7 hasil untuk "Hannu Larjava"
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Artikel Jurnal
Beyond the clot: how the biomolecular landscape of platelet-rich fibrin directs fibroblast functions
Platelet-Rich Fibrin (PRF) is a second-generation autologous blood concentrate widely applied in regenerative medicine and dentistry for its wound-healing potential. Its clinical applications span dermatology, plastic surgery, periodontology, implantology, and oral maxillofacial surgery, with…
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Artikel Jurnal
Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures
Abstract Standard cell cultures are performed in aqueous media with a low macromolecule concentration compared to tissue microenvironment. In macromolecular crowding (MMC) experiments, synthetic polymeric crowders are added into cell culture media to better mimic macromolecule concentrations found…
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Artikel Jurnal
Decontamination of multispecies oral biofilm from rough implant surface by airflow with glycine
Abstract Objectives Decontamination of biofilm‐colonized rough implant surfaces remains challenging. We investigated the effect of airflow with glycine powder (AFG) on decontamination of mature oral multispecies biofilm from a sandblasted and acid etched (SLA) titanium surface. Materials and…
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Artikel Jurnal
Calcified carotid artery atheroma on standard dental radiographs: A public health opportunity for cardiovascular risk reduction
Objective: Calcified carotid artery atheroma (CCAA) can be identified incidentally on standard dental panoramic radiographs (DPRs). We sought to (1) determine the prevalence of CCAA on DPRs in a general dental population and (2) establish the proportion of patients in whom this would represent a…
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Artikel Jurnal
Gingival epithelial cell-derived microvesicles activate mineralization in gingival fibroblasts
Abstract Soft tissue calcification occurs in many parts of the body, including the gingival tissue. Epithelial cell-derived MVs can control many functions in fibroblasts but their role in regulating mineralization has not been explored. We hypothesized that microvesicles (MVs) derived from gingival…
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Artikel Jurnal
Altered composition of the oral microbiome in integrin beta 6-deficient mouse
In periodontal disease (PD), bacterial biofilms suppress β6 integrin expression transforming growth factor-β1 signaling, resulting in gingival inflammation and bone loss. β6 integrin-null (Itgb6−/−) mice develop spontaneous PD. The aim of this study was to unravel potential differences in oral…
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Artikel Jurnal
Scanning electron microscopic analysis of adherent bacterial biofilms associated with peri‐implantitis
Abstract Objectives Peri‐implantitis (PI) is caused by bacteria in the peri‐implant space but the consensus on microbial profile is still lacking. Current microbial sampling of PI lesions has largely focused on analyzing bacterial species that have been shed from the implant surface and captured in…