16 hasil untuk "Syafruddin ."

Molecular Surveillance of Dengue in Semarang, Indonesia Revealed the Circulation of an Old Genotype of Dengue Virus Serotype-1

Sukmal Fahri; Benediktus Yohan; Hidayat Trimarsanto dkk.

PLoS Neglected Tropical Diseases, Vol. 7 No. 8 · 2013 · Inggris · PLOS Scopus

Dengue disease is currently a major health problem in Indonesia and affects all provinces in the country, including Semarang Municipality, Central Java province. While dengue is endemic in this region, only limited data on the disease epidemiology is available. To understand the dynamics of dengue…

What factors do make quality improvement work in primary health care? Experiences of maternal health quality improvement teams in three Puskesmas in Indonesia

Ralalicia Limato; Patricia Tumbelaka; Rukhsana Ahmed dkk.

PLOS ONE, Vol. 14 No. 12 · 2019 · Inggris · PLOS Scopus

Background: Indonesia has been shifting from ensuring access to health services towards improving service quality. Accreditation has been used as quality assurance (QA) mechanism, first in hospitals and subsequently in primary health care facilities, including Puskesmas (community health centres)…

Distribution of Voltage-Gated Sodium Channel ( Nav ) Alleles among the Aedes aegypti Populations In Central Java Province and Its Association with Resistance to Pyrethroid Insecticides

Sayono Sayono; Anggie Puspa Nur Hidayati; Sukmal Fahri dkk.

PLOS ONE, Vol. 11 No. 3 · 2016 · Inggris · PLOS Scopus

The emergence of insecticide resistant Aedes aegypti mosquitoes has hampered dengue control efforts. WHO susceptibility tests, using several pyrethroid compounds, were conducted on Ae. aegypti larvae that were collected and raised to adulthood from Semarang, Surakarta, Kudus and Jepara in Java. The…

CRISPR/Cas9 mediated ENT2 gene knockout altered purine catabolic pathway and induced apoptosis in colorectal cell lines

Safaa M. Naes; Sharaniza Ab-Rahim; Musalmah Mazlan dkk.

PLOS One, Vol. 20 No. 8 · 2025 · Inggris · PLOS Scopus

Although purine metabolism is one of the most impacted pathways in colorectal cancer (CRC), little is known about the role of equilibrative nucleoside transporter 2 (ENT2) in CRC development and its association with the altered purine metabolism pathway. This study aimed to determine the role of…

Blood lead levels and lead toxicity in children aged 1-5 years of Cinangka Village, Bogor Regency

Yana Irawati; Haryoto Kusnoputranto; Umar Fahmi Achmadi dkk.

PLOS ONE, Vol. 17 No. 2 · 2022 · Inggris · PLOS Scopus

Lead is one of ten hazardous chemicals of public health concern and is used in more than 900 occupations, including the battery, smelting, and mining industries. Lead toxicity accounts for 1.5% (900,000) of deaths annually in the world. In Indonesia, reports of high Blood Lead Level (BLL) were…

Characterization of entomological drivers of malaria transmission in five villages, Keerom Regency, Papua, Indonesia

Ismail E. Rozi; Lepa Syahrani; Dendi H. Permana dkk.

PLOS One, Vol. 21 No. 6 · 2026 · Inggris · PLOS Scopus

Background: Keerom Regency remains one of the high-malaria-endemic regencies in Indonesia. Despite the accelerated malaria elimination strategy underway in Papua, malaria transmission in this regency has not declined. To characterize the entomological and human behavioral factors sustaining and…

Gaps in protection to Anopheles exposure in high malaria endemic regencies of Papua Province, Indonesia

Ismail E. Rozi; Lepa Syahrani; Dendi H. Permana dkk.

PLOS ONE, Vol. 20 No. 4 · 2025 · Inggris · PLOS Scopus

Background: Malaria in eastern Indonesia remains high despite significant reductions and local elimination in other parts of the country. Malaria control activities that have been implemented include early diagnosis and prompt treatment, provision of Long-lasting insecticide-treated nets (LLINs)…

Genetic regulatory axis between AGR2 and ESR1 promotes breast cancer progression

M. Aiman Mohtar; Delphine Fessart; Chia Yuh Cai dkk.

PLOS One, Vol. 21 No. 7 · 2026 · Inggris · PLOS Scopus

Anterior gradient protein 2 (AGR2), a member of the protein disulfide isomerase family, plays a critical role in endoplasmic reticulum proteostasis and has been implicated in breast cancer progression. However, the downstream regulatory programs and signaling pathways governed by AGR2 remain…

Platelet Activation Determines Angiopoietin-1 and VEGF Levels in Malaria: Implications for Their Use as Biomarkers

Judith Brouwers; Rintis Noviyanti; Rob Fijnheer dkk.

