4 results for "Longjun Yan"
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Journal Article
Accuracy Assessment of Cone-Beam CT Images for Pelvic Tumor Dose Calculation
ObjectiveTo evaluate the feasibility and accuracy of cone-beam CT (CBCT) images for radiotherapy dose calculation in pelvic tumors. MethodsAn improved volumetric density coverage method was used to establish CT value-relative electron density (RED) curves for CBCT images. The planning CT plans were…
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Journal Article
The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro
Abstract Background HSPB5 is an ATP-independent molecular chaperone that is induced by heat shock or other proteotoxic stresses. HSPB5 is cytoprotective against stress both intracellularly and extracellularly. It acts as a potential therapeutic candidate in ischemia-reperfusion and…
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Journal Article
Biotin attenuates heat shock factor 4b transcriptional activity by lysine 444 biotinylation
Genetic mutations in HSF4 cause congenital cataracts. HSF4 exhibits both positive and negative regulation on the transcription of heat shock and non-heat shock proteins during lens development, and its activity is regulated by posttranslational modifications. Biotin is an essential vitamin that…