146 results for "Lu, Fu"
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Induction of pancreatic duct cells of neonatal rats into insulin-producing cells with fetal bovine serum: A natural protocol and its use for patch clamp experiments
AIM: To induce the pancreatic duct cells into endocrine cells with a new natural protocol for electrophysiological study. METHODS: The pancreatic duct cells of neonatal rats were isolated, cultured and induced into endocrine cells with 15% fetal bovine serum for a period of 20 d. During this…
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Biopolymer Green Lubricant for Sustainable Manufacturing
We report on the preparation of a biopolymer thin film by hydroxypropyl methylcellulose (HPMC), which can be used as a dry green lubricant in sustainable manufacturing. The thin films were characterized through scanning electron microscopy, energy-dispersive spectroscopy, and Raman spectroscopy…
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Sustainability competencies in the workplaces: A systematic review
In past decades, a growing body of research has identified sustainability competencies as a pivotal element in the process of sustainability transition. However, the topic is mainly discussed in the educational field, and few studies have investigated it in the workplaces. The aim of this study is…
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Cancer degronopathies and protein-fate biomarkers in drug resistance and cancer progression: signalling mechanisms, measurement and translational limits
Drug resistance remains a major barrier to durable targeted therapy, and cancer progression often reflects rewiring of signalling pathways that control protein stability. Dysregulation of the ubiquitin–proteasome system, including failure of degron-dependent substrate recognition, can stabilise…
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Identification and mechanism of regulation of the zebrafish dorsal determinant
In vertebrates, the animal–vegetal axis is determined during oogenesis and at ovulation, the egg is radially symmetric. In anamniotes, following fertilization, a microtubule-dependent movement leads to the displacement of maternal dorsal determinants from the vegetal pole to the future dorsal side…
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SGPP2 Ameliorates Chronic Heart Failure by Attenuating ERS via the SIRT1/AMPK Pathway
Objective: To investigate the mechanism by which sphingosine-1-phosphatase 2 (SGPP2) modulates endoplasmic reticulum stress (ERS) through the SIRT1/AMPK pathway to improve ischemic cardiomyopathy-induced chronic heart failure (IHF). Methods: Key genes of IHF and ERS were identified through…
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Extraction and Analysis of Conducted Electromagnetic Susceptibility Elements of Integrated Circuits
A new experimental research method on the electromagnetic susceptibility of integrated circuits (ICs) is proposed in this paper. This method is a new research topic based on seeking basic laws of chip electromagnetic susceptibility, aiming at providing an effective reference for chip…
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Kaempferol Mitigates Pseudomonas aeruginosa-Induced Acute Lung Inflammation Through Suppressing GSK3β/JNK/c-Jun Signaling Pathway and NF-κB Activation
Background: Pseudomonas aeruginosa, one of the common bacterial pathogens causing nosocomial pneumonia, is characterized as highly pathogenic and multidrug-resistant. Kaempferol (KP), a natural flavonoid, has been shown to exhibit effectiveness in treating infection-induced lung injury. Methods: We…
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Secure control plane for SDN using Bayesian Stackelberg games
A dynamic scheduling controller in SDN control layer was proposed by dynamically transform heteroge-neous controlled in order to increase the difficulty of the attacker.Firstly,a dynamic scheduling method based on Bayesian Stackelberg games the attacker and defender were game participation on both…
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Healthcare-associated infections in Chinese neonates: a multicenter retrospective period prevalence survey in Jiangsu Province (2023)
Abstract Background Healthcare-associated infections (HAI) pose a significant threat to neonates, especially preterm and critically ill infants, leading to prolonged hospitalization, increased healthcare costs, and elevated mortality. Understanding the epidemiological characteristics of neonatal…
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Synthesis of temperature-sensitive boron, nitrogen and sulphur doped carbon dots and their applications
Boron-Sulfur-Nitrogen doped carbon dots (B, N, S-CDs) were prepared by a simple hydrothermal method using 2-Mercaptopyrimidine (C4H4N2S) and citric acid (C6H8N7•H2O) as raw materials. The B, N, S-CDs showed exceptional fluorescence response to Fe2+, TC. The results of the B, N, S-CDs are very…
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New 11-Methoxymethylgermacranolides from the Whole Plant of Carpesium divaricatum
Eight new 11-methoxymethylgermacranolides (1–8) were isolated from the ethanol extract of the whole plant of Carpesium divaricatum. The planar structures and relative configurations of the new compounds were determined by detailed spectroscopic analysis. The absolute configuration of 1 was…
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Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells
AIM: Endoplasmic reticulum (ER) stress plays an important role in the pathogenesis of insulin resistance and pancreatic β-cell dysfunction. The aim of this study is to investigate whether the insulin-sensitizing action of berberine is related to reducing ER stress. METHODS: ER stress in cultured…
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Causal relationships between immune cells, inflammatory cytokines, and pertussis: Bidirectional 2-sample Mendelian randomization study and mediation analysis
Studies have shown that immune cells play an important role in the occurrence and development of pertussis, but the specific causal relationships are yet to be determined. Additionally, inflammatory cytokines, as regulators of immune responses, may mediate the relationship between immune cells and…
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Cold atmospheric plasma stabilizes mismatch repair for effective, uniform treatment of diverse colorectal cancer cell types
Mismatch Repair (MMR) mechanisms play a pivotal role in rectifying DNA replication errors and maintaining the stability of DNA microsatellite structure. Colorectal cancer (CRC) can be characterized into microsatellite stability (MSS) and microsatellite instability (MSI) subtypes based on the…
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Long non-coding RNA NEAT1 promotes pulmonary fibrosis by regulating the microRNA-455-3p/SMAD3 axis
Pulmonary fibrosis is an excessive repair response to tissue damage, triggering hyperplasia of fibrotic connective tissues; however, there is no effective treatment in a clinical setting. The purpose of the present study was to investigate the roles of long non-coding RNA nuclear enriched abundant…
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Quantitative Evaluation of Optical Clearing Agent Performance Based on Multilayer Monte Carlo and Diffusion Modeling
Optical clearing agents (OCAs) offer a promising approach to enhance skin transparency by reducing scattering and improving photon transmission, which is critical for non-invasive optical diagnostics such as glucose sensing and vascular imaging. However, the complex multilayered structure of skin…
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Real-world efficacy of comprehensive measures against mother-to-child transmission of HBV in south-eastern Jiangsu, China
Abstract Background Reducing mother-to-child transmission (MTCT) is the crucial step towards eliminating hepatitis B virus (HBV) infection. The aim of this study is to evaluate the efficiency of intervention programme to MTCT of HBV in China and establish a foundation for future clinical practice…
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Capsules Based Chinese Word Segmentation for Ancient Chinese Medical Books
Neural network models are popularly used in Chinese word segmentation task. The capsule architecture is proposed recently which has solved some defects of convolutional neural network. In this paper, we first introduce the capsule architecture to Chinese word segmentation. We utilize capsules as…