22 hasil untuk "Viswanathan Mohan"

Prevalence of Depression in a Large Urban South Indian Population — The Chennai Urban Rural Epidemiology Study (Cures – 70)

Subramani Poongothai; Rajendra Pradeepa; Anbhazhagan Ganesan dkk.

PLoS ONE, Vol. 4 No. 9 · 2009 · Inggris · PLOS Scopus

Background: In India there are very few population based data on prevalence of depression. The aim of the study was to determine the prevalence of depression in an urban south Indian population. Methods and Findings: Subjects were recruited from the Chennai Urban Rural Epidemiology Study (CURES)…

Chronic Endotoxemia in Subjects with Type-1 Diabetes Is Seen Much before the Onset of Microvascular Complications

Vivekanandhan Aravindhan; Viswanathan Mohan; Namasivayam Arunkumar dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

Background: Lipopolysaccharide (LPS)/Endotoxin is hypothesized to play an important role in chronic inflammation associated with Type-1 diabetes (T1DM) and its complications. Endotoxin core antibodies (EndoCAb), LPS binding protein (LBP) and soluble CD14 (sCD14) act as modulators of LPS induced…

Validation of Smartphone Based Retinal Photography for Diabetic Retinopathy Screening

Ramachandran Rajalakshmi; Subramanian Arulmalar; Manoharan Usha dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

Aim: To evaluate the sensitivity and specificity of “fundus on phone’ (FOP) camera, a smartphone based retinal imaging system, as a screening tool for diabetic retinopathy (DR) detection and DR severity in comparison with 7-standard field digital retinal photography. Design: Single-site…

Prevalence of prediabetes and type 2 diabetes mellitus in south and southeast Asian women with history of gestational diabetes mellitus: Systematic review and meta-analysis

Chockalingam Shivashri; Wesley Hannah; Mohan Deepa dkk.

PLOS ONE, Vol. 17 No. 12 · 2022 · Inggris · PLOS Scopus

Background: The burden of Gestational Diabetes Mellitus (GDM) is very high in south Asia (SA) and southeast Asia (SEA). Thus, there is a need to understand the prevalence and risk factors for developing prediabetes and type 2 diabetes mellitus (T2DM) postpartum, in this high-risk population. Aim…

Correction: Prevalence of prediabetes and type 2 diabetes mellitus in south and southeast Asian women with history of gestational diabetes mellitus: Systematic review and meta-analysis

Chockalingam Shivashri; Wesley Hannah; Mohan Deepa dkk.

PLOS ONE, Vol. 19 No. 5 · 2024 · Inggris · PLOS Scopus

Circulating MiRNAs of ‘Asian Indian Phenotype’ Identified in Subjects with Impaired Glucose Tolerance and Patients with Type 2 Diabetes

Paramasivam Prabu; Sophie Rome; Chandrakumar Sathishkumar dkk.

PLOS ONE, Vol. 10 No. 5 · 2015 · Inggris · PLOS Scopus

Several omics technologies are underway worldwide with an aim to unravel the pathophysiology of a complex phenotype such as type 2 diabetes mellitus (T2DM). While recent studies imply a clinically relevant and potential biomarker role of circulatory miRNAs in the etiology of T2DM, there is lack of…

Decreased Prevalence of Lymphatic Filariasis among Diabetic Subjects Associated with a Diminished Pro-Inflammatory Cytokine Response (CURES 83)

Vivekanandhan Aravindhan; Viswanathan Mohan; Jayagopi Surendar dkk.

PLoS Neglected Tropical Diseases, Vol. 4 No. 6 · 2010 · Inggris · PLOS Scopus

Epidemiological studies have shown an inverse correlation between the incidence of lymphatic filariasis (LF) and the incidence of allergies and autoimmunity. However, the interrelationship between LF and type-2 diabetes is not known and hence, a cross sectional study to assess the baseline…

Assessment of front and back of pack nutrition labels of selected convenience food products and snacks available in the Indian market

Shanmugam Shobana; Gopalakrishnan Sangavi; Ramatu Wuni dkk.

PLOS ONE, Vol. 19 No. 12 · 2024 · Inggris · PLOS Scopus

Nutrition labels on packaged food items provide at-a-glance information about the nutritional composition of the food, serving as a quick guide for consumers to assess the quality of food products. The aim of the current study is to evaluate the nutritional information on the front and back of pack…

Low diet quality increases the genetic risk of high blood cholesterol levels in Asian Indian adults [CURES – 165]

Manahil M. Bineid; Dhanasekaran Bodhini; Kandaswamy Ramya dkk.

PLOS One, Vol. 21 No. 10 · 2026 · Inggris · PLOS Scopus

Background: Asian Indians face an increased burden of cardiometabolic diseases, yet the interplay between genetic predisposition and diet quality in this population remains underexplored. This study aimed to examine their interaction on cardiometabolic traits in this population. Methods: We…

Common Variants of Inflammatory Cytokine Genes Are Associated with Risk of Nephropathy in Type 2 Diabetes among Asian Indians

Tarunveer Singh Ahluwalia; Madhu Khullar; Monica Ahuja dkk.

PLoS ONE, Vol. 4 No. 4 · 2009 · Inggris · PLOS Scopus

Background: Inflammatory cytokine genes have been proposed as good candidate genes for conferring susceptibility to diabetic nephropathy. In the present study, we examined the combined effect of multiple alleles of pro inflammatory cytokine genes for determining the risk of nephropathy in type 2…

Interaction between TCF7L2 polymorphism and dietary fat intake on high density lipoprotein cholesterol

Dhanasekaran Bodhini; Szilvia Gaal; Israa Shatwan dkk.

