28 hasil untuk "Kenneth Chan"

Time Series Forecasting for Air Quality with Structured and Unstructured Data Using Artificial Neural Networks

Kenneth Chan; Paul Matthews; Kamran Munir

Atmosphere, Vol. 16 No. 3 · 2025 · Inggris · DOAJ Scopus

Various machine learning algorithms exist to predict air quality, but they can only analyse structured data gathered from monitoring stations. However, the concentration of certain pollutants, such as PM2.5 and PM10, can be visually significant when there is a marked difference in their levels…

Management of Orbital and Periorbital Venous Malformation

Lara A. Benoiton; Kenneth Chan; Frederica Steiner dkk.

Frontiers in Surgery, Vol. 4 · 2017 · Inggris · DOAJ Scopus

BackgroundTo review our management of common venous malformation (VM) affecting the orbit and/or periorbital area.MethodsConsecutive patients with orbital and/or periorbital VM were identified from our vascular anomalies database. Demographic details of the patients, anatomic site(s) affected…

Internal Carotid Artery Ectasia: The Value of Imaging Studies Prior to Biopsy of a Retropharyngeal Mass

Kenneth Chan; Polly S Richards; Mike G Dilkes

Journal of Surgical Case Reports, Iss 9, p 4 (2010) · 2010 · Inggris · DOAJ Scopus

The presence of retropharyngeal tissue mass often raises the suspicion of malignancy, especially in elderly patients. This prompts urgent biopsy to investigate tissue histology. We discuss a case where this is contraindicated as the retropharyngeal mass was illustrated by CT scanning and confirmed…

Machine learning in calibrating tropical cyclone intensity forecast of ECMWF EPS

Ming Hei Kenneth Chan; Wai Kin Wong; Kin Chung Au‐Yeung

Meteorological Applications, Vol. 28 No. 6 · 2021 · Inggris · DOAJ Scopus

Abstract Intensity prediction of tropical cyclones (TC) has been one of the major challenges for the operational forecast and warning service, as well as consequential assessment of impacts including high winds, storm surge and heavy rainfall caused by TC. With the advances in global numerical…

Microwave-assisted sample preparation for rapid and sensitive analysis of H. pylori lipid A applicable to a single colony[S]

Ping Zhou; Vandana Chandan; Xin Liu dkk.

Journal of Lipid Research, Vol. 50 No. 9 · 2009 · Inggris · DOAJ Scopus

The lipid A of Gram-negative bacteria plays a major role in the pathogenesis of bacterial infections. Lipid A diversity is observed both in the number and length of fatty-acid side chains and in the presence of terminal phosphate residues and associated modifications. In this report, we describe a…

BioNanoAnalyst: a visualisation tool to assess genome assembly quality using BioNano data

Yuxuan Yuan; Philipp E. Bayer; Armin Scheben dkk.

BMC Bioinformatics, Vol. 18 No. 1 · 2017 · Inggris · DOAJ Scopus

Abstract Background Reference genome assemblies are valuable, as they provide insights into gene content, genetic evolution and domestication. The higher the quality of a reference genome assembly the more accurate the downstream analysis will be. During the last few years, major efforts have been…

Human Growth Hormone Delivery with a Microneedle Transdermal System: Preclinical Formulation, Stability, Delivery and PK of Therapeutically Relevant Doses

Mahmoud Ameri; Miryam Kadkhodayan; Joe Nguyen dkk.

Pharmaceutics, Vol. 6 No. 2 · 2014 · Inggris · DOAJ Scopus

This study evaluated the feasibility of coating formulated recombinant human growth hormone (rhGH) on a titanium microneedle transdermal delivery system, Zosano Pharma (ZP)-hGH, and assessed preclinical patch delivery performance. Formulation rheology and surface activity were assessed by…

Daisychain: Search and Interactive Visualisation of Homologs in Genome Assemblies

Oliver Schliebs; Chon-Kit Kenneth Chan; Philipp E. Bayer dkk.

Agronomy, Vol. 11 No. 12 · 2021 · Inggris · DOAJ Scopus

Daisychain is an interactive graph visualisation and search tool for custom-built gene homology databases. The main goal of Daisychain is to allow researchers working with specific genes to identify homologs in other annotation releases. The gene-centric representation includes local gene…

Pre-Outplacement Perceptions of Dental Students Regarding Rural Oral Health Practice and Associated Factors

Menaka Abuzar; Felicity Crombie; Karin Bishara dkk.

Dentistry Journal, Vol. 8 No. 1 · 2020 · Inggris · DOAJ Scopus

Rural outplacement programs have been offered by Australian universities to encourage dental students to consider rural careers. The dental curricula should be designed to provide graduates with a good understanding of oral health issues that rural oral health care workers face. Pre-outplacement…

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease

Kenneth Chan; Xiangyuan Pu; Pratik Sandesara dkk.

