20 hasil untuk "Li-Yan Dong"
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RBBP4 promotes colon cancer malignant progression via regulating Wnt/β-catenin pathway
BACKGROUND: Our previous study demonstrated that RBBP4 was upregulated in colon cancer and correlated with poor prognosis of colon cancer and hepatic metastasis. However, the potential biological function of RBBP4 in colon cancer is still unknown. AIM: To investigate the biological role and the…
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LHPE-nets: A lightweight 2D and 3D human pose estimation model with well-structural deep networks and multi-view pose sample simplification method
The cross-view 3D human pose estimation model has made significant progress, it better completed the task of human joint positioning and skeleton modeling in 3D through multi-view fusion method. The multi-view 2D pose estimation part of this model is very important, but its training cost is also…
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Correlation between invasive microbiota in margin-surrounding mucosa and anastomotic healing in patients with colorectal cancer
BACKGROUND: Impaired anastomotic healing is one of the major complications resulting from radical resection in colorectal cancer (CRC). Accumulating evidence suggests that intestinal microbiota is correlated with anastomotic healing. AIM: To explore the microbiota structural shift in…
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Authors’ Reply to Letter to the Editor “Comparing Sedation Regimens for Awake Fiberoptic Intubation”
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Enterostomy can decrease the mortality of patients with Fournier gangrene
AIM: To determine the significance of enterostomy in the emergency management of Fournier gangrene. METHODS: The clinical data of 51 patients (49 men and 2 women) with Fournier gangrene who were treated at our hospital over the past 12 years were retrospectively analyzed. The patients were divided…
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Excisional hemorrhoidal surgery and its effect on anal continence
AIM: To investigate the role of anal cushions in hemorrhoidectomy and its effect on anal continence of the patients. METHODS: Seventy-six consecutive patients (33 men and 43 women) with a mean age of 44 years were included. They underwent Milligan-Morgan hemorrhoidectomy because of symptomatic…
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Application of 4% formaldehyde under electronic colonoscope as a minimally invasive treatment of chronic hemorrhagic radiation proctitis
BACKGROUND: To investigate the effectiveness of topical application of 4% formaldehyde as a minimally invasive treatment of rectal bleeding due to chronic radiation proctitis (CRP) under direct vision of electronic colonoscope. METHODS: The clinical data of 13 CRP patients complicated with ≥ grade…
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Dexmedetomidine-midazolam versus Sufentanil-midazolam for Awake Fiberoptic Nasotracheal Intubation: A Randomized Double-blind Study
BACKGROUND: Awake fiberoptic intubation (AFOI) is usually performed in the management of the predicted difficult airway. The aim of this study was to evaluate the feasibility of dexmedetomidine with midazolam (DM) and sufentanil with midazolam (SM) for sedation for awake fiberoptic nasotracheal…
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Correlation between different levels of Her-2 protein expression and the efficacy of neoadjuvant therapy in Her-2 positive breast cancer
INTRODUCTION: The purpose of this study was to explore the correlation between the difference of Her-2 protein expression level in Her-2 positive breast cancer and the efficacy of neoadjuvant chemotherapy, so as to determine the best population for neoadjuvant treatment of Her-2 positive breast…
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Lentinan dose dependence between immunoprophylaxis and promotion of the murine liver cancer
Lentinan could exhibit significant biological activity favorable for human health and disease control such as the recovery of patients with liver cancer. In order to investigate the effect of lentinan dose dependence between immunoprophylaxis and promotion of cancer cell proliferation of the murine…
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Changes in gut microbiota composition and diversity associated with post-cholecystectomy diarrhea
BACKGROUND: Post-cholecystectomy diarrhea (PCD) frequently occurs in patients following gallbladder removal. PCD is part of the post-cholecystectomy (PC) syndrome, and is difficult to treat. After cholecystectomy, bile enters the duodenum directly, independent of the timing of meals. The…
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GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit
AIM: To investigate the function of gamma-aminobutyric acid (GABA) and gamma-aminobutyric acid A receptor θ subunit (GABRQ) in hepatocellular carcinoma (HCC). METHODS: Semiquantitative polymerase chain reaction was used for detecting the expression of GABRQ receptor among HCC cell line HepG2…
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High-energy traumatic spondyloptosis at T8–T9 with complete spinal cord injury: a case report
INTRODUCTION: Spondyloptosis, the most severe form of spondylolisthesis, involves complete (>100%) anterior or posterior displacement of one vertebra over the subjacent segment, resulting in total anatomical dislocation. Typically caused by high-energy trauma, it leads to severe spinal instability…
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Synergistic mediating effect of edible fungal polysaccharides (Auricularia and Tremellan) and Crataegus flavonoids in hyperlipidemic rats
Both edible fungal polysaccharides (Auricularia and Tremellan) and Crataegus flavonoids promote the balance of dyslipidemia, which have a positive biological regulating effect on intestinal flora. In this study, the extraction of water‐soluble polysaccharides from Auricularia and Tremellan was…
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The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes
BACKGROUND: The programmed cell death ligand 1 (PD-L1) plays a key role in glioma development. However, due to the specificity of glioma’s anatomical position, the role of its expression as a tumor biomarker is limited. It has been proven that the levels of soluble programmed death-ligand 1…
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Epstein-barr virus super-infection is associated with increased severity of hemorrhagic fever with renal syndrome
Abstract Background This study aimed to characterize the clinical impact of Epstein-Barr virus (EBV) super-infection in patients with Hemorrhagic Fever with Renal Syndrome (HFRS). Methods A cohort of 126 confirmed HFRS patients were enrolled and stratified into EBV (n = 62) and Non-EBV (n = 64)…
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NG2 glia regulate brain innate immunity via TGF-β2/TGFBR2 axis
BACKGROUND: Brain innate immunity is vital for maintaining normal brain functions. Immune homeostatic imbalances play pivotal roles in the pathogenesis of neurological diseases including Parkinson’s disease (PD). However, the molecular and cellular mechanisms underlying the regulation of brain…
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Genotype and mutation patterns of macrolide resistance genes of Mycoplasma pneumoniae from children with pneumonia in Qingdao, China, in 2019
ABSTRACT: Objectives: This study assessed the incidence and resistance of Mycoplasma pneumoniae (MP) in children in Qingdao, China, in 2019. Methods: We detected MP infection in 78 pharyngeal swabs from children with pneumonia by qPCR. The RepMP4 element in the P1 adhesin gene, domain V of the 23S…