7 results for "Saefuddin Aziz"
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Journal Article Full text
Metalloproteinase-9 gene variants and risk for hypertension among ethnic Javanese
Background Hypertension is associated with endothelial-dependent vasodilation disorders, due to reduced nitric oxide (NO) availability and excessive angiotensin II (ANG-II) activation. The objective of this study was to determine the association between matrix metallopeptidase 9 (MMP-9) gene…
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Journal Article
Metalloproteinase-9 gene variants and risk for hypertension among ethnic Javanese
Background Hypertension is associated with endothelial-dependent vasodilation disorders, due to reduced nitric oxide (NO) availability and excessive angiotensin II (ANG-II) activation. The objective of this study was to determine the association between matrix metallopeptidase 9 (MMP-9) gene…
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Journal Article
Decolorization of naphthol batik effluents using immobilized enzyme of Aspergillus sp. GPN and zeolite‐activated carbon in a wastewater treatment plant (WWTP)
Industrial batik wastewater containing naphthol dyes is persistent, dark in color, and contains complex organic compounds that have the potential to pollute aquatic environments. Conventional physicochemical treatment methods are often ineffective in degrading resistant aromatic compounds and…
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Journal Article
EFEK POLIMORFISME GENA GSTP-1 TERHADAP AKTIVITAS GLUTATION S-TRANSFERASE (GST) PADA INDIVIDU TERPAPAR LOGAM BERAT TIMBAL (Effect of GSTP-1 Gene Polymorphismson Glutation S- Transferase (GST) Activity in Heavy Metals Lead-Exposed Individual)
ABSTRAK Gena GSTP-1 merupakan penghasil enzim glutation S- transferase (GST), yang berfungsi dalam proses detoksifikasi senyawa toksik di hati. Faktor keberadaan polimorfisme gena GSTP-1 akan menyebabkan penurunan ekspresi GST, sehingga proses detoksifikasi terhadap senyawa toksik akan terhambat…
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Design and evaluation of degenerate primers targeting the NS3 gene for detection of dengue virus by RT-PCR
Background: Dengue fever, caused by the dengue virus, is hyper-endemic in Indonesia. Since no protective vaccine or specific treatments are available, accurate diagnosis is crucial for the early implementation of preventive measures to limit dengue transmission and reduce economic losses. Various…
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Journal Article
Maculosin, a non-toxic antioxidant compound isolated from Streptomyces sp. KTM18
Context Streptomyces species are prolific sources of bioactive secondary metabolites known especially for their antimicrobial and anticancer activities. Objective This study sought to isolate and characterize antioxidant molecules biosynthesized by Streptomyces sp. KTM18. The antioxidant potential…
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Journal Article Full text
Mining Indonesian Microbial Biodiversity for Novel Natural Compounds by a Combined Genome Mining and Molecular Networking Approach
Indonesia is one of the most biodiverse countries in the world and a promising resource for novel natural compound producers. Actinomycetes produce about two thirds of all clinically used antibiotics. Thus, exploiting Indonesia’s microbial diversity for actinomycetes may lead to the discovery of…