28 results for "Ruby Yu"
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Housework Reduces All-Cause and Cancer Mortality in Chinese Men
Background: Leisure time physical activity has been extensively studied. However, the health benefits of non-leisure time physical activity, particular those undertaken at home on all-cause and cancer mortality are limited, particularly among the elderly. Methods: We studied physical activity in…
Also available at: DOAJ
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Correction: Housework Reduces All-Cause and Cancer Mortality in Chinese Men
Also available at: DOAJ
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Effects of a 12-Week Hatha Yoga Intervention on Metabolic Risk and Quality of Life in Hong Kong Chinese Adults with and without Metabolic Syndrome
Objective: To determine the efficacy of a 12-week Hatha yoga intervention to improve metabolic risk profiles and health-related quality of life (HRQoL) in Chinese adults with and without metabolic syndrome (MetS). Methods: We conducted a controlled trial within an university-affiliated hospital…
Also available at: DOAJ
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Determinants of the incorporation of the Integrated Care for Older People (ICOPE) model into healthcare systems - insights from Hong Kong and Malaysia
Care of older people has evolved from comprehensive geriatric assessment developed in the hospital setting in the UK and USA, to using frailty as a summary indicator, and shifting care to the community following the World Health Organization’s definition of healthy ageing using intrinsic capacity…
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The Effects of Combinations of Cognitive Impairment and Pre-frailty on Adverse Outcomes from a Prospective Community-Based Cohort Study of Older Chinese People
ObjectivesTo examine how various combinations of cognitive impairment (overall performance and specific domains) and pre-frailty predict risks of adverse outcomes; and to determine whether cognitive frailty may be defined as the combination of cognitive impairment and the presence of…
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mHealth as a Key Component of a New Model of Primary Care for Older Adults
AbstractWith population aging, an increase in total life expectancy at birth (TLE) should ideally be accompanied by an equal increase in health span (HS), or by a trend in increasing HS/TLE ratio. Hong Kong has one of the longest life expectancies in the world; however, there is a trend of…
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Using cardiorespiratory fitness to operationalize vitality: a path analysis on the hierarchical structure of intrinsic capacity
Background: There is a lack of consensus about the operationalization of vitality, which is one of the intrinsic capacity (IC) domains. In particular, no study has investigated whether cardiorespiratory fitness (CRF) can be considered a vitality indicator. Objective: To examine whether vitality is…
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Trends and characteristics of hospitalisation and mortality among centenarians in old-age homes and communities: a territory-wide study in Hong Kong, 2012–2021
Objective To examine the trends and characteristics of hospitalisation and mortality among centenarians residing in old-age homes (OAHs) and their community-dwelling counterparts in Hong Kong over the past decade.Methods This retrospective analysis used electronic admission records of all…
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Core transcriptional regulatory circuitries in cancer
Transcription factors (TFs) coordinate the on-and-off states of gene expression typically in a combinatorial fashion. Studies from embryonic stem cells and other cell types have revealed that a clique of self-regulated core TFs control cell identity and cell state. These core TFs form…
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Geriatric syndromes, multimorbidity, and disability overlap and increase healthcare use among older Chinese
Abstract Background Geriatric syndromes, multimorbidity, and disability are prevalent among ageing population. However, no study empirically examined their additive or synergistic effect on healthcare use. The present study aims to estimate overlapping prevalence of geriatric syndromes…
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Preserving intrinsic capacity in midlife women: A mixed-methods study of a personalized multicomponent intervention aligned with the WHO ICOPE framework
Background: Intrinsic capacity (IC) preservation during midlife represents a critical yet overlooked opportunity for preventing age-related functional decline. We developed WomenWellness, a 12-week personalized multicomponent intervention aligned with the WHO Integrated Care for Older People…
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Incremental predictive value of intrinsic capacity and environmental characteristics in the risk prediction of incident disability
Objective: To examine the incremental value of intrinsic capacity (IC) and environmental characteristics in the risk prediction of disability. Method: Secondary analysis was performed on a longitudinal sample of individuals aged 50 years or above. The selected subsample was ambulant and cognitively…
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Transitions in intrinsic capacity among community-dwelling older people and their associated factors: a multistate modelling analysis
Objectives: Trajectory of intrinsic capacity (IC) can be non-linear and discontinuous, which traditional linear models may not be able to handle. This study thus aimed to model the trajectory of IC as transitions between different IC states and examine their associated factors. Methods…
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Injectable microcarrier‐hydrogel composite for dental stem cell delivery and tissue regeneration
Abstract Conventional methods of stem cell therapy for tissue regeneration often face challenges, such as poor cell viability and integration posttransplantation. To address this, we proposed transplanting cells within synthetic microenvironments that maintain viability, cell phenotype, support…
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Advances in tissue engineering of cancer microenvironment-from three-dimensional culture to three-dimensional printing
Cancer treatment development is a complex process, with tumor heterogeneity and inter-patient variations limiting the success of therapeutic intervention. Traditional two-dimensional cell culture has been used to study cancer metabolism, but it fails to capture physiologically relevant cell-cell…
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Blood Pressure Variability is Associated With Lower Cognitive Function: An Elderly Cohort Study in Hong Kong
ABSTRACT Cognitive impairment is a major geriatric health issue with significant public health burdens. Emerging evidence suggests blood pressure variability (BPV), particularly its dynamic fluctuations, may contribute to cognitive impairment pathogenesis through cerebrovascular damage. This study…
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A Chinese Chan-based Mind-Body Intervention Improves Memory of Older Adults
There is growing interest in the adoption of lifestyle interventions to remediate age-related declines in memory functioning and physical and psychological health among older adults. This study aimed to investigate whether a Chinese Chan-based lifestyle intervention, the Dejian Mind-Body…