15 results for "LIN Lin"
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Cuproptosis: lipoylated TCA cycle proteins-mediated novel cell death pathway
In a recent study published in Science , Tsvetkov et al 1 . shed a light on a new form of cell death, copper-dependent cell death (termed cuproptosis). They defined “cuproptosis” as a nonapoptotic cell death pathway. They have demonstrated that copper directly binds to lipoylated components of the…
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Single‐cell RNA sequencing technologies and applications: A brief overview
Single-cell RNA sequencing (scRNA-seq) technology has become the state-of-the-art approach for unravelling the heterogeneity and complexity of RNA transcripts within individual cells, as well as revealing the composition of different cell types and functions within highly organized…
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86 PFLOPS Deep Potential Molecular Dynamics simulation of 100 million atoms with ab initio accuracy
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Large Second-Harmonic Response and Giant Birefringence of CeF 2 (SO 4 ) Induced by Highly Polarizable Polyhedra
Second-harmonic generation (SHG) response and birefringence are two critically important properties of nonlinear optical (NLO) materials. However, the simultaneous optimization of these two key properties remains a major challenge because of their contrasting microstructure requirements. Herein, we…
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Advances in lithium niobate photonics: development status and perspectives
Lithium niobate (LN) has experienced significant developments during past decades due to its versatile properties, especially its large electro-optic (EO) coefficient. For example, bulk LN-based modulators with high speeds and a superior linearity are widely used in typical fiber-optic…
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Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2
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Multiplexed Nanomaterial-Based Sensor Array for Detection of COVID-19 in Exhaled Breath
This article reports on a noninvasive approach in detecting and following-up individuals who are at-risk or have an existing COVID-19 infection, with a potential ability to serve as an epidemic control tool. The proposed method uses a developed breath device composed of a nanomaterial-based hybrid…
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Evaluating the evidence for exponential quantum advantage in ground-state quantum chemistry
Due to intense interest in the potential applications of quantum computing, it is critical to understand the basis for potential exponential quantum advantage in quantum chemistry. Here we gather the evidence for this case in the most common task in quantum chemistry, namely, ground-state energy…
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S iesta : Recent developments and applications
A review of the present status, recent enhancements, and applicability of the Siesta program is presented. Since its debut in the mid-1990s, Siesta's flexibility, efficiency, and free distribution have given advanced materials simulation capabilities to many groups worldwide. The core…
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SIESTA: recent developments and applications
A review of the present status, recent enhancements, and applicability of the SIESTA program is presented. Since its debut in the mid-nineties, SIESTA's flexibility, efficiency and free distribution has given advanced materials simulation capabilities to many groups worldwide. The core…
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GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
Cancer metabolism is rewired to support cell survival in response to intrinsic and environmental stressors. Identification of strategies to target these adaptions is an area of active research. We previously described a cytosolic aspartate aminotransaminase (GOT1)-driven pathway in pancreatic…
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Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis