134 results for "Linlin Sun"
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Journal Article
Nontyphoidal Salmonella septic arthritis in an elderly man: A case report
Nontyphoidal Salmonella septic arthritis is an uncommon complication of NTS bacteremia in adults. A 75-year-old patient was admitted for right hip pain, presenting with manifestations of septic shock. Following a series of examinations, the patient was diagnosed with nontyphoidal Salmonella septic…
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Journal Article
A mushroom diet reduced the risk of pregnancy-induced hypertension and macrosomia: a randomized clinical trial
Background: Pregnancy-induced hypertension (PIH) is a disease characterized by high blood pressure detected after 20 weeks of pregnancy, affecting approximately 10% of pregnant women worldwide. Effective strategies are imperatively needed to prevent and treat PIH. Methods: Subjects were required to…
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FFT-Based Methods for Computational Contact Mechanics
Computational contact mechanics seeks for numerical solutions to contact area, pressure, deformation, and stresses, as well as flash temperature, in response to the interaction of two bodies. The materials of the bodies may be homogeneous or inhomogeneous, isotropic or anisotropic, layered or…
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Spared Nerve Injury Model of Neuropathic Pain in Mice
Experimental models of peripheral nerve injury have been developed to study mechanisms of neuropathic pain in living animals. The spared nerve injury (SNI) model in rodents is a partial denervation model, in which the common peroneal and tibial nerves are injured, producing consistent and…
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Comparison of pregnancy outcomes and physical conditions of infants in patients with gestational diabetes mellitus treated with metformin and insulin: a meta-analysis study
Abstract Background Gestational diabetes mellitus (GDM) is a common complication during pregnancy, which seriously affects the health of mothers and infants. Metformin and insulin are both commonly used therapeutic drugs, but the effects of the two on pregnancy outcomes and the physical condition…
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Study on Fertility Identification of Monogerm Binary Male-Sterile Lines in Sugar Beet (Beta vulgaris L.) Using Molecular Markers
Sugar beet (Beta vulgaris L.) is one of the most important sugar crops and potential energy crops in China. The utilization of its heterosis is crucial for breaking through the bottlenecks in yield and quality, while the fertility identification of binary male-sterile lines is the core link to…
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Journal Article
Exosomes derived from hTERT-immortalized cells delay cellular senescence of human fibroblasts
hTERT gene therapies hold significant promise for treating age-related diseases. However, further research is required to address the challenges of delivery and ethical considerations. We hypothesized that exosomes derived from hTERT-immortalized cells could function similarly to hTERT gene…
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2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells
Tumor cells rely on aerobic glycolysis to generate ATP, namely the "Warburg" effect. 2-deoxyglucose (2-DG) is well characterized as a glycolytic inhibitor, but its effect on cellular signaling pathways has not been fully elucidated. Herein, we sought to investigate the effect of 2-DG on ERK…
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Exploring the resistance mechanism of triple-negative breast cancer to paclitaxel through the scRNA-seq analysis
Background: The triple negative breast cancer (TNBC) is the most malignant subtype of breast cancer with high aggressiveness. Although paclitaxel-based chemotherapy scenario present the mainstay in TNBC treatment, paclitaxel resistance is still a striking obstacle for cancer cure. So it is…
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Resilience factors and mechanisms in the coal power supply chain: A quantitative analysis using fuzzy DEMATEL, ISM, and ANP methods
Under the influence of global energy market fluctuations, policy changes, and natural disasters, the coal power supply chain faces significant risks. However, existing research on supply chain resilience management, particularly regarding the identification and quantitative analysis of resilience…
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Gait Analysis for Post-Stroke Hemiparetic Patient by Multi-Features Fusion Method
Walking is a basic requirement for participating in daily activities. Neurological diseases such as stroke can significantly affect one’s gait and thereby restrict one’s activities that are a part of daily living. Previous studies have demonstrated that gait temporal parameters are useful for…
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Journal Article
Vancomycin-resistant Enterococcus faecium pneumonia in a uremic patient on hemodialysis: a case report and review of the literature
Abstract Background Even though enterococci can cause serious infections in multiple sites, they are a rare cause of pneumonia. We reported a uremic patient with vancomycin-resistant E. faecium (VRE-fm) pneumonia, possibly related to epileptic seizures. Case presentation A 57-year old man with…
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Journal Article
Analysis of fluid–solid coupling characteristics of tripod sliding universal coupling based on cavitation and thermal effects
In this article, a fluid–solid coupling analysis of tripod sliding universal coupling and lubricating oil film was conducted by taking into consideration cavitation and thermal effects. The coupling of the sleeve and slip pin with the lubricant oil film under different pressure differences and…
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Journal Article
In situ nanoindentation method for characterizing tensile properties of AISI 1045 steel based on mesomechanical analysis
A novel method for characterizing the tensile properties of AISI 1045 steel is proposed by combining the method of in situ nanoindentation test and the theory of mesomechanical analysis. First, the load–depth curves of exact location of ferrite, pearlite and grain boundary on the surface of AISI…
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Journal Article
ATP2C2–PLA2R1 axis underlies lipid metabolism modulation and invasion in papillary thyroid carcinoma mediated by a VGIC signature
Abstract Objective Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with rising incidence globally. Current prognostic markers often lack precision for individualized management. This study develops a prognostic signature based on voltage-gated ion channel (VGIC) genes and…
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Numerical Investigation of Elastic Layer Effects in Wheel–Rail Rolling Contact
In railway systems, layered structures could be induced in wheel–rail contact interfaces due to several causes, such as head hardening, work hardening, plastic deformation, and mechanical or thermal excursion-induced phase transformation. This study proposes an explicit finite element (FE) method…
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An Indirect Method for Accurate Identification of Short-Pitch Rail Corrugation Using Vehicle Interior Noise and Vibration Measurements and Train–Track Transfer Functions
Short-pitch rail corrugation is commonly found at curves or resilient track structures of the metro system, causing fatigue failure of key components of the train–track system. Currently, rail corrugation is detected via routine inspections during the possession period, with the compromise between…
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Pyrroloquinoline-Quinone Suppresses Liver Fibrogenesis in Mice
Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injuries, and its progression toward cirrhosis is the major cause of liver-related morbidity and mortality worldwide. However, anti-fibrotic treatment remains an unconquered area for drug development…
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The Impacts of Random Distributed Vacancy Defects in Steady-State Thermal Conduction of Graphene
The unavoidable vacancy defects dispersed throughout the entire pristine graphene tailor to the integrity of the lattice structure and thereby have complicated impacts on the mechanical and thermal properties of graphene. In order to analyze the influence of vacancy defects on the extraordinary…