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Impact of the COVID-19 pandemic on sex-related disparities in cystic fibrosis healthcare utilization and outcomes: A population study
Background: The COVID-19 pandemic disrupted healthcare utilization and access for many, with persons living with pre-existing pulmonary conditions like cystic fibrosis (pwCF) having been the most impacted. PwCF appeared to have improvements in lung function and reduction in pulmonary exacerbations…
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The MARC SE-Africa dashboard: Joining forces to counteract emerging antimalarial resistance in South and East Africa
Regions within eastern and southern Africa (SE-Africa) carry some of the highest malaria burdens. Understanding the spatiotemporal dynamics of the emergence and spread of artemisinin (partial) resistance (ART-R) and how to mitigate ART-R is therefore of paramount importance in these areas. Here, we…
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Assessing the approach to perinatal mental health screening and treatment in maternal-child health clinics in Western Kenya
Integrating mental health care into well-attended health services, such as maternal-child health (MCH), offers a promising approach to increasing access to mental health care. To inform integration, we assessed the current approach to screening and treatment of perinatal mood and anxiety disorders…
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The impact of US Government Stop Work Order on HIV epidemic trajectory in Zimbabwe
Zimbabwe is highly dependent on United States Government (USG) funding for the HIV Response, where 42% of the HIV expenditures in 2020 were financed by the USG and in 2023, PEPFAR invested more than $200 million to support HIV programmes. In late January 2025, the USG issued a “Stop Work Order,”…
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Conditional cash transfer and mortality among interpersonal violence victims: A cohort study
Background: Interpersonal violence is a significant public health issue, increasing mortality risks for those affected. While Cash Transfer Programs offer health benefits, their role in addressing the needs of interpersonal violence victims remains unclear. This study aims to examine the…
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The stage-specific regulation and role of root-knot nematode SWEET genes
The root-knot nematode Meloidogyne incognita is a globally significant plant parasite that causes substantial crop losses. While pre-parasitic juveniles rely on innate energy reserves, later life stages acquire nutrients from host plants through specialized feeding structures. SWEET (Sugars Will…
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Factors associated with students’ unwillingness to voluntarily donate blood in the Eastern Region of Ghana
Background: The World Health Organisation advocates for voluntary blood donation (BD) as a sustainable means of maintaining adequate blood availability in healthcare facilities globally. However, the Eastern Region of Ghana experiences low voluntary BD rates among students. The study aimed to…
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Sensorimotor integration and functional mobility in early-stage Parkinson’s disease: A cross-sectional study using clinically feasible assessments
Early-stage Parkinson’s disease (PD) often features subtle sensorimotor integration deficits that may precede noticeable motor decline. This study examined how proprioceptive acuity, balance performance, and functional mobility relate to dual-task gait cost (DTC) in individuals with early-stage PD…
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Response of water and salt accumulation in vadose zone to groundwater level changes in coastal saline soils using HYDRUS-1D model
Purpose: Coastal saline soils are highly vulnerable to salinization, posing a major threat to sustainable agriculture. This study investigates how fluctuations in groundwater depth regulate water and salt dynamics in the vadose zone of a typical coastal saline area in Nanpi County, Hebei Province…
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Design and in silico evaluation of an mRNA vaccine against HTLV-1 using AI-driven reverse vaccinology approaches
Human T-lymphotropic virus type 1 (HTLV-1) is the first discovered human oncogenic retrovirus that can cause adult T-cell leukemia/lymphoma, HTLV-1-associated myelopathy/tropical spastic paraparesis, and several other diseases. Due to the poor prognosis of these diseases and the limited therapeutic…
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Stability of corneal endothelial monolayers in the presence of magnetic particles in a rotating magnetic field
Magnetic particles have significant potential as novel theranostics due to the relative ease of surface modification for targeting molecules or regions of diseased tissues, coupled with remote in vivo manipulation using an exogenous magnetic field. Employing magnetic particles within the eye is…
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Endothelial activation and stress index in risk stratification and treatment optimization for critically ill patients with acute kidney injury: A retrospective cohort study from MIMIC-Ⅳ database
Background: Endothelial dysfunction is critical in the pathogenesis of acute kidney injury (AKI). It sought to investigate the role of endothelial activation and stress index (EASIX) in risk stratification and treatment optimization for critically ill patients with AKI. Methods: Utilizing MIMIC-Ⅳ…
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Dutasteride treatment and its effect on standardized uptake values in prostate-specific membrane antigen-PET imaging: A pilot study
Background: Prostate-specific membrane antigen (PSMA)-based imaging has become an increasingly important diagnostic tool in prostate cancer, though limited by low surface expression of PSMA in some patients. Previous studies have demonstrated that dutasteride can induce PSMA expression in vitro and…
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Empirical Blaschke Mode decomposition: Algorithm and application
Periodic pulse components are common in complex signals across fields like biomedical and aerospace engineering, and their accurate extraction is crucial for monitoring. We propose a novel method, Empirical Blaschke Mode Decomposition (EBMD), which uses the Blaschke Transform to capture…
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Teacher support for generative AI use and design learning outcomes in fashion design education: A structural equation modeling study
The rapid integration of generative artificial intelligence (AI) in creative education necessitates empirical investigation of support mechanisms facilitating effective technology adoption and learning outcomes. This study examines the structural relationships among teacher support dimensions…
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Multilevel exposure to adversity across the life course and biological implications among urban postpartum women: A cohort study protocol
Maternal mortality and morbidity in the United States remain substantially higher than in other high-income countries. Evidence suggests that exposure to chronic stress and social and environmental adversity contributes to maternal health risk through interconnected biological, psychological, and…
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MS-YOLOv11: A multi-scale feature fusion network for real-time rooftop photovoltaic detection from UAV images
With the rapid proliferation of distributed solar energy, Unmanned Aerial Vehicles (UAVs) have emerged as indispensable tools for rooftop photovoltaic (PV) inspection. However, practical deployment is hindered by hierarchical challenges, including extreme scale variations of PV targets, complex…
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Migrant mothers’ experiences of postnatal depression in the UK
Background: Despite the majority of migrants coming to the UK for voluntary reasons such as study, work or family, few studies explore their experiences of mental health. Prevalence of postnatal depression (PND) is higher amongst migrant women compared with non-migrant women. This qualitative study…
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Is all greenspace created equal? Assessing the relationship of public parks and greenness on academic achievement in Washington state
In educational environments, proximity to greenspace can increase concentration, attentiveness, self-discipline, improve classroom engagement, and support cognitive development. This study contributes to this growing literature by examining the potential benefits associated with public parks on…
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Federated high order tensor fusion for privacy preserving multimodal social media analysis
The rapid evolution of social networks has positioned multimodal content, including text, images, and audio, as a pivotal medium for self-expression and public sentiment analysis. However, existing multimodal fusion methods are often limited by privacy risks, parameter redundancy, and insufficient…
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