4 hasil untuk "Ignas Lebedis"
Menampilkan 1–4 · 0,30 detik · RSS
-
Artikel Jurnal
Effect of HIF-1α inhibitor LW6 on chondrogenic properties of mesenchymal stromal cells and chondrocytes in cell sheets under physioxia
Abstract Background Hypoxia-inducible factor 1 (HIF-1) plays a central role in cartilage homeostasis, and its modulation may influence the performance of cell-based therapies. LW6, an inhibitor of HIF-1α and a potential anti-cancer therapeutic, has not been previously evaluated in cartilage…
-
Artikel Jurnal
Menstrual blood-derived mesenchymal stromal cell extracellular vesicles – a potential tool for tissue regeneration and disease detection
Menstrual blood-derived mesenchymal stromal cells (MenSCs) have emerged as a novel source for regenerative medicine, offering a unique alternative to traditional stem cell types, including adipose-derived and bone marrow-derived mesenchymal stromal cells. MenSCs are characterized by their…
-
Artikel Jurnal Teks lengkap
Menstrual Blood-Derived Stem Cell Paracrine Factors Possess Stimulatory Effects on Chondrogenesis In Vitro and Diminish the Degradation of Articular Cartilage during Osteoarthritis
Articular cartilage is an avascular tissue with a limited capacity for self-regeneration, leading the tissue to osteoarthritis (OA). Mesenchymal stem cells (MSCs) are promising for cartilage tissue engineering, as they are capable of differentiating into chondrocyte-like cells and secreting a…
-
Artikel Jurnal
Menstrual blood-derived mesenchymal stromal cell extracellular vesicles stimulate chondrocytes and cartilage extracellular matrix synthesis in vitro
Abstract Human mesenchymal stromal cells are frequently studied for the development of novel technologies for preventing osteoarthritis development or repairing cartilage tissue after traumas. Menstrual blood-derived mesenchymal stromal cells (MenSCs) are less studied, however, they possess a…