamin D and vitamin D receptor in chronic telogen effluvium in females.The study…

Proprotein convertase subtilisin/kexin 9 (PCSK9) in patients with diffuse systemic sclerosis: A marker of disease activity and severe disease manifestations with potential therapeutic implementations

Joy Artin; Yumn A. Elsabagh; Laila Rashed dkk.

The Turkish Journal of Gastroenterology, Vol. 38 No. 2 · 2023 · Inggris · DOAJ Scopus

Objectives: This study aims to investigate proprotein convertase subtilisin/kexin 9 (PCSK9) in patients with diffuse systemic sclerosis (d-SSc) and its relation to disease activity, severity and subclinical atherosclerosis in such group of patients. Patients and methods: Between December 2019 and…

Role of active vitamin D in protection against glucocorticoids induced metabolic syndrome and gastric lesion

Akef Khowailed; Ahmed Naeem; Enas Rateb dkk.

Zagazig University Medical Journal, Vol. 29 No. 3 · 2023 · Inggris · DOAJ

Background: Glucocorticoids are used in the treatment of several diseases, but they have many side effects. many actions for vitamin D have been discovered due to its strong antioxidant properties. Objective: The aim of the present study was to detect the protective effect of vitamin D against…

Detection of Desmoglein-3 Auto-Antibodies in Patients with Lichen Planus

Abd-El Aziz El-Rifaie; Laila Rashed; Mona Abdellatif dkk.

Egyptian Journal of Medical Research, Vol. 3 No. 3 · 2022 · Inggris · DOAJ

There is controversy about the role of auto anti-bodies against desmoglein 3 (Dsg 3) in the pathogenesis of lichen planus (LP). The goal of this study is to detect desmoglein-3 auto-antibodies in lichen planus patients comparted to normal control persons via investigating its potential role in the…

Detection of Cyclophilin D in Psoriasis and its Correlation with Disease Severity

Sara Abd-ElAzim; Abd-ElAziz El-Rifaie; Laila Rashed dkk.

Egyptian Journal of Medical Research, Vol. 3 No. 1 · 2022 · Inggris · DOAJ

The aim of the work to detect the level of Cyclophilin-D in psoriasis and its correlation with disease severity. Samples included 84 persons divided into 2 groups (42) patients having psoriasis and (42) apparently healthy age and sex-matched individuals. All individuals included in the study were…