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Mitophagy curtails cytosolic mtDNA-dependent activation of cGAS/STING inflammation during aging
Macroautophagy decreases with age, and this change is considered a hallmark of the aging process. It remains unknown whether mitophagy, the essential selective autophagic degradation of mitochondria, also decreases with age. In our analysis of mitophagy in multiple organs in the mito-QC reporter…
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The Surface Water and Ocean Topography Mission: A Breakthrough in Radar Remote Sensing of the Ocean and Land Surface Water
Abstract The elevations of water surfaces hold important information on the earth's oceans and land surface waters. Ocean sea surface height is related to the internal change of the ocean's density and mass associated with ocean circulation and its response to climate change. The flow rates of…
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Advancements in Generative AI: A Comprehensive Review of GANs, GPT, Autoencoders, Diffusion Model, and Transformers
The launch of ChatGPT in 2022 garnered global attention, marking a significant milestone in the Generative Artificial Intelligence (GAI) field. While GAI has been in effect for the past decade, the introduction of ChatGPT sparked a new wave of research and innovation in the Artificial Intelligence…
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Class-Incremental Learning: A Survey
Deep models, e.g., CNNs and Vision Transformers, have achieved impressive achievements in many vision tasks in the closed world. However, novel classes emerge from time to time in our ever-changing world, requiring a learning system to acquire new knowledge continually. Class-Incremental Learning…
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Counseling the Culturally Diverse: Theory and Practice
This article provides a comprehensive review of the book “Counseling the Culturally Diverse: Theory and Practice” by Sue, D., Sue, D., Neville, H. & Smith, L. 8th edition. Chapter 6, however, is authored by Christina M. Capodilupo, Ph.D, at Teachers College, Columbia University. Her name does not…
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Drivers of generative AI adoption in higher education through the lens of the Theory of Planned Behaviour
Drawing on the Theory of Planned Behaviour (TPB), this study investigates the relationship between the perceived benefits, strengths, weaknesses, and risks of generative AI (GenAI) tools and the fundamental factors of the TPB model (i.e., attitude, subjective norms, and perceived behavioural…
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Global projections of plastic use, end-of-life fate and potential changes in consumption, reduction, recycling and replacement with bioplastics to 2050
Excessive production, indiscriminate consumption, and improper disposal of plastics have led to plastic pollution and its hazardous environmental effects. Various approaches to tackle the challenges of reducing the plastic footprint have been developed and applied, such as the production of…
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EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update
OBJECTIVE: New modes of action and more data on the efficacy and safety of existing drugs in psoriatic arthritis (PsA) required an update of the EULAR 2019 recommendations for the pharmacological treatment of PsA. METHODS: Following EULAR standardised operating procedures, the process included a…
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The impact of generative AI on higher education learning and teaching: A study of educators’ perspectives
In recent months, Artificial Intelligence (AI) has had, and will continue to have, a dramatic impact on Higher Education (HE). A study conducted by researchers at a leading university in Australia surveyed 30 of their teaching staff, drawn predominantly from their teaching academy, and interviewed…
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Do you have AI dependency? The roles of academic self-efficacy, academic stress, and performance expectations on problematic AI usage behavior
Abstract Although previous studies have highlighted the problematic artificial intelligence (AI) usage behaviors in educational contexts, such as overreliance on AI, no study has explored the antecedents and potential consequences that contribute to this problem. Therefore, this study investigates…
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Hard magnetic properties in nanoflake van der Waals Fe3GeTe2
Abstract Two-dimensional van der Waals materials have demonstrated fascinating optical and electrical characteristics. However, reports on magnetic properties and spintronic applications of van der Waals materials are scarce by comparison. Here, we report anomalous Hall effect measurements on…
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The extracellular matrix as hallmark of cancer and metastasis: From biomechanics to therapeutic targets
The extracellular matrix (ECM) is essential for cell support during homeostasis and plays a critical role in cancer. Although research often concentrates on the tumor's cellular aspect, attention is growing for the importance of the cancer-associated ECM. Biochemical and physical ECM signals affect…
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Electrospinning: Processes, Structures, and Materials
Electrospinning is a simple and affordable method of producing nanofibers, offering a large specific surface area and highly porous structures with diameters ranging from nanometers to micrometers. This process relies on an electrostatic field, providing precise control over the fiber dimensions…
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Municipal solid waste management challenges in developing regions: A comprehensive review and future perspectives for Asia and Africa
The rapid urbanization witnessed in developing countries in Asia and Africa has led to a substantial increase in municipal solid waste (MSW) generation. However, the corresponding disposal strategies, along with constraints in land resources and finances, compounded by unorganized public behaviour…
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ECCO Guidelines on Therapeutics in Crohn’s Disease: Medical Treatment
Crohn’s disease [CD] is a chronic inflammatory bowel disease [IBD] that can result in progressive bowel damage and disability.1 CD can affect individuals of any age, from children to the elderly,2,3 and may cause significant morbidity and impact on quality of life [QoL]. The precise aetiology of CD…
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Artikel Jurnal
Soil organic matter priming: The pH effects
Priming of soil organic matter (SOM) decomposition by microorganisms is a key phenomenon of global carbon (C) cycling. Soil pH is a main factor defining priming effects (PEs) because it (i) controls microbial community composition and activities, including enzyme activities, (ii) defines SOM…
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Artikel Jurnal Teks lengkap
Transcatheter or surgical aortic valve implantation: 10-year outcomes of the NOTION trial
BACKGROUND AND AIMS: Transcatheter aortic valve implantation (TAVI) has become a viable treatment option for patients with severe aortic valve stenosis across a broad range of surgical risk. The Nordic Aortic Valve Intervention (NOTION) trial was the first to randomize patients at lower surgical…
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