10 hasil untuk "Shira Modai"

HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication.

Shira Modai; Luba Farberov; Eytan Herzig dkk.

PLoS ONE, Vol. 14 No. 1 · 2019 · Inggris · DOAJ Scopus

HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in systemic CD4+ T cell depletion, thereby impairing cell-mediated immunity. MicroRNAs are short (~22 nucleotides long), endogenous single-stranded RNA molecules that regulate gene expression by binding…

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Antiviral properties of goat milk

Moshe Rubin; Shira Modai; Shlomi Rayman dkk.

Clinical Nutrition Open Science, Vol. 37 · 2021 · Inggris · DOAJ Scopus

Summary: Goat milk is commonly used as a “grandmother's drug” in traditional therapy of oral ulcers and lesions caused by Herpes Simplex Virus type 1 (HSV-1) infection without any basic scientific study. The aim of this study is to characterize and quantify the anti-viral effect of goat milk and…

A clinically validated whole genome pipeline for structural variant detection and analysis

Nir Neerman; Gregory Faust; Naomi Meeks dkk.

BMC Genomics, Vol. 20 No. S8 · 2019 · Inggris · DOAJ Scopus

Abstract Background With the continuing decrease in cost of whole genome sequencing (WGS), we have already approached the point of inflection where WGS testing has become economically feasible, facilitating broader access to the benefits that are helping to define WGS as the new diagnostic…

Downregulation of Mir-31, Mir-155, and Mir-564 in Chronic Myeloid Leukemia Cells

Oshrat Hershkovitz Rokah; Galit Granot; Adelina Ovcharenko dkk.

PLoS ONE, Vol. 7 No. 4 · 2012 · Inggris · PLOS Scopus

Background/Aims: MicroRNAs (miRNAs) are short non-coding regulatory RNAs that control gene expression and play an important role in cancer development and progression. However, little is known about the role of miRNAs in chronic myeloid leukemia (CML). Our objective is to decipher a miRNA…

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Regulation of Cancer Aggressive Features in Melanoma Cells by MicroRNAs

Eyal Greenberg; Liat Hershkovitz; Orit Itzhaki dkk.

PLoS ONE, Vol. 6 No. 4 · 2011 · Inggris · PLOS Scopus

MicroRNAs (miRNAs) are small non-coding RNAs with regulatory roles, which are involved in a broad spectrum of physiological and pathological processes, including cancer. A common strategy for identification of miRNAs involved in cell transformation is to compare malignant cells to normal cells…

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Neuro-Epigenetic Indications of Acute Stress Response in Humans: The Case of MicroRNA-29c

Sharon Vaisvaser; Shira Modai; Luba Farberov dkk.

PLOS ONE, Vol. 11 No. 1 · 2016 · Inggris · PLOS Scopus

Stress research has progressively become more integrative in nature, seeking to unfold crucial relations between the different phenotypic levels of stress manifestations. This study sought to unravel stress-induced variations in expression of human microRNAs sampled in peripheral blood mononuclear…

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