4 hasil untuk "Rodolfo Blanco-Rodriguez"

CrossLabFit: A novel framework for integrating qualitative and quantitative data across multiple labs for model calibration

Rodolfo Blanco-Rodriguez; Tanya A. Miura; Esteban Hernandez-Vargas

PLOS Computational Biology, Vol. 21 No. 11 · 2025 · Inggris · PLOS Scopus

The integration of computational models with experimental data is a cornerstone for gaining insight into biomedical applications. However, parameter fitting procedures often require a vast availability and frequency of data that are challenging to obtain from a single source. Here, we present a…

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Multicompartment modeling of influenza A replication along the murine respiratory tract

Rodolfo Blanco-Rodriguez; L. America Chi; Esteban A. Hernandez-Vargas

Frontiers in Virology, Vol. 6 · 2026 · Inggris · DOAJ Scopus

Influenza A virus spreads through the respiratory tract in a compartment-specific manner, yet the mechanisms governing its progression remain unclear. Here, we investigated how viral replication and inter-compartment transport shape infection dynamics across the nose, trachea, and lungs. To address…

Computational framework for streamlining the success of sequential antibiotic therapy

Alejandro Anderson; Matthew W. Kinahan; Rodolfo Blanco-Rodriguez dkk.

npj Antimicrobials and Resistance, Vol. 3 No. 1 · 2025 · Inggris · DOAJ

Abstract Antibiotic resistance represents a growing global health crisis, diminishing the effectiveness of existing treatments and accelerating the emergence of multidrug-resistant bacterial strains. In this study, we present a mathematical framework for systematically characterizing data sets of…