40 hasil untuk "Li-Teh Liu"

Comparative outcomes of COVID-19 in patients with primary Sjögren’s syndrome treated with hydroxychloroquine versus methotrexate: a retrospective cohort study

Jih-Jin Tsai; Li-Teh Liu; Pei-Lun Liao dkk.

Annals of Medicine, Vol. 57 No. 1 · 2025 · Inggris · DOAJ Scopus

Background People with rheumatic diseases are considered at risk for severe coronavirus disease 2019 (COVID-19) because of their underlying abnormal immune responses and frequent disease-modifying antirheumatic drug (DMARD) use. We aimed to explore COVID-19 outcomes in patients with primary…

Low frequency of asymptomatic dengue virus-infected donors in blood donor centers during the largest dengue outbreak in Taiwan

Jih-Jin Tsai; Ping-Chang Lin; Ching-Yi Tsai dkk.

PLOS ONE, Vol. 13 No. 10 · 2018 · Inggris · PLOS Scopus

To determine the prevalence of asymptomatic dengue virus-infected blood donors during the largest dengue outbreak in Taiwan history occurred in 2015, we examined the evidence of dengue virus (DENV) infection by the detection of DENV RNA genome using real-time reverse transcription-polymerase chain…

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Spatiotemporal Dynamics and Epistatic Interaction Sites in Dengue Virus Type 1: A Comprehensive Sequence-Based Analysis

Pei-Yu Chu; Guan-Ming Ke; Po-Chih Chen dkk.

PLoS ONE, Vol. 8 No. 9 · 2013 · Inggris · PLOS Scopus

The continuing threat of dengue fever necessitates a comprehensive characterisation of its epidemiological trends. Phylogenetic and recombination events were reconstructed based on 100 worldwide dengue virus (DENV) type 1 genome sequences with an outgroup (prototypes of DENV2-4). The phylodynamic…

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Comparison of two rapid diagnostic tests during a large dengue virus serotype 3 outbreak in the Solomon Islands in 2013

Li-Teh Liu; Tenneth Dalipanda; Rooney Jagilly dkk.

PLOS ONE, Vol. 13 No. 8 · 2018 · Inggris · PLOS Scopus

Dengue virus (DENV) infection causes various clinical presentations, including asymptomatic infection, dengue with or without warning signs and severe dengue. An early and accurate diagnosis of DENV infection during the first few days of illness supports clinical management and significantly…

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COVID-19 outcomes in patients with rheumatoid arthritis with biologic or targeted synthetic DMARDs

James Cheng-Chung Wei; Jih-Jin Tsai; Li-Teh Liu dkk.

RMD Open, Vol. 9 No. 3 · 2023 · Inggris · DOAJ Scopus

Objectives We aimed to investigate the role of rheumatoid arthritis (RA) with biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARD) exposure in COVID-19 outcomes.Methods Our study retrieved data from the US Collaborative Network in TriNetX between 1 January 2018 and 31…

Seroprevalence of dengue virus in two districts of Kaohsiung City after the largest dengue outbreak in Taiwan since World War II

Jih-Jin Tsai; Ching-Kuan Liu; Wen-Yang Tsai dkk.

PLOS Neglected Tropical Diseases, Vol. 12 No. 10 · 2018 · Inggris · PLOS Scopus

Dengue virus (DENV) is the leading cause of arboviral diseases in humans worldwide. In this study, we investigated the seroprevalence of DENV infection in two districts of Kaohsiung City, a metropolis in southern Taiwan, where major dengue outbreaks have occurred in the past three decades. We…

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Evaluation of rapid diagnostic tests to detect dengue virus infections in Taiwan

Li-Teh Liu; Chun-Hong Chen; Ching-Yi Tsai dkk.

PLOS ONE, Vol. 15 No. 9 · 2020 · Inggris · PLOS Scopus

Early diagnosis is important for the clinical management of diseases caused by dengue virus (DENV) infections. We investigated the performance of three commercially available DENV nonstructural protein 1 (NS1) rapid diagnostic tests (RDTs) using 173 acute-phase sera collected from dengue…

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Case Report: An endogenous endophthalmitis case caused by Haemophilus influenzae

Chia Hsuan Tsai; Li-Teh Liu; En Chi Hsu dkk.

