9 hasil untuk "Dimitrios ZIOGAS"
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Artikel Jurnal Teks lengkap
Cultivating ethnocultural empathy in healthcare: The effects of multilingualism and cross-cultural experiences
Introduction: Empathy is a multidimensional construct essential to effective healthcare delivery, encompassing general, clinical, and ethnocultural components. While the importance of empathy in clinical settings is well-established, limited research has examined how these distinct dimensions…
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Clinical considerations about the coexistence of melanoma and chronic lymphocytic leukemia in the era of targeted therapies, triggered by rare clinical scenarios. A case series and review of the literature
The epidemiologic correlation of melanoma and chronic lymphocytic leukemia (CLL) has been the subject of several population studies. In the present article, through the presentation of five illustrative cases of patients with melanoma and CLL, several aspects of this complex relationship are…
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Revealing Insights: A Comprehensive Overview of Gastric Outlet Obstruction Management, with Special Emphasis on EUS-Guided Gastroenterostomy
Gastric outlet obstruction (GOO) poses a common and challenging clinical scenario, characterized by mechanical blockage in the pylorus, distal stomach, or duodenum, resulting in symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its diverse etiology encompasses both benign and…
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Artikel Jurnal Teks lengkap
EUS-Guided Diagnosis of Gastric Subepithelial Lesions, What Is New?
Gastric subepithelial lesions (SELs) are intramural lesions that arise underneath the gastric mucosa. SELs can be benign, but can also be malignant or have malignant potential. Therefore, correct diagnosis is crucial. Endosonography has been established as the diagnostic gold standard. Although the…
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Evaluation of the Revised International Staging System in an independent cohort of unselected patients with multiple myeloma
The Revised International Staging System (R-ISS) was recently introduced in order to improve risk stratification over that provided by the widely used standard International Staging System. In addition to the parameters of the standard system, the R-ISS incorporates the presence of chromosomal…
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Cardiac and renal complications of carfilzomib in patients with multiple myeloma
Abstract: Clinical trials with carfilzomib have indicated a low but reproducible incidence of cardiovascular and renal toxicities. Among 60 consecutive myeloma patients treated with carfilzomib-based regimens who were thoroughly evaluated for cardiovascular risk factors, 12% (95% confidence…
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Artikel Jurnal
Real-World efficiency of pembrolizumab in metastatic melanoma patients following adjuvant anti-PD1 treatment
Background: Postoperative treatment of patients with either BRAF/MEK inhibitors or anti-PD1 antibodies in the adjuvant setting results in improved recurrence free survival and has therefore become a standard of care for most patients with resected stage III melanoma. For patients who need systemic…
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Implementation of a 1021-gene liquid biopsy assay for real-world tumor genomic profiling in oncology practice
Abstract The application of advanced next-generation sequencing (NGS) technologies in the analysis of circulating tumor DNA (ctDNA) enabled the comprehensive evaluation of tumor-derived alterations in the bloodstream. In this study, we evaluated the analytical performance and clinical utility of a…
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Artikel Jurnal
BRAF/MEK inhibitor rechallenge in patients with non-resectable or metastatic BRAF V600-mutated melanoma: A stratified, controlled, retrospective EUMelaReg multicenter study
Background: Therapeutic options for BRAFV600-mutant melanoma in patients who progress on BRAF/MEK-inhibitors (BRAF/MEKi) and immune-checkpoint-inhibitor (ICI) therapy, are limited. We conducted a retrospective registry study to investigate post-ICI rechallenge with BRAF/MEKi, stratified by type of…