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4 results for "Longjun Yan"

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  1. Journal Article

    Accuracy Assessment of Cone-Beam CT Images for Pelvic Tumor Dose Calculation

    Bao LI; Yongzhong CHEN; Jun JIN et al.

    Zhongguo yiliao qixie zazhi, Vol. 49 No. 3 · 2025 · Chinese · DOAJ Scopus

    ObjectiveTo evaluate the feasibility and accuracy of cone-beam CT (CBCT) images for radiotherapy dose calculation in pelvic tumors. MethodsAn improved volumetric density coverage method was used to establish CT value-relative electron density (RED) curves for CBCT images. The planning CT plans were…

  2. Journal Article

    The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro

    Jing Li; Jingjing Yu; Wenxian Xue et al.

    BMC Biotechnology, Vol. 21 No. 1 · 2021 · English · DOAJ Scopus

    Abstract Background HSPB5 is an ATP-independent molecular chaperone that is induced by heat shock or other proteotoxic stresses. HSPB5 is cytoprotective against stress both intracellularly and extracellularly. It acts as a potential therapeutic candidate in ischemia-reperfusion and…

  3. Journal Article

    Biotin attenuates heat shock factor 4b transcriptional activity by lysine 444 biotinylation

    Longjun Yan; Jing Li; Jialin Hu et al.

    Biochemistry and Biophysics Reports, Vol. 30 · 2022 · English · DOAJ Scopus

    Genetic mutations in HSF4 cause congenital cataracts. HSF4 exhibits both positive and negative regulation on the transcription of heat shock and non-heat shock proteins during lens development, and its activity is regulated by posttranslational modifications. Biotin is an essential vitamin that…