18 hasil untuk "Min-Han Lin"

Synthesis and Optical Characterization of Oxygen-Incorporated ZnS(1–x)Ox for UV–Visible Color Palette Light-Emission Matter

Min-Han Lin; Ching-Hwa Ho

ACS Omega, Vol. 2 No. 8 · 2017 · Inggris · DOAJ Scopus

Discrimination of Red Wines with a Gas-Sensor Array Based on a Surface-Acoustic-Wave Technique

Min-Han Lin; Ling-Yi Ke; Da-Jeng Yao

Micromachines, Vol. 10 No. 11 · 2019 · Inggris · DOAJ Scopus

We applied a thermal-desorption gas-chromatograph mass-spectrometer (TD-GC−MS) system to identify the marker volatile organic compounds (VOCs) in the aroma of red wine. After obtaining the marker VOC, we utilized surface acoustic waves (SAWs) to develop a highly sensitive sensing system as…

The Study of Near-Band-Edge Property in Oxygen-Incorporated ZnS for Acting as an Efficient Crystal Photocatalyst

Min-Han Lin; Perumalswamy Sekar Parasuraman; Ching-Hwa Ho

ACS Omega, Vol. 3 No. 6 · 2018 · Inggris · DOAJ Scopus

Evaluation of Nanodiamond-in-Oil Emulsion with Snake Venom to Enhance Potent Antibody Induction in Mice and Rabbits

Min-Han Lin; Long-Jyun Su; Hsin-Hung Lin dkk.

Nanomaterials, Vol. 15 No. 19 · 2025 · Inggris · DOAJ Scopus

Nanodiamonds (NDs) are an innovative material in biomedical applications based on their excellent biocompatibility, nanoscale dimensions, and high surface area. In this study, we evaluated the potential of ND-in-oil emulsion to induce potent antibody responses in animals immunized with cobra venom…

The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing

Wei Shen Aik; Min-Han Lin; Dazhi Tan dkk.

PLOS ONE, Vol. 12 No. 10 · 2017 · Inggris · PLOS Scopus

Unlike canonical pre-mRNAs, animal replication-dependent histone pre-mRNAs lack introns and are processed at the 3’-end by a mechanism distinct from cleavage and polyadenylation. They have a 3’ stem loop and histone downstream element (HDE) that are recognized by stem-loop binding protein (SLBP)…

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A distinct holoenzyme organization for two-subunit pyruvate carboxylase

Philip H. Choi; Jeanyoung Jo; Yu-Cheng Lin dkk.

Nature Communications, Vol. 7 No. 1 · 2016 · Inggris · DOAJ Scopus

Pyruvate carboxylases are homotetrameric enzymes in eukaryotes and most bacteria. Here, the authors report the structure of an unusual two-subunit form of the enzyme from the Gram-negative bacterium Methylobacillus flagellates, revealing an unexpected α2β4stoichiometry.

Inositol hexakisphosphate is required for Integrator function

Min-Han Lin; Madeline K. Jensen; Nathan D. Elrod dkk.

Nature Communications, Vol. 13 No. 1 · 2022 · Inggris · DOAJ Scopus

Integrator is a multi-subunit protein complex with roles in noncoding RNA 3′-end processing and mRNA transcription attenuation. Here, the authors reveal a conserved binding site for IP6 in the Integrator cleavage module and show that IP6 binding is required for Integrator function.

Development of a Broad-Spectrum Antiserum against Cobra Venoms Using Recombinant Three-Finger Toxins

Bing-Sin Liu; Bo-Rong Jiang; Kai-Chieh Hu dkk.

Toxins, Vol. 13 No. 8 · 2021 · Inggris · DOAJ Scopus

Three-finger toxins (3FTXs) are the most clinically relevant components in cobra (genus Naja) venoms. Administration of the antivenom is the recommended treatment for the snakebite envenomings, while the efficacy to cross-neutralize the different cobra species is typically limited, which is…

Monitoring the Disulfide Bonds of Folding Isomers of Synthetic CTX A3 Polypeptide Using MS-Based Technology

Sheng-Yu Huang; Tin-Yu Wei; Bing-Shin Liu dkk.

