2 hasil untuk "Mathumathi Manoharan"
Menampilkan 1–2 · 0,34 detik · RSS
-
Artikel Jurnal Teks lengkap
Engineering of a wireless single capacitive discharge conductivity-clamped gene electrotransfer probe for naked nucleic acid therapeutics
Pulsed electric field gene electrotransfer addresses the need for safe, directed “vector-free” delivery of DNA/mRNA therapeutics in deep tissue targets. We report the development of a disposable needle-type “electro-lens” probe for precision delivery of DNA/mRNA to tissues via translocation of…
-
Artikel Jurnal
Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer
Abstract Viral vector and lipid nanoparticle based gene delivery have limitations around spatiotemporal control, transgene packaging size, and vector immune reactivity, compromising translation of nucleic acid (NA) therapeutics. In the emerging field of DNA and particularly RNA‐based gene…