7 hasil untuk "Saba Imdad"

Effect of Aerobic Exercise on Oxidative Stress and Inflammatory Response During Particulate Matter Exposure in Mouse Lungs

Byunghun So; Jinhan Park; Junho Jang dkk.

Frontiers in Physiology, Vol. 12 · 2022 · Inggris · DOAJ Scopus

Regular exercise provides several health benefits that can improve the cardiovascular and musculoskeletal systems, but clear evidence on the effect of exercise-induced hyperventilation in particulate matter (PM) exposure is still lacking. This study aimed to investigate the effects of exercise in…

Proteomic analysis of the effect of high-fat-diet and voluntary physical activity on mouse liver

Byunghun So; Li Li Ji; Saba Imdad dkk.

PLOS ONE, Vol. 17 No. 8 · 2022 · Inggris · PLOS Scopus

Nonalcoholic fatty liver disease (NALFD), characterized by an abnormal accumulation of triglycerides in hepatocytes, is closely linked to insulin resistance, metabolic syndrome, and changes in lipogenesis in the liver. The accumulation of hepatic lipids can lead to a range of pathologies from mild…

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Identification and Validation of an Antivirulence Agent Targeting HlyU-Regulated Virulence in Vibrio vulnificus

Saba Imdad; Akhilesh Kumar Chaurasia; Kyeong Kyu Kim

Frontiers in Cellular and Infection Microbiology, Vol. 8 · 2018 · Inggris · DOAJ Scopus

Antimicrobial resistance (AMR) in pathogens is the result of indiscriminate use of antibiotics and consequent metabolic/genetic modulation to evolve survival strategies and clonal-selection in AMR strains. As an alternative to antibiotic treatment, antivirulence strategies are being developed, not…

Identification of 2′,4′-Dihydroxychalcone as an Antivirulence Agent Targeting HlyU, a Master Virulence Regulator in Vibrio vulnificus

Saba Imdad; Nayab Batool; Subhra Pradhan dkk.

Molecules, Vol. 23 No. 6 · 2018 · Inggris · DOAJ Scopus

The emergence of antimicrobial resistance and rapid acclimation allows Vibrio vulnificus to rapidly propagate in the host. This problematic pathological scenario can be circumvented by employing an antivirulence strategy, treating Vibrio infections without hindering the bacterial growth. We…

Temporal variations in the gut microbial diversity in response to high-fat diet and exercise

Saba Imdad; Byunghun So; Junho Jang dkk.

Scientific Reports, Vol. 14 No. 1 · 2024 · Inggris · DOAJ Scopus

Abstract High-fat diet-induced obesity is a pandemic caused by an inactive lifestyle and increased consumption of Western diets and is a major risk factor for diabetes and cardiovascular diseases. In contrast, exercise can positively influence gut microbial diversity and is linked to a decreased…

Effect of aerobic exercise and particulate matter exposure duration on the diversity of gut microbiota

Saba Imdad; Jin-Hee Kim; Byunghun So dkk.

Animal Cells and Systems, Vol. 28 No. 1 · 2024 · Inggris · DOAJ Scopus

Inhalation of ambient particulate matter (PM) can disrupt the gut microbiome, while exercise independently influences the gut microbiome by promoting beneficial bacteria. In this study, we analyzed changes in gut microbial diversity and composition in response to combined interventions of PM…