11 results for "Stephan Dobner"

SGLT2 inhibitor therapy for transthyretin amyloid cardiomyopathy: early tolerance and clinical response to dapagliflozin

Stephan Dobner; Benedikt Bernhard; Babken Asatryan et al.

ESC Heart Failure, Vol. 10 No. 1 · 2023 · English · DOAJ Scopus

Abstract Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) improve clinical outcomes in heart failure patients with reduced and preserved left ventricular ejection fraction (LVEF), but have not yet been investigated in transthyretin amyloid cardiomyopathy (ATTR‐CM). This study aimed to…

Pump thrombosis and dynamic outflow graft compression: complications in left ventricular assist device therapy

Stephan Dobner; Christoph Gräni; Beate Hugi‐Mayr et al.

ESC Heart Failure, Vol. 8 No. 2 · 2021 · English · DOAJ Scopus

Abstract Over the past decade, left ventricular assist device (VAD) therapy has become more prevalent and increasingly safe. Severe complications, such as VAD pump thrombosis and outflow graft obstruction, are rare, yet still associated with high morbidity and mortality. Clinical presentation, VAD…

Impact of route of access and stenosis subtype on outcome after transcatheter aortic valve replacement

Julian Maier; Thomas Lambert; Thomas Senoner et al.

Frontiers in Cardiovascular Medicine, Vol. 10 · 2023 · English · DOAJ Scopus

IntroductionPrevious analyses have reported the outcomes of transcatheter aortic valve replacement (TAVR) for patients with low-flow, low-gradient (LFLG) aortic stenosis (AS), without stratifying according to the route of access. Differences in mortality rates among access routes have been…

Amyloid Transthyretin Cardiomyopathy in Elderly Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation

Stephan Dobner; Thomas Pilgrim; Daniel Hagemeyer et al.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 12 No. 16 · 2023 · English · DOAJ Scopus

Background The prevalence of calcific aortic stenosis and amyloid transthyretin cardiomyopathy (ATTR‐CM) increase with age, and they often coexist. The objective was to determine the prevalence of ATTR‐CM in patients with severe aortic stenosis and evaluate differences in presentations and outcomes…

Paroxetine‐Mediated G‐Protein Receptor Kinase 2 Inhibition in Patients With Acute Anterior Myocardial Infarction: Final 1‐Year Outcomes of the Randomized CARE‐AMI Trial

Thomas Pilgrim; Benedikt Bernhard; Monika Fürholz et al.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 11 No. 17 · 2022 · English · DOAJ Scopus

Impact of tafamidis on myocardial function and CMR tissue characteristics in transthyretin amyloid cardiomyopathy

Stephan Dobner; Benedikt Bernhard; Lorenz Ninck et al.

ESC Heart Failure, Vol. 11 No. 5 · 2024 · English · DOAJ Scopus

Abstract Aims Tafamidis improves clinical outcomes in transthyretin amyloid cardiomyopathy (ATTR‐CM), yet how tafamidis affects cardiac structure and function remains poorly described. This study prospectively analysed the effect of tafamidis on 12‐month longitudinal changes in cardiac structure…

Diagnostic performance of cardiac magnetic resonance segmental myocardial strain for detecting microvascular obstruction and late gadolinium enhancement in patients presenting after a ST-elevation myocardial infarction

Christoph Gräni; Anselm W. Stark; Kady Fischer et al.

Frontiers in Cardiovascular Medicine, Vol. 9 · 2022 · English · DOAJ Scopus

BackgroundMicrovascular obstruction (MVO) and Late Gadolinium Enhancement (LGE) assessed in cardiac magnetic resonance (CMR) are associated with adverse outcome in patients with ST-elevation myocardial infarction (STEMI). Our aim was to analyze the diagnostic performance of segmental strain for the…

Dataset on the prognostic value of cardiac biomarkers used in clinical routine in patients with severe aortic stenosis undergoing valve replacement

Fabian Barbieri; Thomas Senoner; Agne Adukauskaite et al.

Data in Brief, Vol. 29 · 2020 · English · DOAJ Scopus

Hereby, the supplemental data of the research article “Long-Term Prognostic Value of High-Sensitivity Troponin T added to N-Terminal Pro Brain Natriuretic Peptide Plasma Levels before Valve Replacement for Severe Aortic Stenosis” are presented [1]. It offers enhanced input on the predictive value…

Clinical Outcomes in Patients With Acute Pulmonary Embolism Undergoing Ultrasound‐Assisted Catheter‐Directed Thrombolysis

Dominik F. Draxler; Judith Karen Johannes; Masaaki Nakase et al.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 14 No. 9 · 2025 · English · DOAJ Scopus

Background Ultrasound‐assisted catheter‐directed thrombolysis (USAT) for acute pulmonary embolism (PE) has garnered specific interest and is commonly employed in intermediate‐risk PE to prevent cardiac decompensation and death. However, evidence supporting the effectiveness and safety of USAT in…

Promise and Peril of a Genotype‐First Approach to Mendelian Cardiovascular Disease

Babken Asatryan; Brittney Murray; Rafik Tadros et al.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 13 No. 21 · 2024 · English · DOAJ Scopus

Precision medicine, which among other aspects includes an individual's genomic data in diagnosis and management, has become the standard‐of‐care for Mendelian cardiovascular disease (CVD). However, early identification and management of asymptomatic patients with potentially lethal and manageable…

Management of transthyretin amyloidosis

Adalgisa Condoluci; Marie Théaudin; Rahel Schwotzer et al.

Swiss Medical Weekly, Vol. 151 No. 4142 · 2021 · English · DOAJ Scopus

This article was corrected and republished online on November 4, 2021. Please see Erratum (Swiss Med Wkly. 2021;151:w30104)