8 hasil untuk "Li-Si Zeng"

LncRNA FAM66C enhances gastric cancer proliferation and chemoresistance through phosphorylating nuclear YAP protein

Chao Yang; Hai-Lan Guan; Li-Hua Ji dkk.

Frontiers in Pharmacology, Vol. 17 · 2026 · Inggris · DOAJ Scopus

BackgroundChemoresistance is one of the causes of death in patients with gastric cancer (GC). Extensive studies have demonstrated that lncRNAs have important implications in GC chemoresistance, but their underlying mechanisms in driving GC chemoresistance remain poorly understood. Here, we…

Elevated circulating tumor cells and squamous cell carcinoma antigen levels predict poor survival for patients with locally advanced cervical cancer treated with radiotherapy

Yue-Feng Wen; Tian-Tian Cheng; Xiao-Long Chen dkk.

PLOS ONE, Vol. 13 No. 10 · 2018 · Inggris · PLOS Scopus

Objective: To evaluate the prognostic effects of combining serum circulating tumor cells (CTCs) and squamous cell carcinoma antigen (SCC-Ag) levels on patients with locally advanced cervical cancer treated with radiotherapy. Methods: Ninety-nine patients with locally advanced cervical cancer…

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Prognostic impact of pretherapeutic gamma-glutamyltransferase on patients with nasopharyngeal carcinoma

Yue-Feng Wen; Xian-Zi Yang; Li-Si Zeng dkk.

PLOS ONE, Vol. 12 No. 2 · 2017 · Inggris · PLOS Scopus

Background: Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the metabolism of glutathione. Studies suggested that GGT played an important role in the tumor development, progression, invasion and drug resistance and prognosis. The association between GGT and prognosis of…

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Predictive Value of LINC01133 for Unfavorable Prognosis was Impacted by Alcohol in Esophageal Squamous Cell Carcinoma

Xian-Zi Yang; Qing-Jun He; Tian-Tian Cheng dkk.

Cellular Physiology and Biochemistry, Vol. 48 No. 1 · 2018 · Inggris · DOAJ Scopus

Background/Aims: Considerable evidence indicates that long noncoding RNAs (lncRNAs) exert importantly regulatory functions during human cancer initiation and progression and are promising biotargets in the flight against cancer. Methods: In this study, we evaluated the role of the lncRNA LINC01133…

LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway

Xian-Zi Yang; Tian-Tian Cheng; Qing-Jun He dkk.

Molecular Cancer, Vol. 17 No. 1 · 2018 · Inggris · DOAJ Scopus

Abstract Background Gastric cancer (GC) is a common malignancy and frequent cause of cancer-related death. Long non-coding RNAs (lncRNAs) have emerged as important regulators and tissue-specific biomarkers of multiple cancers, including GC. Recent evidence has indicated that the novel lncRNA…

The Latest Battles Between EGFR Monoclonal Antibodies and Resistant Tumor Cells

Wen-Qi Cai; Li-Si Zeng; Li-Feng Wang dkk.

Frontiers in Oncology, Vol. 10 · 2020 · Inggris · DOAJ Scopus

Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor involved in homeostatic regulation of normal cells and carcinogenesis of epithelial malignancies. With rapid development of the precision medicine era, a series of new therapies targeting EGFR are underway. Four EGFR monoclonal…