12 hasil untuk "Muhammad Hasnat"
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Artikel Jurnal
Stress levels among pre-clinical Medical students and their coping strategies
BACKGROUND & OBJECTIVE: Stress is no doubt prevalent among medical students. Insight into how different personality types cope with this challenge might give the opportunity to healthcare authorities to devise a more standardized guideline for conducting a psychological aptitude test at the time of…
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Artikel Jurnal
Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production
Abstract Osteopontin (OPN) is a multifunctional cytokine that can impact cancer progression. Therefore, it is crucial to determine the key factors involved in the biological role of OPN for the development of treatment. Here, we investigated that OPN promoted hepatocellular carcinoma (HCC) cell…
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Artikel Jurnal
Prevalence of Biliary Dilatation in Patients with Pancreatitis on MDCT and Its Correlation with CT Severity Index
ABSTRACT OBJECTIVES This study aimed to determine the prevalence of biliary dilatation in patients with pancreatitis on multidetector computed tomography (MDCT) and to evaluate its association with the CT Severity Index (CTSI). METHODOLOGY Analytical cross-sectional study. Department of Radiology…
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Artikel Jurnal
A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein
Previously, we proposed a new perspective of triptolide (TP)-associated hepatotoxicity: liver hypersensitivity upon lipopolysaccharide (LPS) stimulation. However, the mechanisms for TP/LPS-induced hepatotoxicity remained elusive. The present study aimed to clarify the role of LPS in TP/LPS-induced…
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Artikel Jurnal
Diagnostic Accuracy of Barium Swallow Study for Differentiating Benign and Malignant Esophageal Strictures Using Endoscopy with Biopsy as Gold Standard
ABSTRACT OBJECTIVES This study aimed to determine the diagnostic accuracy of barium swallow for differentiating malignant from benign oesophageal strictures using endoscopy with biopsy as the reference standard. METHODOLOGY This cross-sectional validation study included 88 consecutively selected…
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Artikel Jurnal
Application Perspectives of Nanomedicine in Cancer Treatment
Cancer is a disease that seriously threatens human health. Based on the improvement of traditional treatment methods and the development of new treatment modes, the pattern of cancer treatment is constantly being optimized. Nanomedicine plays an important role in these evolving tumor treatment…
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Artikel Jurnal
Macrophage malfunction in Triptolide-induced indirect hepatotoxicity
Background and Objective: Indirect hepatotoxicity is a new type of drug-induced hepatotoxicity in which the character of a drug that may induce its occurrence and the underlying mechanism remains elusive. Previously, we proved that Triptolide (TP) induced indirect hepatotoxicity upon LPS…
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Artikel Jurnal
Identification of putative inhibitors of human pancreatic α-amylase from phytochemicals using molecular docking and computational analysis
Background: Diabetes mellitus is a global chronic metabolic disorder characterized by elevated blood glucose levels, primarily due to impaired insulin activity or secretion. α-amylase, a key enzyme in carbohydrate digestion, is a validated molecular target for controlling postprandial hyperglycemia…
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Artikel Jurnal
Total C-21 Steroidal Glycosides From Baishouwu Ameliorate Hepatic and Renal Fibrosis by Regulating IL-1β/MyD88 Inflammation Signaling
Fibrosis is a worldwide public health problem, which typically results from chronic diseases and often leads to organ malfunction. Chronic inflammation has been suggested to be the major trigger for fibrogenesis, yet mechanisms by which inflammatory signals drive fibrogenesis have not been fully…