9 hasil untuk "Chebly Dagher"
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Artikel Jurnal Teks lengkap
Level 3 Cardiopulmonary Exercise Testing to Guide Therapeutic Decisions in Non-Severe Pulmonary Hypertension with Lung Disease
Inhaled treprostinil is approved for the treatment of pulmonary hypertension-associated interstitial lung disease (PH-ILD); however, it has not shown significant benefit in patients with a pulmonary vascular resistance (PVR) < 4 WU. As such, treatment for non-severe PH-ILD remains controversial. A…
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Artikel Jurnal
Primary Pleural Tuberculosis Presenting With Noncaseating Granulomas: A Diagnostic Challenge
Tuberculous pleural effusion is the second most common form of extrapulmonary tuberculosis after tuberculous lymphadenitis. Despite its frequency, diagnosis remains challenging due to its paucibacillary nature, and confirmation often requires invasive procedures. We report a 26-year-old male with…
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Comparison of Infection Risks Between Intravenous and Subcutaneous Treprostinil in Patients with Pulmonary Hypertension
Background: Treprostinil, a prostacyclin analog, is used to manage pulmonary hypertension (PH) through continuous intravenous (IV) infusion via a central venous catheter (CVC) or continuous subcutaneous (SC) infusion via a small infusion pump connected to a catheter. This study compares the…
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An Abbreviated Assessment Tool for Detection of Pulmonary Hypertension in Patients With Interstitial Lung Disease
ABSTRACT Pulmonary hypertension (PH) is a major complication of interstitial lung disease (ILD) and is associated with increased morbidity and mortality. Early recognition of PH in ILD is crucial for guiding diagnostic evaluation, initiating treatment, and considering lung transplantation. The…
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Artikel Jurnal Teks lengkap
Rapid Inpatient Uptitration of Inhaled Treprostinil in PH-ILD Patients with Severe Phenotype
Pulmonary hypertension associated with interstitial lung disease (PH-ILD) is a progressive condition with limited treatment options and associated with high mortality rates. Inhaled treprostinil (iTre) is the only approved therapy for PH-ILD and has been shown to improve exercise capacity and delay…
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Artikel Jurnal Teks lengkap
Efficacy and Safety of Selexipag Treatment in Connective Tissue Disease-Associated Pulmonary Arterial Hypertension with Concomitant Interstitial Lung Disease
Patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) and concomitant interstitial lung disease (ILD) are particularly challenging to manage due to concerns about ventilation–perfusion mismatch with systemic vasodilators. In this case series, we evaluated the…
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Artikel Jurnal Teks lengkap
Development of a Tool to Assess the Severity of Pulmonary Hypertension in Patients with Interstitial Lung Disease: A Guide to Assist Therapeutic Choices
Background: Pulmonary hypertension (PH) is a frequent complication in patients with interstitial lung disease (ILD); its occurrence results in significant morbidity and mortality. Currently approved treatment options for PH-ILD include inhaled prostacyclin therapy, although this approach may be…
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Artikel Jurnal
Noninvasive Gas Exchange Determinants of Exercise Hemodynamics in Non‐Severe Pulmonary Hypertension Associated With Interstitial Lung Disease
ABSTRACT Level 3 cardiopulmonary exercise testing (CPET) can unmask the dynamic burden of pulmonary vascular disease (PVD), while submaximal exercise testing offers a simpler, noninvasive alternative. Emerging markers such as a gas‐exchange derived estimate of pulmonary vascular capacitance (GXCAP)…
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Artikel Jurnal
Use of Sotatercept to Facilitate Transition From Intravenous to Oral Prostacyclin Therapy
ABSTRACT Pulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary vascular resistance (PVR) leading to right ventricular failure and high mortality. Parenteral prostacyclin therapy remains the cornerstone for high‐risk patients but is limited by…