7 hasil untuk "Thomas Pyka"

Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain

Korbinian Krieger; Thomas Pyka; Clemens Mingels dkk.

EJNMMI Research, Vol. 15 No. 1 · 2025 · Inggris · DOAJ Scopus

Abstract Background The large neutral amino acid [18F]fluoroethoxy-L-tyrosine ([18F]FET) is a popular tracer for detection and staging of intracranial tumors by positron emission tomography (PET). While its high tumoral uptake reflects over-expression of the L-type amino acid transporter (LAT1)…

Long-axial field-of-view PET/CT: perspectives and review of a revolutionary development in nuclear medicine based on clinical experience in over 7000 patients

Ian Alberts; Hasan Sari; Clemens Mingels dkk.

Cancer Imaging, Vol. 23 No. 1 · 2023 · Inggris · DOAJ Scopus

Abstract Recently introduced long-axial field-of-view (LAFOV) PET/CT systems represent one of the most significant advancements in nuclear medicine since the advent of multi-modality PET/CT imaging. The higher sensitivity exhibited by such systems allow for reductions in applied activity and short…

Multiparametric Characterization of Intracranial Gliomas Using Dynamic [18F]FET-PET and Magnetic Resonance Spectroscopy

Thomas Pyka; Iwona Krzyzanowska; Axel Rominger dkk.

Diagnostics, Vol. 12 No. 10 · 2022 · Inggris · DOAJ Scopus

Both static and dynamic O-(2-[18F]fluoroethyl)-l-tyrosine-(FET)-PET and 1H magnetic resonance spectroscopy (MRS) are useful tools for grading and prognostication in gliomas. However, little is known about the potential of multimodal imaging comprising both procedures. We therefore acquired NAA/Cr…

Lesion conspicuity by size in [18F]FDG long-axial field-of-view PET/CT

Thomas Pyka; Luis Weissenrieder; Konstantinos Zeimpekis dkk.

EJNMMI Research, Vol. 16 No. 1 · 2026 · Inggris · DOAJ Scopus

Predictive value of clinical and 18F-FDG-PET/CT derived imaging parameters in patients undergoing neoadjuvant chemoradiation for esophageal squamous cell carcinoma

Lisa Marr; Bernhard Haller; Thomas Pyka dkk.

Scientific Reports, Vol. 12 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Aim of this study was to validate the prognostic impact of clinical parameters and baseline 18F-FDG-PET/CT derived textural features to predict histopathologic response and survival in patients with esophageal squamous cell carcinoma undergoing neoadjuvant chemoradiation (nCRT) and…

The wavelet power spectrum of perfusion weighted MRI correlates with tumor vascularity in biopsy-proven glioblastoma samples

Lukas T. Rotkopf; Benedikt Wiestler; Christine Preibisch dkk.

PLOS ONE, Vol. 15 No. 1 · 2020 · Inggris · PLOS Scopus

Background: Wavelet transformed reconstructions of dynamic susceptibility contrast (DSC) MR perfusion (wavelet-MRP) are a new and elegant way of visualizing vascularization. Wavelet-MRP maps yield a clear depiction of hypervascular tumor regions, as recently shown. Objective: The aim of this study…

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