17 hasil untuk "Mehreen Lateef"

Novel Crown Ether-Functionalized Fusidic Acid Butyl Ester: Synthesis, Biological Evaluation, In Silico ADMET, and Molecular Docking Studies

Hira Sultan; Nuzhat Arshad; Mehreen Lateef

Molecules, Vol. 30 No. 9 · 2025 · Inggris · DOAJ Scopus

Crown ethers have gained importance in the field of medicine because of their resemblance to natural ionophores like valinomycin. With the goal of developing new pharmacologically important crown ethers, a novel series of crown ethers linked with Fusidic acid butyl ester 10a–d were synthesized and…

Relationship of Age, BMI, Serum Calcium and Estradiol with BMD in Postmenopausal Osteoporotic Females

Mukhtiar Baig; Mehreen Lateef; Abid Azhar

Journal of Bahria University Medical and Dental College, Vol. 1 No. 1 · 2011 · Inggris · DOAJ

Introduction: The current study was designed to investigate the relationship of age, body mass index (BMI), serum calcium and estradiol with bone mineral density (BMD) in postmenopausal females with and without osteoporosis. Subjects & Methods: One hundred females were included in this study and…

Food Security Challenges Emanating from COVID-19

Shizma Junejo; Quratulain Javaid; Mehreen Lateef

Life and Science, Vol. 5 No. 4 · 2024 · Inggris · DOAJ

…following the COVID-19 pandemic. How to cite this: Junejo S, Javaid Q, Lateef M. Food Security Challenges Emanating from COVID-19. Life and Science. 2024; 5(4): 573-. doi: http://doi.org/10.37185/LnS.1.1.574

Serum Leptin and Bone Turnover Markers in Postmenopausal Osteoporosis

Mehreen Lateef; Mukhtiar Baig; Abid Azhar

Topics in Osteoporosis · 2013 · Inggris · IntechOpen

Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material

Mehreen Lateef; Sadia Farheen; Beena Naqvi dkk.

Pakistan Journal of Pharmaceutical Sciences, Vol. 33 No. 3 · 2020 · Inggris · DOAJ Scopus

Extracts of nine plants were studied for DPPH radical scavenging and reducing abilities. Pentatropis spiralis, Calotropis procera, Helitropium curassavicum, Withania somnifera and Chenopodium album showed reducing power ranging from 34% to 146%. Suaeda fruticosa, Trianthema portulacastrum, Pluchea…

Impact of Vitamin C as an Adjuvant Agent on Glycemic Indices in Type 2 Diabetes Mellitus: Randomized Clinical Trial

Shabzain Ishrat; Talea Hoor; Muhammad Sajid Abbas Jaffri dkk.

Journal of Bahria University Medical and Dental College, Vol. 11 No. 3 · 2021 · Inggris · DOAJ

Objectives: To evaluate the effects of adjuvant vitamin C therapy with oral hypoglycemic on FBS, RBS and HbA1c and to find out the correlation of Vitamin C with glycemic indices. Study Design & Settings: This randomized open label clinical trial was conducted at Bahria University Medical & Dental…

Decreased muscle strength in adjuvant-induced rheumatoid arthritis animal model: A relationship to behavioural assessments

Maham Ghouri; Mehreen Lateef; Laraib Liaquat dkk.

Heliyon, Vol. 10 No. 1 · 2024 · Inggris · DOAJ Scopus

Rheumatoid arthritis (RA) is an autoimmune disorder with unknown aetiology. Patients suffering from RA face persistent pain due to joint inflammation, and tissue destruction. Behavioural phenotyping is an approach to target the role of different behavioural traits associated with disease…

New bioactive triaryl triglyceride esters: Synthesis, characterization and biological activities

Tanzila Arshad; Hamdullah Khadim Sheikh; Mehdi Hassan Kazmi dkk.

Bangladesh Journal of Pharmacology, Vol. 13 No. 4 · 2018 · Inggris · DOAJ Scopus

Four new bioactive aryl triester derivatives of glycerol and benzoic acids were synthesized. The synthetic compounds were studied for their antimicrobial and urease inhibition activities. Esterification was carried out by using carbonyldiimidazole to enhance the acyl elimination addition reaction…

1,3,5-Thiadiazinane thione derivatives as significant urease inhibitors

Nuzhat Arshad; Mehreen Lateef; Jamshed Hashim dkk.

