48 hasil untuk "Jonathan Cook"
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Artikel Jurnal
War on Palestine: How the fates of Gaza and Julian Assange are sealed together
Commentary: Were they being properly reported, two critically important court hearings in February 2024, in London and The Hague, would expose the US ‘rules-based order’ as a hollow sham. Both posed globe-spanning threats to our most basic freedoms. Neither received more than perfunctory coverage…
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Artikel Jurnal
Probing the mechanism of peptidoglycan amidase activation by FtsEX-EnvC
ABSTRACT The FtsEX-EnvC-AmiA/B system is a key component of the E. coli cell division machinery that directs breakage of the peptidoglycan layer during separation of daughter cells. Structural and mechanistic studies have shown that ATP binding by FtsEX in the cytoplasm drives periplasmic…
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Artikel Jurnal
Partners in learning: Redefining mentorship for a learning organization
Mentorship programmes are popular for the development of black managers in South Africa. In the literature, controversy surrounds attempts to institutionalize mentorship. In this article it is argued that the concept of a learning partnership should replace that of mentorship, particularly in what…
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Artikel Jurnal Teks lengkap
Cx26 keratitis ichthyosis deafness syndrome mutations trigger alternative splicing of Cx26 to prevent expression and cause toxicity in vitro
The Cx26 mRNA has not been reported to undergo alternative splicing. In expressing a series of human keratitis ichthyosis deafness (KID) syndrome mutations of Cx26 (A88V, N14K and A40V), we found the production of a truncated mRNA product. These mutations, although not creating a cryptic splice…
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Artikel Jurnal
Lightweight Cryptanalysis of IoT Encryption Algorithms: Is Quota Sampling the Answer?
Rapid growth in the number of small sensor devices known as the Internet of Things (IoT) has seen the development of lightweight encryption algorithms. Two well-known lightweight algorithms are SIMON and SIMECK which have been specifically designed for use on resource-constrained IoT devices. These…
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Artikel Jurnal
Security and Privacy for Low Power IoT Devices on 5G and Beyond Networks: Challenges and Future Directions
The growth in the use of small sensor devices, commonly known as the Internet of Things (IoT), has resulted in unprecedented amounts of data being generated and captured. With the rapidly growing popularity of personal IoT devices, the collection of personal data through such devices has also…
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Artikel Jurnal
RAID-Crypt: Rounding Alignment of Intermediate Differentials for Cryptanalysis of Lightweight Encryption
The first lightweight encryption algorithms suitable for the Internet of Things (IoT), SIMON and SPECK, were introduced in 2013 and were immediately subjected to security evaluations utilising cryptanalysis techniques. However, cryptanalysis is inefficient, and while heuristic and sampling methods…
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Artikel Jurnal Teks lengkap
Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates.
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of poliovirus. Despite the importance of this…
Juga tersedia di: PLOS
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Artikel Jurnal
Case report: Diffuse hyperplastic perilobar nephroblastomatosis complicated by a unilateral Wilms tumour: diagnosis, treatment and follow-up
Abstract Background Nephroblastomatosis is an uncommon pathologic process characterized by the presence of persistent embryonic nephrogenic rests. Progression to Wilms tumour occurs in an estimated 35% of patients. Cure rates are based on histologic findings and disease stage and have improved from…
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Artikel Jurnal Teks lengkap
The Design Help Desk: A collaborative approach to design education for scientists and engineers.
Visual design, learning sciences, and nanotechnology may be strange bedfellows; yet, as this paper highlights, peer interaction between a designer and a scientist is an effective method for helping scientists acquire visual design skills. We describe our findings from observing twelve sessions at…
Juga tersedia di: PLOS
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Artikel Jurnal
Outcome measures in forensic mental health services: A systematic review of instruments and qualitative evidence synthesis
AbstractBackgroundOutcome measurement in forensic mental health services can support service improvement, research, and patient progress evaluation. This systematic review aims to identify instruments available for use as outcome measures in this field and assess the evidence for the most common…
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Artikel Jurnal
The implementation of a Cardiac Scientist Led Heart Failure diagnosis clinic for non-urgent suspected heart failure referrals
Abstract Background NICE guidelines suggest that patients with suspected heart failure (HF) and an NT-proBNP between 400-2,000ng/l have specialist assessment and transthoracic echocardiography within 6 weeks. Typically, pathways require significant coordination of a multidisciplinary team, with…
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Artikel Jurnal
A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials
Abstract Adverse events suffer from poor reporting within randomised controlled trials, despite them being crucial to the evaluation of a treatment. A recent update to the CONSORT harms checklist aims to improve reporting by providing structure and consistency to the information presented. We…
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Artikel Jurnal
Increasing age and tear size reduce rotator cuff repair healing rate at 1 year: Data from a large randomized controlled trial
Background and purpose — There is a need to understand the reasons why a high proportion of rotator cuff repairs fail to heal. Using data from a large randomized clinical trial, we evaluated age and tear size as risk factors for failure of rotator cuff repair. Patients and methods — Between 2007…
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Artikel Jurnal
Injection versus Decompression for Carpal Tunnel Syndrome-Pilot trial (INDICATE-P)—protocol for a randomised feasibility study
Abstract Background Carpal tunnel syndrome (CTS) is the commonest peripheral nerve disorder in the UK, with over 52,996 carpal tunnel decompressions performed in 2011. By 2030, this figure is estimated to double. Whilst evidence supports conservative measures for mild symptoms, and early surgery…
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Artikel Jurnal
Structural characterization of the YbbAP-TesA ABC transporter identifies it as a lipid hydrolase complex that extracts hydrophobic compounds from the bacterial inner membrane.
Type VII ABC transporters are ATP-powered membrane protein complexes that drive key biological processes in the bacterial cell envelope. In Escherichia coli, three of the four Type VII ABC systems have been extensively characterized, including: the FtsEX-EnvC cell division complex, the LolCDE-LolA…
Juga tersedia di: DOAJ
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Artikel Jurnal
A meta-analysis of temporal changes of response in the placebo arm of surgical randomized controlled trials: an update
Abstract Background Temporal changes in the placebo arm of randomized controlled trials (RCTs) have not been thoroughly investigated, despite the fact that results of RCTs depend on the comparison between arms. Methods In this update of our earlier systematic review and meta-analysis, we set out to…