PLoS ONE, Vol. 8 No. 6 · 2013 · Inggris · PLOS Scopus

Introduction: The angiogenic proteins angiopoietin (Ang)-1, Ang-2 and vascular endothelial growth factor (VEGF) are regulators of endothelial inflammation and integrity. Since platelets store large amounts of Ang-1 and VEGF, measurement of circulation levels of these proteins is sensitive to…

Tracing the Tiger: Population Genetics Provides Valuable Insights into the Aedes ( Stegomyia ) albopictus Invasion of the Australasian Region

Nigel W. Beebe; Luke Ambrose; Lydia A. Hill dkk.

PLoS Neglected Tropical Diseases, Vol. 7 No. 8 · 2013 · Inggris · PLOS Scopus

Background: The range of the Asian tiger mosquito Aedes albopictus is expanding globally, raising the threat of emerging and re-emerging arbovirus transmission risks including dengue and chikungunya. Its detection in Papua New Guinea's (PNG) southern Fly River coastal region in 1988 and 1992 placed…

Anopheles sundaicus complex and the presence of Anopheles epiroticus in Indonesia

Din Syafruddin; Yulia E. Lestari; Dendi H. Permana dkk.

PLOS Neglected Tropical Diseases, Vol. 14 No. 7 · 2020 · Inggris · PLOS Scopus

Anopheles sundaicus s.l. is an important malaria vector primarily found in coastal landscapes of western and central Indonesia. The species complex has a wide geographical distribution in South and Southeast Asia and exhibits ecological and behavioural variability over its range. Studies on…

Correction: Anopheles sundaicus complex and the presence of Anopheles epiroticus in Indonesia

Din Syafruddin; Yulia E. Lestari; Dendi H. Permana dkk.

PLOS Neglected Tropical Diseases, Vol. 15 No. 4 · 2021 · Inggris · PLOS Scopus

An inventory of human night-biting mosquitoes and their bionomics in Sumba, Indonesia

Lepa Syahrani; Dendi H. Permana; Din Syafruddin dkk.

PLOS Neglected Tropical Diseases, Vol. 16 No. 3 · 2022 · Inggris · PLOS Scopus

Mosquitoes are important vectors that transmit pathogens to human and other vertebrates. Each mosquito species has specific ecological requirements and bionomic traits that impact human exposure to mosquito bites, and hence disease transmission and vector control. A study of human biting mosquitoes…

Human behavior determinants of exposure to Anopheles vectors of malaria in Sumba, Indonesia

Ismail E. Rozi; Lepa Syahrani; Dendi H. Permana dkk.

PLOS ONE, Vol. 17 No. 11 · 2022 · Inggris · PLOS Scopus

Malaria vector control interventions in Sumba, Indonesia, have not been able to eliminate malaria. Human drivers of exposure to Anopheles bites were investigated as part of a larger clinical trial evaluating the impact of a spatial repellent product on malaria incidence. Human behavioral…

Tiger on the prowl: Invasion history and spatio-temporal genetic structure of the Asian tiger mosquito Aedes albopictus (Skuse 1894) in the Indo-Pacific

Andrew J. Maynard; Luke Ambrose; Robert D. Cooper dkk.

PLOS Neglected Tropical Diseases, Vol. 11 No. 4 · 2017 · Inggris · PLOS Scopus

Background: Within the last century, increases in human movement and globalization of trade have facilitated the establishment of several highly invasive mosquito species in new geographic locations with concurrent major environmental, economic and health consequences. The Asian tiger mosquito…

The risk of Plasmodium vivax parasitaemia after P . falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network

Mohammad S. Hossain; Robert J. Commons; Nicholas M. Douglas dkk.

PLOS Medicine, Vol. 17 No. 11 · 2020 · Inggris · PLOS Scopus

Background: There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk and the associated determinants using an individual patient data meta-analysis in order to identify populations in which a policy of universal radical…