19 results for "Nicholas Generous"

Global disease monitoring and forecasting with Wikipedia.

Nicholas Generous; Geoffrey Fairchild; Alina Deshpande et al.

PLoS Computational Biology, Vol. 10 No. 11 · 2014 · English · DOAJ Scopus

Infectious disease is a leading threat to public health, economic stability, and other key social structures. Efforts to mitigate these impacts depend on accurate and timely monitoring to measure the risk and progress of disease. Traditional, biologically-focused monitoring techniques are accurate…

Also available at: PLOS

Google Health Trends performance reflecting dengue incidence for the Brazilian states

Daniel Romero-Alvarez; Nidhi Parikh; Dave Osthus et al.

BMC Infectious Diseases, Vol. 20 No. 1 · 2020 · English · DOAJ Scopus

Abstract Background Dengue fever is a mosquito-borne infection transmitted by Aedes aegypti and mainly found in tropical and subtropical regions worldwide. Since its re-introduction in 1986, Brazil has become a hotspot for dengue and has experienced yearly epidemics. As a notifiable infectious…

Epidemiological Data Challenges: Planning for a More Robust Future Through Data Standards

Geoffrey Fairchild; Byron Tasseff; Hari Khalsa et al.

Frontiers in Public Health, Vol. 6 · 2018 · English · DOAJ Scopus

Accessible epidemiological data are of great value for emergency preparedness and response, understanding disease progression through a population, and building statistical and mechanistic disease models that enable forecasting. The status quo, however, renders acquiring and using such data…

Forecasting the 2013-2014 influenza season using Wikipedia.

Kyle S Hickmann; Geoffrey Fairchild; Reid Priedhorsky et al.

PLoS Computational Biology, Vol. 11 No. 5 · 2015 · English · DOAJ Scopus

Infectious diseases are one of the leading causes of morbidity and mortality around the world; thus, forecasting their impact is crucial for planning an effective response strategy. According to the Centers for Disease Control and Prevention (CDC), seasonal influenza affects 5% to 20% of the U.S…

Also available at: PLOS

Advancing a framework to enable characterization and evaluation of data streams useful for biosurveillance.

Kristen J Margevicius; Nicholas Generous; Kirsten J Taylor-McCabe et al.

PLoS ONE, Vol. 9 No. 1 · 2014 · English · DOAJ Scopus

In recent years, biosurveillance has become the buzzword under which a diverse set of ideas and activities regarding detecting and mitigating biological threats are incorporated depending on context and perspective. Increasingly, biosurveillance practice has become global and interdisciplinary…

Also available at: PLOS

Selecting essential information for biosurveillance--a multi-criteria decision analysis.

Nicholas Generous; Kristen J Margevicius; Kirsten J Taylor-McCabe et al.

PLoS ONE, Vol. 9 No. 1 · 2014 · English · DOAJ Scopus

The National Strategy for Biosurveillance defines biosurveillance as "the process of gathering, integrating, interpreting, and communicating essential information related to all-hazards threats or disease activity affecting human, animal, or plant health to achieve early detection and warning…

Also available at: PLOS

An extensible framework and database of infectious disease for biosurveillance

Ashlynn R. Daughton; Reid Priedhorsky; Geoffrey Fairchild et al.

BMC Infectious Diseases, Vol. 17 No. 1 · 2017 · English · DOAJ Scopus

Abstract Biosurveillance, a relatively young field, has recently increased in importance because of increasing emphasis on global health. Databases and tools describing particular subsets of disease are becoming increasingly common in the field. Here, we present an infectious disease database that…

Higher education responses to COVID-19 in the United States: Evidence for the impacts of university policy

Brennan Klein; Nicholas Generous; Matteo Chinazzi et al.

PLOS Digital Health, Vol. 1 No. 6 · 2022 · English · DOAJ Scopus

With a dataset of testing and case counts from over 1,400 institutions of higher education (IHEs) in the United States, we analyze the number of infections and deaths from SARS-CoV-2 in the counties surrounding these IHEs during the Fall 2020 semester (August to December, 2020). We find that…

Also available at: DOAJ, PLOS

Defending Our Public Biological Databases as a Global Critical Infrastructure

Jacob Caswell; Jason D. Gans; Nicholas Generous et al.

Frontiers in Bioengineering and Biotechnology, Vol. 7 · 2019 · English · DOAJ Scopus

Progress in modern biology is being driven, in part, by the large amounts of freely available data in public resources such as the International Nucleotide Sequence Database Collaboration (INSDC), the world's primary database of biological sequence (and related) information. INSDC and similar…

Using heterogeneous data to identify signatures of dengue outbreaks at fine spatio-temporal scales across Brazil.

Lauren A Castro; Nicholas Generous; Wei Luo et al.

PLoS Neglected Tropical Diseases, Vol. 15 No. 5 · 2021 · English · DOAJ Scopus

Dengue virus remains a significant public health challenge in Brazil, and seasonal preparation efforts are hindered by variable intra- and interseasonal dynamics. Here, we present a framework for characterizing weekly dengue activity at the Brazilian mesoregion level from 2010-2016 as time series…

Also available at: PLOS

The Biosurveillance Analytics Resource Directory (BARD): Facilitating the Use of Epidemiological Models for Infectious Disease Surveillance

Kristen J Margevicius; Nicholas Generous; Esteban Abeyta et al.

PLOS ONE, Vol. 11 No. 1 · 2016 · English · PLOS Scopus

Epidemiological modeling for infectious disease is important for disease management and its routine implementation needs to be facilitated through better description of models in an operational context. A standardized model characterization process that allows selection or making manual comparisons…

Also available at: DOAJ