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8 results for "Yu-Yu Lin"

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  1. Journal Article Full text

    Magnetic resonance imaging assessment of the lateral geniculate nucleus volume and height in patients with glaucoma: a Meta-analysis

    Hu, Hai-Jian; Chang, Yi-Li; Dai, Yang-Yang et al.

    Int J Ophthalmol · 2023 · English · PubMed Central

    AIM: To evaluate the lateral geniculate nucleus (LGN) volume and height using magnetic resonance imaging (MRI) in glaucoma patients. METHODS: Literatures retrieval was carried out through PubMed, Web of Science, Embase, and Cochrane Library. Studies that compared the volume and height of LGN in…

  2. Journal Article Full text

    HAHap: a read-based haplotyping method using hierarchical assembly

    Yu-Yu Lin; Ping Chun Wu; Pei-Lung Chen et al.

    PeerJ, Vol. 6 · 2018 · English · DOAJ Scopus

    Background The need for read-based phasing arises with advances in sequencing technologies. The minimum error correction (MEC) approach is the primary trend to resolve haplotypes by reducing conflicts in a single nucleotide polymorphism-fragment matrix. However, it is frequently observed that the…

  3. Journal Article Full text

    Improvements of Electrical Characteristics in Poly-Si Nanowires Thin-Film Transistors with External Connection of a BiFeO3 Capacitor

    Tsung-Kuei Kang; Yu-Yu Lin; Han-Wen Liu et al.

    Membranes, Vol. 11 No. 10 · 2021 · English · DOAJ Scopus

    By a sol–gel method, a BiFeO3 (BFO) capacitor is fabricated and connected with the control thin film transistor (TFT). Compared with a control thin-film transistor, the proposed BFO TFT achieves 56% drive current enhancement and 7–28% subthreshold swing (SS) reduction. Moreover, the effect of the…

  4. Journal Article Full text

    Values of macular ganglion cell-inner plexiform layer and 10-2 visual field measurements in detecting and evaluating glaucoma

    Hu, Hai-Jian; Li, Ping; Tong, Bin et al.

    Int J Ophthalmol · 2024 · English · PubMed Central

    AIM: To assess the performance of macular ganglion cell-inner plexiform layer thickness (mGCIPLT) and 10-2 visual field (VF) parameters in detecting early glaucoma and evaluating the severity of advanced glaucoma. METHODS: Totally 127 eyes from 89 participants (36 eyes of 19 healthy participants…

  5. Journal Article

    Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress

    Yi-Fang Yang; Zhao-Jing He; Han-Hsi Kuo et al.

    Cell Death Discovery, Vol. 11 No. 1 · 2025 · English · DOAJ Scopus

    Abstract Estrogen receptor-positive (ER⁺) breast cancer is commonly treated with hormone therapy; however, these tumors frequently develop drug resistance and exhibit poor responses to radiotherapy. To investigate the molecular basis of therapy resistance, we explored the role of estrogen receptor…

  6. Journal Article

    SLC25A11-mediated reprogramming of mitochondrial redox state and lipid peroxidation confers NRF2-dependent ferroptosis resistance in biliary tract cancer

    Yu-Yu Lin; Han-Hsi Kuo; Zhao-Jing He et al.

    Cellular & Molecular Biology Letters, Vol. 31 No. 1 · 2026 · English · DOAJ Scopus

    Abstract Background Biliary tract cancer is a group of highly heterogeneous and metastatic malignancies of the biliary tract. Current clinical treatment strategies and diagnostic methods need further improvement to effectively manage this disease. Methods We performed multiomics integrative and in…

  7. Journal Article

    DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts

    Ashish Goyal; Jens Bauer; Joschka Hey et al.

    Nature Communications, Vol. 14 No. 1 · 2023 · English · DOAJ Scopus

    Abstract Immunotherapies targeting cancer-specific neoantigens have revolutionized the treatment of cancer patients. Recent evidence suggests that epigenetic therapies synergize with immunotherapies, mediated by the de-repression of endogenous retroviral element (ERV)-encoded promoters, and the…