14 hasil untuk "Foad Alzoughool"
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Artikel Jurnal
Vitamin D and Breast Cancer: Latest Evidence and Future Steps
Vitamin D (the sunshine vitamin) plays a vital role in calcium homeostasis, skeletal metabolism, and immune, cardiovascular, and reproductive systems’ functions. The worldwide prevalence of vitamin D deficiency is approximately 1 billion. Vitamin D deficiency is a serious health problem with…
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The Human Coronavirus Disease COVID-19: Its Origin, Characteristics, and Insights into Potential Drugs and Its Mechanisms
The emerging coronavirus disease (COVID-19) swept across the world, affecting more than 200 countries and territories. Genomic analysis suggests that the COVID-19 virus originated in bats and transmitted to humans through unknown intermediate hosts in the Wuhan seafood market, China, in December of…
Juga tersedia di: OpenAlex
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Optimal therapeutic adropin dose intervention in mice and rat animal models: A systematic review
Background and Aim: Adropin is a hormone encoded by the Enho gene, which is associated with energy homeostasis. Preclinical studies using animal models have shown that adropin plays a role in enhancing glucose homeostasis and dyslipidemia. Lately, several studies on animal models have been…
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Associations of pre-existing cardiovascular morbidity with severity and the fatality rate in COVID-19 patients: a systematic review and meta-analysis
Objectives The aim of this study was to evaluate the association of pre-existing cardiovascular comorbidities, including hypertension and coronary heart disease, with coronavirus disease 2019 (COVID-19) severity and mortality. Methods PubMed, ScienceDirect, and Scopus were searched between January…
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Artikel Jurnal
Linkage Between Obesity Leptin and Breast Cancer
Many cancers might be influenced by obesity, including breast cancer, the leading cause of cancer death among women. Obesity is a complex state associated with multiple physiological and molecular changes capable of modulating the behavior of breast tumor cells and the surrounding microenvironment…
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The Multifaceted Role of Irisin in Neurological Disorders: A Systematic Review Integrating Preclinical Evidence with Clinical Observations
Background: Irisin, an exercise-induced myokine, has emerged as a potent neuroprotective factor, though a systematic synthesis of its role across neurological disorders is lacking. This review systematically evaluates clinical and preclinical evidence on irisin’s association with neurological…
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The optimal therapeutic irisin dose intervention in animal model: A systematic review
Background and Aim: Irisin, a novel myocyte-secreted hormone, was proposed to mediate some of the beneficial effects of exercise such as browning of adipocytes, thermogenesis, and metabolic homeostasis. Recently, several animals' models' studies have been performed to investigate the therapeutic…
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Artikel Jurnal Teks lengkap
The Role of Interventional Irisin on Heart Molecular Physiology
Irisin, encoded by the FNDC5 (fibronectin type III domain containing 5) gene, is a novel myokine that has been implicated as an essential mediator of exercise benefits. Effects of irisin on heart physiology is still ambiguous. This study aimed to evaluate the impact of exogenous administration of…
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Therapeutic effects of skin repair plus ointment on molecular and morphological changes in burn wounds: A rat model
Skin Repair Plus Ointment (Remanco) is an advanced formulation of the traditional Jordanian cream, which has been used for treating burn injuries and has served as an alternative remedy in northern Jordan for several decades. In this study, we sought to investigate the therapeutic effects of…
Juga tersedia di: DOAJ
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Impact of Sustained Exogenous Irisin Myokine Administration on Muscle and Myocyte Integrity in Sprague Dawley Rats
Irisin is an exercise-induced myokine implicated as a fundamental mediator of physical activity benefits. The aim of the present study was to investigate the role of the chronic administration model of irisin on the physiological and molecular status of skeletal muscle. A total of 20 female Sprague…
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Artikel Jurnal
Body image and attitudes toward cosmetic surgeries among female college students in the United Arab Emirates: A cross-sectional study
Background: Due to the continuously increasing popularity of cosmetic surgeries, the influence of physical and facial beauty is pervasive worldwide. It encourages females to seek to meet specific beauty standards and not be content with their natural features. This study aimed to assess knowledge…
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Metagenomic Signatures of Colorectal Cancer in the Jordanian Population: A Regional Case-Control Analysis Using 16S rRNA Profiling
The gut microbiota plays a pivotal role in developing colorectal cancer (CRC) through interactions with host immunity, metabolism, and inflammation. However, microbiome-based studies remain scarce in Middle Eastern populations, limiting regional insights into microbial signatures associated with…