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11 hasil untuk "Ming-Rong Xie"

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  1. Artikel Jurnal

    Sphingolipids associated research in Alzheimer’s disease: an explored trends analysis

    Ming-Rong Xie; Yan-Jun Chen; Hui Yuan

    Frontiers in Aging Neuroscience, Vol. 18 · 2026 · Inggris · DOAJ Scopus

    BackgroundAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairment. Numerous studies have indicated that dysregulation of sphingolipid metabolism is closely associated with the core pathology of AD and acts as a crucial driving factor. This study…

  2. Artikel Jurnal

    Gamma-aminobutyric acid associated research in Parkinson’s disease: an exploratory trends analysis

    Sheng-Qiang Zhou; Fang Liu; Yan-Jun Chen dkk.

    Frontiers in Aging Neuroscience, Vol. 17 · 2026 · Inggris · DOAJ Scopus

    BackgroundParkinson’s disease (PD) is a neurodegenerative disease characterized by the progressive loss of dopaminergic neurons. Gamma-aminobutyric acid (GABA), as a key inhibitory neurotransmitter, participates in physiological processes such as cognition and motor control by regulating the…

  3. Artikel Jurnal

    Microglia-associated research in Parkinson’s disease: a bibliometric analysis

    Yan-Jun Chen; Ming-Rong Xie; Sheng-Qiang Zhou dkk.

    Frontiers in Aging Neuroscience, Vol. 17 · 2025 · Inggris · DOAJ Scopus

    BackgroundParkinson’s disease (PD) is a neurodegenerative disorder that predominantly affects the elderly. Evidence indicates that microglia-mediated neuroinflammation is recognized as one of the key mechanisms in PD. This study aims to analyze the key points, hotspots, and emerging frontiers in…

  4. Artikel Jurnal

    Glutamate-associated research in Parkinson’s disease: a bibliometric analysis

    Yan-Jun Chen; Ming-Rong Xie; Sheng-Qiang Zhou dkk.

    Frontiers in Aging Neuroscience, Vol. 17 · 2025 · Inggris · DOAJ Scopus

    BackgroundParkinson’s disease (PD) is a common neurodegenerative disease. As an important excitatory neurotransmitter, glutamate plays a key role in the nervous system. The imbalance of glutamate levels, the dysfunction of related receptors, and the abnormal activity of transporters are closely…

  5. Artikel Jurnal

    Synapses-associated research in Parkinson’s disease: an explored trends analysis

    Yan-Jun Chen; Ming-Rong Xie; Sheng-Qiang Zhou dkk.

    Frontiers in Aging Neuroscience, Vol. 17 · 2025 · Inggris · DOAJ Scopus

    BackgroundThe pathological features of Parkinson’s disease (PD) include the formation of Lewy bodies composed mainly of aggregated alpha-synuclein (α-Syn) and extensive neurodegeneration. Synaptic dysfunction is a key factor contributing to disease progression among the various cellular and…

  6. Artikel Jurnal

    Astrocytes-associated research in Parkinson’s disease: an explored trends analysis

    Yan-Jun Chen; Ming-Rong Xie; Sheng-Qiang Zhou dkk.

    Frontiers in Aging Neuroscience, Vol. 17 · 2025 · Inggris · DOAJ Scopus

    BackgroundParkinson’s disease (PD) is characterized pathologically by the degeneration of dopaminergic neurons and the formation of Lewy bodies. Among the various cellular and molecular mechanisms of PD, astrocyte dysfunction is one of the causes of disease development. This study aims to explore…

  7. Artikel Jurnal

    Mapping the research of mitochondria and Parkinson’s disease: a bibliometric analysis

    Yan-Jun Chen; Ming-Rong Xie; Sheng-Qiang Zhou dkk.

    Frontiers in Neurology, Vol. 15 · 2024 · Inggris · DOAJ Scopus

    BackgroundParkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder primarily affecting the elderly. Relevant studies suggest a significant connection between the mitochondria and PD. Publications exploring this connection have steadily increased in recent years. This study…

  8. Artikel Jurnal

    Research trends on neuroinflammation in Parkinson’s disease: an exploratory analysis

    Yan-Jun Chen; Ming-Rong Xie; Fang Liu dkk.

    Frontiers in Aging Neuroscience, Vol. 18 · 2026 · Inggris · DOAJ Scopus

    BackgroundNeuroinflammation is a core mechanism in the pathogenesis of Parkinson’s disease (PD). Research on PD and neuroinflammation has been steadily increasing. This study aims to explore and analyze the current status, hotspots, and future directions of neuroinflammation-associated research in…

  9. Artikel Jurnal

    Insulin-like growth factor 1 associated research in Alzheimer’s disease: an exploratory trends analysis

    Yan-Jun Chen; Ming-Rong Xie; Qin-Quan Zhu dkk.

    Frontiers in Neurology, Vol. 17 · 2026 · Inggris · DOAJ Scopus

    BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive impairment and behavioral deterioration. In recent years, the role of the insulin-like growth factor-1 (IGF-1) signaling pathway in the pathological process of AD has received increasing…

  10. Artikel Jurnal

    Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms

    Yan‐Jun Chen; Jing‐Wen Chen; Ming‐Rong Xie dkk.

    Immunity, Inflammation and Disease, Vol. 14 No. 2 · 2026 · Inggris · DOAJ Scopus

    ABSTRACT Background Parkinson's disease (PD) is a major neurodegenerative disorder. Some patients show limited response to standard therapies, driving the need for new complementary treatments. Paning I decoction (PNID), a traditional herbal formula, has shown the potential to alleviate PD…

  11. Artikel Jurnal

    Microglia associated research in depression: an exploratory trends analysis

    Yan-Jun Chen; Qin-Quan Zhu; Ming-Rong Xie dkk.

    Frontiers in Aging Neuroscience, Vol. 18 · 2026 · Inggris · DOAJ Scopus

    BackgroundDepression is a common and highly debilitating severe affective disorder. Relevant studies have indicated that microglia are closely associated with the progression of depression. This study conducts a bibliometric analysis on the research related to microglia in depression, aiming to…