PLOS ONE, Vol. 12 No. 11 · 2017 · Inggris · PLOS Scopus

Recent evidence suggests that lifestyle factors influence the association between the Melanocortin 4 receptor (MC4R) and Transcription Factor 7-Like 2 (TCF7L2) gene variants and cardio-metabolic traits in several populations; however, the available research is limited among the Asian Indian…

Circulating adiponectin mediates the association between omentin gene polymorphism and cardiometabolic health in Asian Indians

Karani Santhanakrishnan Vimaleswaran; Dhanasekaran Bodhini; Juanjie Jiang dkk.

PLOS ONE, Vol. 16 No. 5 · 2021 · Inggris · PLOS Scopus

Background: Plasma omentin levels have been shown to be associated with circulating adiponectin concentrations and cardiometabolic disease-related outcomes. In this study, we aim to examine the association of omentin gene polymorphism with serum adiponectin levels and cardiometabolic health status…

Development and Validation of DIANA (Diabetes Novel Subgroup Assessment tool): A web-based precision medicine tool to determine type 2 diabetes endotype membership and predict individuals at risk of microvascular disease

Viswanathan Baskar; Mani Arun Vignesh; Sumanth C. Raman dkk.

PLOS Digital Health, Vol. 4 No. 8 · 2025 · Inggris · PLOS Scopus

Background: Previous research has identified four distinct endotypes of type 2 diabetes in Asian Indians, which include Severe Insulin Deficient Diabetes (SIDD), Combined Insulin Resistant and Deficient Diabetes (CIRDD), Insulin Resistance and Obese Diabetes (IROD), and Mild Age-related Diabetes…

Comparison of multiple obesity indices for cardiovascular disease risk classification in South Asian adults: The CARRS Study

Shivani A. Patel; Mohan Deepa; Roopa Shivashankar dkk.

PLOS ONE, Vol. 12 No. 4 · 2017 · Inggris · PLOS Scopus

Background: We comparatively assessed the performance of six simple obesity indices to identify adults with cardiovascular disease (CVD) risk factors in a diverse and contemporary South Asian population. Methods: 8,892 participants aged 20–60 years in 2010–2011 were analyzed. Six obesity indices…

Causes and predictors of mortality in Asian Indians with and without diabetes–10 year follow-up of the Chennai Urban Rural Epidemiology Study (CURES - 150)

Ranjit Mohan Anjana; Ranjit Unnikrishnan; Poongkunran Mugilan dkk.

PLOS ONE, Vol. 13 No. 7 · 2018 · Inggris · PLOS Scopus

Background: The incidence and prevalence of diabetes is increasing worldwide and it is the fifth leading cause of mortality accounting for over 3.8 million deaths annually. Despite the enormity of the diabetes-related health burdens, very few studies have evaluated the factors associated with…

Blood-derived miRNA levels are not correlated with metabolic or anthropometric parameters in obese pre-diabetic subjects but with systemic inflammation

Prabu Paramasivam; Emmanuelle Meugnier; Kuppan Gokulakrishnan dkk.

PLOS ONE, Vol. 17 No. 2 · 2022 · Inggris · PLOS Scopus

As blood-derived miRNAs (c-miRNAs) are modulated by exercise and nutrition, we postulated that they might be used to monitor the effects of a lifestyle intervention (LI) to prevent diabetes development. To challenge this hypothesis, obese Asian Indian pre-diabetic patients were submitted to diet…

Correction: Blood-derived miRNA levels are not correlated with metabolic or anthropometric parameters in obese pre-diabetic subjects but with systemic inflammation

Prabu Paramasivam; Emmanuelle Meugnier; Kuppan Gokulakrishnan dkk.

PLOS ONE, Vol. 17 No. 7 · 2022 · Inggris · PLOS Scopus

Patterns of multimorbidity in India: A nationally representative cross-sectional study of individuals aged 15 to 49 years

Jonas Prenissl; Jan-Walter De Neve; Nikkil Sudharsanan dkk.

PLOS Global Public Health, Vol. 2 No. 8 · 2022 · Inggris · PLOS Scopus

There is a dearth of evidence on the epidemiology of multimorbidity in low- and middle-income countries. This study aimed to determine the prevalence of multimorbidity in India and its variation among states and population groups. We analyzed data from a nationally representative household survey…

Prevalence of chronic kidney disease and risk factors for its progression: A cross-sectional comparison of Indians living in Indian versus U.S. cities

Shuchi Anand; Dimple Kondal; Maria Montez-Rath dkk.

PLOS ONE, Vol. 12 No. 3 · 2017 · Inggris · PLOS Scopus

Background: While data from the latter part of the twentieth century consistently showed that immigrants to high-income countries faced higher cardio-metabolic risk than their counterparts in low- and middle-income countries, urbanization and associated lifestyle changes may be changing these…

Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study

Shashank R. Joshi; Ranjit Mohan Anjana; Mohan Deepa dkk.

PLoS ONE, Vol. 9 No. 5 · 2014 · Inggris · PLOS Scopus

Aim: To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India. Methods: Phase I of the Indian Council of Medical Research–India Diabetes (ICMR-INDIAB) study was conducted in a representative population of three states of India [Tamil…