Pakistan Journal of Pharmaceutical Sciences, Vol. 35 No. 3 · 2022 · Inggris · DOAJ Scopus

We report the promising urease inhibitory activity of four sets of tetrahydro thiadiazine thiones (THTT) namely 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine thiones: THTT 5˗8 (set A) having alkyl/aryl substituents at N-3 and N-5 positions; THTT 9˗12 (set B) and THTT 13˗14 (set C) with…

Effect of Exercise on Salivary pH, Amylase, Mucin, and Total Protein Concentration of Unstimulated Whole Saliva in Pakistani Cohort

Saqib Ali; Beenish Fatima Alam; Malik Arshman Khan dkk.

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, Vol. 26 · 2025 · Portugis · DOAJ Scopus

Objective: To assess the effects of physical exercise on salivary pH, amylase, mucin, and total protein concentration. Material and Methods: Saliva samples were collected from 34 participants (21 males, 13 females) at four time points: rest (control), moderate-intensity exercise, high-intensity…

A novel approach to urease inhibition and antioxidant therapeutics by using AgNPs-doped TiO2NPs stabilized by short chain pyrazole carbothioamide derivatives

Rafia Usman Khan; Faiza Saleem; Mehreen Lateef dkk.

Pakistan Journal of Pharmaceutical Sciences, Vol. 38 No. 4 · 2025 · Inggris · DOAJ Scopus

This study details our approach to the synthesis, characterization and applications of silver nanoparticles (AgNPs) doped titanium dioxide nanoparticles (TiO2NPs). Prior to doping both the nanoparticles AgNPs and TiO2NPs were stabilized by a new small chain 5-(3-Nitrophenyl)…

Sessilifol A and B, Urease Inhibitory Pimarane-type Diterpenes from

Sadia Khan; Muhammad Shaiq Ali; Zeeshan Ahmed dkk.

Natural Product Communications, Vol. 12 · 2017 · Inggris · DOAJ Scopus

New pimarane type diterpenes named sessilifol A (1) and B (2) have been isolated from the EtOH soluble fraction of Hymenocrater sessilifolius Benth., along with eight known constituents cirsimaritin (3), gardenin C (4), β -sitosterol (5), saringosterol (6), β -sitosterol glucoside (7), ursolic acid…

Combined experimental and computational approach toward biological, physicochemical and quantum chemical aspects of substituted 1-[5-phenyl-3-(2-trifluoromethyl-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone

Faiz Rasool; Ajaz Hussain; Tania Shamim Rizvi dkk.

Results in Chemistry, Vol. 5 · 2023 · Inggris · DOAJ Scopus

In current work, three N-acetyl pyrazoline derivatives (1–3) have been prepared via 1,4-addition reaction of hydrazine on chalcones, followed by cyclization of the adduct in the presence of acetic acid. The structural interpretation of synthesized compounds was accomplished using various…

N‑Aryl-3,4-dihydroisoquinoline Carbothioamide Analogues as Potential Urease Inhibitors

Fayaz Ali; Shahbaz Shamim; Mehreen Lateef dkk.

ACS Omega, Vol. 6 No. 24 · 2021 · Inggris · DOAJ Scopus

New anthrarobin acyl derivatives as butyrylcholinesterase inhibitors: synthesis, in vitro and in silico studies

Mehreen Lateef; Abid Azhar; Bina S. Siddiqui dkk.

Heliyon, Vol. 3 No. 7 · 2017 · Inggris · DOAJ Scopus

To treat Alzheimer's disease (AD), the available candidates are effective only against mild AD or have side effects. So, a study was planned to synthesis new candidates that may have good potential to treat AD. A series of new anthrarobin acyl derivatives (2–8) were synthesized by the reaction of…

A New Ceramide and Biflavonoid from the Leaves of (Chrysobalanaceae)

Martial F. E. Adjapmoh; Flavien A. A. Toze; Jules L. Songue dkk.

Natural Product Communications, Vol. 11 · 2016 · Inggris · DOAJ Scopus

A new ceramide and a new biflavonoid named parinaramide ( 1 ) and sparinaritin ( 2 ), respectively, have been isolated along with ten known compounds, kaempferol, quercetin, taxifolin, taxifolin-3- O -rhamnoside, lupeol, betulinic acid, ursolic acid, 2α-hydroxy-ursolic acid…

Synthesis, Urease Inhibition and Molecular Modelling Studies of Novel Derivatives of the Naturally Occurring β-Amyrenone

Jean J. K. Bankeu; Hira Sattar; Yannick S. F. Fongang dkk.

Natural Products and Bioprospecting, Vol. 9 No. 1 · 2018 · Inggris · DOAJ Scopus

Abstract Urease enzyme (UE) has been reported to be a potent virulence factor for Helicobacter pylori (HP) bacteria indicated to be responsible for various gastrointestinal diseases. Therefore, the spread of HP, currently regarded by the World Health Organization as a class 1 carcinogen, could be…