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Journal Article Full text
Assessment of Water Treatment Sludge after using Riverbank Filtration
Enormous quantities of sludge are produced in water purification plants during process of purifying surface water. These sludges are either disposed of directly in water bodies or require further treatment methods in order to be reused. Riverbank filtration (RBF) is a water extraction method…
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Punching Shear Behavior of HPRC Slab–Corner Column Joints
Flat slab systems are widely used in modern buildings due to their architectural flexibility and construction efficiency. However, their structural performance is often governed by punching shear failure at slab–column connections, particularly at corner joints where the effective shear perimeter…
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Enhancement of the Deep Pile Cap Structural Performance: Numerical Analysis
This study builds upon previous experimental research on deep four-pile caps by performing numerical verification and extending the investigation through parametric analysis using ABAQUS (FEM). The numerical model was calibrated using results from a control specimen tested in the experimental…
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Comprehensive Assessment of Neuro-Fuzzy and Deep Learning Models for Enhanced Production Forecasting and Operational Planning in the Steel Industry
Accurate forecasting of monthly steel production is essential for maintaining efficient industrial operations and ensuring timely delivery of coil and rebar products to customers. This paper presents a comparative evaluation of two data-driven prediction methods, the Adaptive Neuro-Fuzzy Inference…
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SODA: A Balanced Dataset for Saudi Arabian Organic Date Fruits
The Kingdom of Saudi Arabia is a major producer of date palm fruit, yet publicly available and well-curated datasets that represent local varieties remain limited. We present SODA (Saudi Organic Date fruits dataset), a balanced image dataset of 13 organic Saudi date varieties: Ajwa, Medjool…
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Resilience of Biophilic Design for Urban Heat Island Mitigation in Temperate and Subtropical Cities under Intensifying Heat-Wave Conditions: A Multi-Criteria Decision Analysis Approach
Urban heat islands (UHIs) pose a growing threat to urban environments, particularly in temperate and subtropical cities that are increasingly exposed to intensifying heat-wave conditions under climate change. This phenomenon worsens air quality, increases energy demand, and raises public health…
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Functional Typology of Courtyards in Contemporary Urban Houses
This study investigates how plot morphology influences courtyard configuration in contemporary urban housing in Mosul, Iraq. Increasing urban density, reduced frontage widths, and smaller plot sizes have transformed the courtyard from a single traditional element into a morphology-responsive…
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Influence of Salt Concentration, pH, and Temperature on the Carbon Steel Mortar’s Compressive Strength and Corrosion Rates
This study aims to specify the compressive strength and carbon steel’s corrosion rates in mortar form as a function of pH, temperature, and salt concentration. Soil was used to replace varying amounts of steel (10, 20, and 30 g) to produce mortar specimens, facilitating the determination of…
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The immune-microbe-metal triad: a vicious cycle driving biomaterial corrosion in the oral inflammatory microenvironment
The interface around a dental implant behaves as a dynamic ecosystem. The metal surface, the colonizing microbiota, and the host immune network continually interact rather than remaining inert neighbors. Once this equilibrium breaks, a destructive cascade can feed on itself. This challenges the…
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Journal Article
Barcoded oligonucleotide system (BOLT) for targeted organ delivery
The therapeutic potential of oligonucleotides (oligos) is limited by insufficient delivery to extrahepatic tissues. In vitro assays often fail to accurately predict in vivo behavior, while testing each oligo candidate in animals remains inherently low throughput. Here, we conceive a barcoded…
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A logic-gated nanoplatform spatiotemporally orchestrates immunometabolic reprogramming and osteogenesis for diabetic periodontal regeneration
Achieving periodontal regeneration in diabetic periodontitis (DPD) is hindered by a self-perpetuating vicious cycle of excessive oxidative stress and adaptive immune dysfunction. Here, using clinical samples, multi-omics profiling, and DPD rat model, we identified an association between oxidative…
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Journal Article
Gas-propelled microneedles for precision transdermal therapeutics
Transdermal drug delivery is an appealing approach because it is easy to administer, bypasses first-pass metabolism, and utilizes an extensive surface area of the skin. Microneedles, as an emerging transdermal drug delivery system, offer minimal invasiveness, painlessness, and targeted in-situ…
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A multifunctional MOF-mineralized conductive hydrogel coating on zinc implants orchestrates neuro-osteogenic coupling for enhanced bone defect repair
Zinc (Zn)-based implants face critical challenges in clinical orthopedic applications due to rapid corrosion, localized Zn2+-induced cytotoxicity, and inadequate osteogenic activity. Herein, we report a metal-organic framework (MOF)-mediated mineralization strategy to engineer a multifunctional…
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Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms
Orthopaedic infections are increasingly prevalent in the aging population, posing a significant clinical and economic burden. Despite progress in antimicrobial therapies, challenges such as antibiotic resistance and superbug emergence persist. Gas therapy has emerged as a promising strategy for…
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An oral coral-like resveratrol nanocomplex protects against dry eye disease through ocular and systemic redox homeostasis
Dry eye disease (DED) is a progressive ocular disorder in which chronic inflammation and oxidative stress synergistically damage ocular tissues and impair vision. While topical anti-inflammatory and artificial tears therapies are the standard treatment for DED, their long-term application is…
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Organoid Intelligent Morphomics: Decoding the organoid morphome through artificial intelligence from phenotypic quantification to mechanistic insight
Organoids, as three-dimensional bioactive microtissues capable of recapitulating native organ architecture and function, have become valuable models in biomedical research. However, their broad adoption is constrained by subjective morphological assessment and endpoint assays that compromise…
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Biomaterials for intervertebral disc regeneration: Niche reprogramming, precision therapeutics, and structural reconstruction
Intervertebral disc degeneration (IDD) arises from coupled redox imbalance, inflammation, cellular senescence, nutrient limitation, matrix loss, and mechanical failure. Biomaterials can localize therapy within the avascular disc while combining microenvironmental control with structural support…
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Variation in avian haemosporidian infection patterns in Daurian Redstarts (Phoenicurus auroreus) across eastern China
Avian haemosporidian parasites are widespread vector-borne pathogens that can influence host fitness, survival, and population dynamics. However, infection patterns and parasite lineage diversity remain poorly documented in many Asian bird populations, particularly within single host species…
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High individual consistency in migratory strategies of American Herring Gulls (Larus smithsonianus) across multiple years
Migration is a fundamental component of the annual cycle of many bird species, largely driven by the need to access resources with seasonal availability. Birds employ diverse migratory strategies, undertaking short to long-distance migrations, presumably balancing energetic costs and risks with…
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Identifying biases in avian leucocyte profiles arising from blood sampling regime: The effects of capture stress and repeated sampling
Physiological biomarkers offer valuable insights into the relationships between physiological responses and ecological conditions, serving as powerful tools to assess the health and resilience of wild populations. Among them, leucocyte profiles are particularly informative indicators of individual…
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