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6 No. 11 · 2017 · Inggris · DOAJ Scopus

BackgroundGenome‐wide association studies identified ADAMTS7 as a risk locus for coronary artery disease (CAD). Functional studies suggest that ADAMTS7 may promote cellular processes in atherosclerosis. We sought to examine the association between genetic variation at ADAMTS7 and measures of…

Transcriptomic Changes in Coral Holobionts Provide Insights into Physiological Challenges of Future Climate and Ocean Change.

Paulina Kaniewska; Chon-Kit Kenneth Chan; David Kline dkk.

PLoS ONE, Vol. 10 No. 10 · 2015 · Inggris · DOAJ Scopus

Tropical reef-building coral stress levels will intensify with the predicted rising atmospheric CO2 resulting in ocean temperature and acidification increase. Most studies to date have focused on the destabilization of coral-dinoflagellate symbioses due to warming oceans, or declining calcification…

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Evaluation of Adjuvant Activity and Bio-Distribution of Archaeosomes Prepared Using Microfluidic Technology

Yimei Jia; Gerard Agbayani; Vandana Chandan dkk.

Pharmaceutics, Vol. 14 No. 11 · 2022 · Inggris · DOAJ Scopus

Archaeosomes, composed of sulfated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. They have classically been prepared using a thin-film hydration method with an average particle size of…

Right ventricular function declines prior to left ventricular ejection fraction in hypertrophic cardiomyopathy

Masliza Mahmod; Betty Raman; Kenneth Chan dkk.

Journal of Cardiovascular Magnetic Resonance, Vol. 24 No. 1 · 2022 · Inggris · DOAJ Scopus

Abstract Background The right ventricle (RV) in hypertrophic cardiomyopathy (HCM) tends to be neglected, as previous efforts have predominantly focused on examining the prognostic value of left ventricular (LV) abnormalities. The objectives of this study were to assess RV function in HCM, changes…

Normal high-sensitivity cardiac troponin for ruling-out inpatient mortality in acute COVID-19

Alexander Liu; Robert Hammond; Kenneth Chan dkk.

PLOS ONE, Vol. 18 No. 4 · 2023 · Inggris · PLOS Scopus

Introduction: Assessment of inpatient mortality risk in COVID-19 patients is important for guiding clinical decision-making. High sensitivity cardiac troponin T (hs-cTnT) is a biomarker of cardiac injury associated with a worse prognosis in COVID-19. We explored how hs-cTnT could potentially be…

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Characterisation of Ferritin–Lymphocyte Ratio in COVID-19

Alexander Liu; Robert Hammond; Kenneth Chan dkk.

Biomedicines, Vol. 11 No. 10 · 2023 · Inggris · DOAJ Scopus

Introduction: The ferritin–lymphocyte ratio (FLR) is a novel inflammatory biomarker for the assessment of acute COVID-19 patients. However, the prognostic value of FLR for predicting adverse clinical outcomes in COVID-19 remains unclear, which hinders its clinical translation. Methods: We…

Low CRB-65 Scores Effectively Rule out Adverse Clinical Outcomes in COVID-19 Irrespective of Chest Radiographic Abnormalities

Alexander Liu; Robert Hammond; Kenneth Chan dkk.

Biomedicines, Vol. 11 No. 9 · 2023 · Inggris · DOAJ Scopus

Background: CRB-65 (Confusion; Respiratory rate ≥ 30/min; Blood pressure ≤ 90/60 mmHg; age ≥ 65 years) is a risk score for prognosticating patients with COVID-19 pneumonia. However, a significant proportion of COVID-19 patients have normal chest X-rays (CXRs). The influence of CXR abnormalities on…

Incremental value of left atrial booster and reservoir strain in predicting atrial fibrillation in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance study

Betty Raman; Robert W. Smillie; Masliza Mahmod dkk.

Journal of Cardiovascular Magnetic Resonance, Vol. 23 No. 1 · 2021 · Inggris · DOAJ Scopus

Abstract Background Left atrial (LA) size and function are known predictors of new onset atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) patients. Components of LA deformation including reservoir, conduit, and booster function provide additional information on atrial mechanics…

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction

Wei Yang; Fu Liang Ng; Kenneth Chan dkk.

PLOS Genetics, Vol. 12 No. 7 · 2016 · Inggris · PLOS Scopus

Genome-wide association studies have revealed an association between coronary heart disease (CHD) and genetic variation on chromosome 13q34, with the lead single nucleotide polymorphism rs4773144 residing in the COL4A2 gene in this genomic region. We investigated the functional effects of this…