Frontiers in Medicine, Vol. 12 · 2025 · Inggris · DOAJ Scopus

Haemophilus influenzae is a bacterium that typically colonizes the human respiratory tract. However, it can also infect the eyes, potentially leading to endophthalmitis. The general prognosis of endophthalmitis is often poor, frequently resulting in decreased visual acuity. We present the case of a…

Case Report: Expanded dengue syndrome with acute pancreatitis and pericardial effusion in octogenarians, from recovery to fatal shock

Chen-Hsuan Lin; Li-Teh Liu; How-Chen Wang dkk.

Frontiers in Medicine, Vol. 13 · 2026 · Inggris · DOAJ Scopus

Severe dengue fever (DF) can involve multiple organs, yet acute pancreatitis (AP) and pericardial effusion remain rare and easily overlooked, particularly in elderly patients who often present atypically. This report describes two women in their eighties who developed both complications…

The epidemiology and identification of risk factors associated with severe dengue during the 2023 dengue outbreak in Kaohsiung City, Taiwan

Li-Teh Liu; Shi-Ya Huang; Chen-Hsuan Lin dkk.

Travel Medicine and Infectious Disease, Vol. 65 · 2025 · Inggris · DOAJ Scopus

After the previous major dengue fever (DF) outbreaks in 2014 and 2015 in Taiwan, the second-largest DF outbreak re-emerged in 2023. A total of 178 patients with laboratory-confirmed dengue virus (DENV) infection, including 92 DENV-1 and 86 DENV-2 cases, were enrolled in this study conducted during…

Defining the clinical utility of dengue RT-iiPCR: stratification by days post-onset and primary vs. secondary infection during the 2023 Taiwan outbreak

Li-Teh Liu; Po-Chih Chen; Ping-Chang Lin dkk.

Travel Medicine and Infectious Disease, Vol. 69 · 2026 · Inggris · DOAJ Scopus

Background: Rapid molecular diagnostics are critical for timely dengue virus (DENV) detection, especially in resource-limited settings. Reverse transcription-insulated isothermal polymerase chain reaction (RT-iiPCR) enables sample-to-answer amplification without thermocyclers. While this platform…

Evaluation of a new NS1 rapid diagnostic test using a single acute‐phase serum panel collected during the largest dengue outbreak in Taiwan history in 2015

Li‐Teh Liu; Chun‐Hong Chen; Ping‐Chang Lin dkk.

Kaohsiung Journal of Medical Sciences, Vol. 38 No. 4 · 2022 · Inggris · DOAJ Scopus

Abstract Dengue virus (DENV) infection results mostly from the bites of virus‐carrying Aedes mosquitoes, which results in dengue fever (DF) with or without warning signs, severe dengue, or asymptomatic infections in humans. For point‐of care identification of DENV‐infected patients, a rapid…

Performance comparison of two dengue NS1 rapid diagnostic tests against RT-PCR: Sensitivity and specificity across infections and timeframes

Li-Teh Liu; Po-Chih Chen; Chen-Hsuan Lin dkk.

Journal of Infection and Public Health, Vol. 18 No. 11 · 2025 · Inggris · DOAJ Scopus

Background: Dengue virus (DENV) is a mosquito-borne flavivirus that remains a global public health threat, particularly in tropical regions where it is endemic. Accurate and timely diagnosis is critical for optimal patient care and effective outbreak containment. While reverse…

Diagnostic performance of a field-deployable iiPCR platform and viral load dynamics of MPXV Clade IIb in a cohort with high prevalence of HIV

Li-Teh Liu; Chao-Ju Chen; Ping-Chang Lin dkk.

Annals of Medicine, Vol. 58 No. 1 · 2026 · Inggris · DOAJ Scopus

Background Since 2022, the global outbreak of Mpox caused by the Mpox virus (MPXV) Clade IIb has underscored the need for timely and decentralized molecular diagnostics. Although quantitative real-time PCR (qPCR) remains the diagnostic gold standard, its infrastructure requirements may limit…