Toxins, Vol. 11 No. 1 · 2019 · Inggris · DOAJ Scopus

Native disulfide formation is crucial to the process of disulfide-rich protein folding in vitro. As such, analysis of the disulfide bonds can be used to track the process of the folding reaction; however, the diverse structural isomers interfere with characterization due to the non-native disulfide…

Protective Efficacy of VP1-Specific Neutralizing Antibody Associated with a Reduction of Viral Load and Pro-Inflammatory Cytokines in Human SCARB2-Transgenic Mice

Hsuen-Wen Chang; Yi-Wen Lin; Hui-Min Ho dkk.

PLoS ONE, Vol. 8 No. 7 · 2013 · Inggris · PLOS Scopus

Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the Asian-Pacific region. Recently we have successfully developed transgenic mice expressing human scavenger receptor class B member 2 (hSCARB2…

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Immunization with deglycosylated H7N9 VLP enhances cross-strain protective antibody responses against avian influenza H7N9 variants in mice

Asmaul Husna; Yu-Chieh Cheng; Chia-Chun Lai dkk.

Vaccine: X, Vol. 31 · 2026 · Inggris · DOAJ Scopus

Introduction: The rapidly evolving avian influenza H7N9 virus remains a threaten to public health globally. There is an urgent need to develop broad-spectrum vaccines capable of eliciting functional cross-strain protective immunity against emerging viral variants. Methods: N-linked glycosylation…

Immunological evaluation of a novel HLA-A2 restricted phosphopeptide of tumor associated Antigen, TRAP1, on cancer therapy

Min-Han Lin; Kuan-Yin Shen; Bing-Sin Liu dkk.

Vaccine: X, Vol. 1 · 2019 · Inggris · DOAJ Scopus

The tumor necrosis factor receptor associated protein 1 (TRAP1) is a mitochondria chaperon protein that has been previously implicated as a target for cancer therapy due to its expression level is linked to tumor progression. In this study, an immunodominant phosphopeptide of TRAP1 was identified…

Identification of Immunoreactive Peptides of Toxins to Simultaneously Assess the Neutralization Potency of Antivenoms against Neurotoxicity and Cytotoxicity of Naja atra Venom

Bing-Sin Liu; Wen-Guey Wu; Min-Han Lin dkk.

Toxins, Vol. 10 No. 1 · 2017 · Inggris · DOAJ Scopus

Assessing the neutralization capability of nonlethal but medically relevant toxins in venom has been a challenging task. Nowadays, neutralization efficacy is evaluated based simply on the survival rates of animals injected with antivenom together with a predefined dose of venom, which can determine…

The L-lactate dehydrogenases of Pseudomonas aeruginosa are conditionally regulated but both contribute to survival during macrophage infection

Lindsey C. Florek; Xi Lin; Yu-Cheng Lin dkk.

mBio, Vol. 15 No. 9 · 2024 · Inggris · DOAJ Scopus

ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that thrives in environments associated with human activity, including soil and water altered by agriculture or pollution. Because L-lactate is a significant product of plant and animal metabolism, it can serve as a carbon source for P…

MDCK-Adaptive Mutation of A169S Changes Glycosylation Pattern of Hemagglutinin and Enhances MDCK-Based H7N9 Vaccine Virus Production without Loss of Antigenicity and Immunogenicity

Po-Ling Chen; Tsai-Chuan Weng; Chia-Chun Lai dkk.

Vaccines, Vol. 12 No. 3 · 2024 · Inggris · DOAJ Scopus

The adaptation of egg-derived H7N9 candidate vaccine virus (CVV) in the mammalian cell line is an approach to developing a high-growth virus strain for the mass production of vaccine manufacturing. The adaptive mutations that occur in hemagglutinin (HA) are critical to the activity and potency of…

Fabrication of multianalyte CeO2 nanograin electrolyte–insulator–semiconductor biosensors by using CF4 plasma treatment

Chyuan Haur Kao; Hsiang Chen; Fang Yao Stephen Hou dkk.

Sensing and Bio-Sensing Research, Vol. 5 · 2015 · Inggris · DOAJ Scopus

Multianalyte CeO2 biosensors have been demonstrated to detect pH, glucose, and urine concentrations. To enhance the multianalyte sensing capability of these biosensors, CF4 plasma treatment was applied to create nanograin structures on the CeO2 membrane surface and thereby increase the contact…