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5 results for "Tianshi Xiao"

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  1. Journal Article

    Susceptibility breakpoint for Danofloxacin against swine Escherichia coli

    Yuqi Yang; Yixin Zhang; Jiarui Li et al.

    BMC Veterinary Research, Vol. 15 No. 1 · 2019 · English · DOAJ Scopus

    Abstract Background Improper use of antimicrobials results in poor treatment and severe bacterial resistance. Breakpoints are routinely used in the clinical laboratory setting to guide clinical decision making. Therefore, the objective of this study was to establish antimicrobial susceptibility…

  2. Journal Article

    Receptor identification and in vivo efficacy of a lytic phage vB_EcoStr-FJ63A against colistin-resistant Escherichia coli

    Tianshi Xiao; Cuncai Wang; Xiaolin Zhu et al.

    Veterinary Research, Vol. 57 No. 1 · 2026 · English · DOAJ Scopus

    Abstract Bacteriophages (phages), as natural predators of bacteria, represent promising alternatives to antibiotics. However, challenges such as narrow host range and insufficient pharmacokinetic and pharmacodynamic (PK/PD) studies restrict phage therapy. In previous work, we isolated Escherichia…

  3. Journal Article

    Pharmacokinetics and pharmacodynamics integration of danofloxacin against Eschrichia coli in piglet ileum ultrafiltration probe model

    Yuqi Yang; Ping Cheng; Tianshi Xiao et al.

    Scientific Reports, Vol. 11 No. 1 · 2021 · English · DOAJ Scopus

    Abstract Improper use of antibiotics results in poor treatment and severe bacterial resistance. In this study, ultrafiltration probes were successfully placed in the ileum of piglets with the aid of anesthetic. After the fluoroquinolone antimicrobial drug danofloxacin (DAN) was intramuscularly…

  4. Journal Article

    Wild-type cutoff for Apramycin against Escherichia coli

    Yuqi Yang; Tianshi Xiao; Jiarui Li et al.

    BMC Veterinary Research, Vol. 16 No. 1 · 2020 · English · DOAJ Scopus

    Abstract Background Apramycin is used exclusively for the treatment of Escherichia coli (E.coli) infections in swine around the world since the early 1980s. Recently, many research papers have demonstrated that apramycin has significant in vitro activity against multidrug-resistant E.coli isolated…

  5. Journal Article

    Baicalin Alleviates Lipopolysaccharide-Induced Liver Inflammation in Chicken by Suppressing TLR4-Mediated NF-κB Pathway

    Ping Cheng; Tong Wang; Wei Li et al.

    Frontiers in Pharmacology, Vol. 8 · 2017 · English · DOAJ Scopus

    As a kind of potent stimulus, lipopolysaccharide (LPS) has the ability to cause cell damage by activating toll-like receptor(TLR)4, then nuclear factor kappa B (NF-κB) translocates into the nucleus and changes the expression of related inflammatory genes. Baicalin is extracted from Radix…